The new edition of this successful monograph has been both updated and broadened. Since the previous (second) edition was published in 2000, the structures of the bacterial and eukaryotic ribosomes have been published, advancing our basic understanding of translation and mechanisms involving protein and RNA regulators. In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease. This book, with 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of disease.
The new edition has been both updated and broadened. Since the previous (second) edition was published in 2000, the structures of the bacterial and eukaryotic ribosomes have been published, advancing our basic understanding of translation and mechanisms involving protein and RNA regulators. In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease. Each reader will find out his own loved chapter . . . but all 30 chapters are an essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of disease.
The editors are to be congratulated on assembling an outstanding collection of contributions and contributors. While which chapters you choose to read will undoubtedly reflect your specific interests, I would encourage all to read the opening chapter written by the editors where they provide a highly readable review of the origins, mechanisms and targets of translational control and in so doing provide an important historical context for readers new to this 'hot' topic. Even if you already have the previous edition of Translational Control (as I do), then that should not inhibit you from buying this new edition; it is not just an updated version of the previous editions. The editors have introduced a significant number of new topics, some of which (for example, microRNAs) were not yet on the radar in 2000. Where topics have been covered in the previous edition(s), they have succeeded in their stated aim of getting chapters that are 'stimulating, edifying and authoritative' and in several cases have used different authors to 'ring the changes'.
Nature Cell Biology
Sequels often suffer from several shortcomings, including the monotonous repetition of ideas and the absence of the most recent advances. Readers of previous versions might have expected only a modestly updated and expanded version this time. But they are in for a surprise: all of the chapters are either substantially rewritten or are completely new and contributed by new authors. This guarantees that the book is up to date and offers fresh ideas on the future of translation research. Given the scope of this book, even the editors themselves warn that few 'will choose to read this volume from cover to cover, and certainly not in sequence.' I did, and I am glad. This book should not be missing from the shelves of any scholars of translation.
Society for General Microbiology Quarterly
This is a very useful volume for all those who know or suspect that transcriptional control of their favourite gene may not be the complete story.
Origins and Principles of Translational Control M.B. Mathews N. Sonenberg J.W.B. Hershey 1
Structure of the Bacterial Ribosome and Some Implications for Translational Regulation H.F. Noller 41
Structure and Function of the Eukaryotic Ribosome and Elongation Factors D.J. Taylor J. Frank T.G. Kinzy 59
The Mechanism of Translation Initiation in Eukaryotes T.V. Pestova J.R. Lorsch C.U.T. Hellen 87
Translation Initiation by Viral Internal Ribosome Entry Sites J.A. Doudna P. Sarnow 129
Translation Initiation via Cellular Internal Ribosome Entry Sites O. Elroy-Stein W.C. Merrick 155
Translation Termination, the Prion [PSI[superscript +]], and Ribosomal Recycling M. Ehrenberg V. Hauryliuk C.G. Crist Y. Nakamura 173
Coupled Termination-Reinitiation Events in mRNA Translation R.J. Jackson A. Kaminski T.A.A. Poyry 197
Mechanism of Translation Initiation in the Yeast Saccharomyces cerevisiae A.G. Hinnebusch T.E. Dever K. Asano 225
cis-Regulatory Sequences and trans-ActingFactors in Translational Control M.W. Hentze F. Gebauer T. Preiss 269
Regulation of mRNA Molecules by MicroRNAs K.A. Wehner P. Sarnow 297
The elF2[alpha] Kinases T.E. Dever A.C. Dar F. Sicheri 319
elF2[alpha] Phosphorylation in Cellular Stress Responses and Disease D. Ron H.P. Harding 345
Signaling to Translation Initiation B. Raught A.-C. Gingras 369
Translational Control in Cancer Development and Progression R.J. Schneider N. Sonenberg 401
Matters of Life and Death: Translation Initiation during Apoptosis S.J. Morley M.J. Coldwell 433
Translational Control in Metabolic Diseases: The Role of mTOR Signaling in Obesity and Diabetes S.C. Kozma S.H. Um G. Thomas 459
Translational Control of Synaptic Plasticity and Learning and Memory E. Klann J.D. Richter 485
Translational Control in Development B. Thompson M. Wickens J. Kimble 507
Protein Synthesis and Translational Control during Viral Infection I.J. Mohr T. Pe'ery M.B. Mathews 545
Regulation of Translation Elongation and the Cotranslational Protein Targeting Pathway T.P. Herbert C.G. Proud 601
Regulation of Termination and Recoding J.D. Dinman M.J. Berry 625
Nonsense-mediated mRNA Decay: From Yeast to Metazoans A. Jacobson E. Izaurralde 655
Localized Translation through Messenger RNA Localization E.R. Gavis R.H. Singer S. Huttelmaier 689
The Interface between mRNA Turnover and Translational Control C.I. Gonzalez C.J. Wilusz J. Wilusz 719
Translational Control in Plants and Chloroplasts D.R. Gallie 747
Mitochondrial Translation and Human Disease E.A. Shoubridge F. Sasarman 775
Translational Control in Prokaryotes P. Romby M. Springer 803
Noncanonical Functions of Aminoacyl-tRNA Synthetases in Translational Control P.L. Fox P.S. Ray A. Arif J. Jia 829
Therapeutic Opportunities in Translation J. Pelletier S. W. Peltz 855