Translation of Addictions Science Into Practice

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Overview

Recent advances in the understanding of the genetic, neurochemical, behavioral and cultural underpinnings of addiction have led to rapid advances in the understanding of addiction as a disease. In fact, advances in basic science and the development of new pharmacological and behavioral therapies associated with them are appearing faster than can be assimilated not only by clinical researchers but practitioners and policy makers as well. Translation of science-based addictions knowledge into improved prevention, assessment and treatment, and communication of these changes to researchers and practitioners are significant challenges to the field.

The general aim of this book is to summarize current and potential linkages between advances in addiction science and innovations in clinical practice. Whilst this book is primarily focused on translation, it also encompasses some scientific advances that are relevant to dissemination, and the book is itself a tool for disseminating innovative thinking.

The goal is to generate interest in application opportunities from both recent research and theoretical advances.

• Provides a much needed resource for translating current research into clinical practice
• Focuses upon alcohol, tobacco, and substance abuse addictions
• Addresses method of research and best dissemination techniques

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is an interesting new book that evolved from an international conference in 2004, Crossing Boundaries: Implications of Advances in Basic Sciences for the Management of Addiction. Written and edited by a group of internationally recognized addiction researchers, this book serves as a guide to bringing basic science knowledge to patient care.
Purpose: The purpose of the book, according to the editors "is to provide a needed link between advances in addiction science and innovations in clinical practice." The editors note that presently, even though there are now a number of adjunctive pharmacotherapies for addiction, many practitioners tend not use them and feel they are ineffective, in spite of evidence of efficacy. The editors hope to educate clinicians and show the utility of bringing basic science advances to the bedside.
Audience: The intended audience includes clinicians who treat patients with substance-related disorders.
Features: The first of the book's five sections deals with the basic neurobiology and genetics related to addictions. Pharmacotherapy is the focus of the second section with interesting chapters on plasticity, agonist treatments, and neuromodulation. Addiction is also related to social cognition, context, and motivational systems, and section three details the research findings on craving, impulse control, and affect. Addiction and social justice are related issues and section four summarizes public policies, ethical issues and practices related to intervention. The final section and chapter provides an overview of the processes involved in translating basic science to clinical practice as well as alternative pathways for improved diagnosis and treatment of these all too common disorders. Each chapter ends with relevant and timely references of the scientific literature.
Assessment: This is an excellent book that will help clinicians synthesize basic science information for application to improved clinical care of patients. I highly recommend it.
From The Critics
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is an interesting new book that evolved from an international conference in 2004, Crossing Boundaries: Implications of Advances in Basic Sciences for the Management of Addiction. Written and edited by a group of internationally recognized addiction researchers, this book serves as a guide to bringing basic science knowledge to patient care.
Purpose: The purpose of the book, according to the editors "is to provide a needed link between advances in addiction science and innovations in clinical practice." The editors note that presently, even though there are now a number of adjunctive pharmacotherapies for addiction, many practitioners tend not use them and feel they are ineffective, in spite of evidence of efficacy. The editors hope to educate clinicians and show the utility of bringing basic science advances to the bedside.
Audience: The intended audience includes clinicians who treat patients with substance-related disorders.
Features: The first of the book's five sections deals with the basic neurobiology and genetics related to addictions. Pharmacotherapy is the focus of the second section with interesting chapters on plasticity, agonist treatments, and neuromodulation. Addiction is also related to social cognition, context, and motivational systems, and section three details the research findings on craving, impulse control, and affect. Addiction and social justice are related issues and section four summarizes public policies, ethical issues and practices related to intervention. The final section and chapter provides an overview of the processes involved in translating basic science to clinical practice as well as alternative pathways for improved diagnosis and treatment of these all too common disorders. Each chapter ends with relevant and timely references of the scientific literature.
Assessment: This is an excellent book that will help clinicians synthesize basic science information for application to improved clinical care of patients. I highly recommend it.
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Product Details

  • ISBN-13: 9780080449272
  • Publisher: Elsevier Science
  • Publication date: 7/12/2007
  • Edition description: New Edition
  • Pages: 512
  • Product dimensions: 1.13 (w) x 6.14 (h) x 9.21 (d)

Meet the Author

Peter M. Miller, Ph.D., is a clinical psychologist and Professor of Psychiatry and Behavioral Sciences in the Center for Drug and Alcohol Programs at the Medical University of South Carolina. He is Editor-in-Chief of the journal Addictive Behaviors and an experienced researcher and clinician in the field of alcohol use disorders.

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Table of Contents

TRANSLATION OF ADDICTIONS SCIENCE INTO PRACTICE:
UPDATE AND FUTURE DIRECTIONS

Preface

Section title: GENETICS AND NEUROSCIENCE

Chapter 1
The Interplay between Genotype and Gene Expression in Human Brain: What Can It Teach Us about Alcohol Dependence?

Chapter 2
Common Genetic Influences on Antisociality and Addictions: Implications for Clinical Science and Practice

Chapter 3
Opioids, Pain and Addiction: Cause and Consequence

Chapter 4
Imbalance between Neuroexcitatory and Neuroinhibitory Amino Acids Causes Craving for Ethanol: From Animal to Human Studies

Chapter 5
Cannabis and the Brain: Implications of Recent Research

Section title: PHARMACOTHERAPY

Chapter 6
The Plasticity of Alcohol Addiction Suggests Novel
Approaches to Pharmacological Intervention

Chapter 7
Pharmacotherapies for the Treatment of Alcohol Dependence: Current and On-the-Horizon

Chapter 8
Agonist Treatment for Stimulant Abuse and Dependence

Chapter 9
Topiramate-Induced Neuromodulation of Cortico-Mesolimbic Dopamine: Implications for the Treatment of Nicotine and Alcohol Dependence

Section title: PSYCHOLOGY AND SOCIOLOGY

Chapter 10
Advances in the Scientific Study of Craving for Alcohol and Tobacco

Chapter 11
Advances in the Treatment of Craving for Alcohol and Tobacco

Chapter 12
Cognitive, Affective and Motivational Effects of Smoking

Chapter 13
Therapeutic Outcome Research in the Addictions

Chapter 14
Implications of Research on Comorbidity for the Nature and Management of Substance Misuse

Chapter 15
The Role of Impulsive Personality Traits in the Initiation, Development and Treatment of Substance Misuse Problems

Chapter 16
Translational Research Involving Adolescent Substance Abuse

Section title: PRACTICE AND POLICY

Chapter 17
Dissemination of Evidence-Based Treatment into Substance Abuse Clinical Practice

Chapter 18
Alcohol Screening and Intervention in Medical and Surgical Settings

Chapter 19
Internet-Based Interventions for Alcohol, Tobacco and Other Substances of Abuse

Chapter 20
Alcohol Use among Undergraduate Students: From Brief
Interventions to Behavioral Economics

Chapter 21
Ethical and Policy Issues in the Translation of Genetic and Neuroscience Research on Addiction

Section Title: CONCLUSION

Chapter 22
Pathways to Innovation in Addiction Practice

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