Transmissible Diseases and Blood Transfusion: Proceedings of the Twenty-Sixth International Symposium on Blood Transfusion, Groningen, NL, Organized by the Sanquin Division Blood Bank Noord Nederland / Edition 1

Transmissible Diseases and Blood Transfusion: Proceedings of the Twenty-Sixth International Symposium on Blood Transfusion, Groningen, NL, Organized by the Sanquin Division Blood Bank Noord Nederland / Edition 1

by Cees Smit Sibinga
     
 

ISBN-10: 1402009860

ISBN-13: 9781402009860

Pub. Date: 09/30/2002

Publisher: Springer US

This book is the only published literature that comprehensively discusses all aspects of transfusion of transmissible diseases, the facts and the fiction. It is of paramount importance to all involved in the vein to vein chain of transfusion medicine. Session I addresses the basic blood safety aspects including the need for quality management, rational donor

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Overview

This book is the only published literature that comprehensively discusses all aspects of transfusion of transmissible diseases, the facts and the fiction. It is of paramount importance to all involved in the vein to vein chain of transfusion medicine. Session I addresses the basic blood safety aspects including the need for quality management, rational donor screening and the risks of blood transfusion for prenatal developmental toxicity. Session II addresses the gamma of transmissible infectious agents from bacteria through parasites and tick-borne agents to prions and the risks associated with xeno-transplantation and xenozoonoses. Session III sheds new light on NAT technology for detection of viral DNA and RNA, the cost-effectiveness of the alternatives to allogeneic blood transfusion. To what extent are genetic defects in stem cell genomic structures transmissible through transplantation and does questioning potential donors make any sense? Session IV addresses the preventive aspects on the future of transfusion medicine. Quantitative real-time PCR for Parvo B19 and advances in bacterial detection technology. The advancement from theory to practice of pathogen inactivation technology based on destruction of nucleic acids in cellular structures. Finally, a plea is made for co-operation and collaboration on a global scale, changing the pars pro toto phenomenon (the ships that pass in the night) for a totum pro parte, a true joining of forces to create a global network for blood safety and structured blood supply systems. Transmissible Diseases and Blood Transfusion is an important reference for all hematologists and researchers involved in transfusion medicine

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Product Details

ISBN-13:
9781402009860
Publisher:
Springer US
Publication date:
09/30/2002
Series:
Developments in Hematology and Immunology (closed) Series, #37
Edition description:
2002
Pages:
220
Product dimensions:
9.21(w) x 6.14(h) x 0.56(d)

Table of Contents

Moderators and Speakers
Foreword
IBlood Safety Aspects
Germs, Gels and Genomes. A Personal Recollection of 30 Years in Blood Safety Testing3
Quality Management for Blood Transfusion Services21
The Value of Donor Selection for Blood Safety23
Blood Donation: A Risk for Prenatal Developmental Toxicity?25
IITransmissible Diseases
Bacterial Contamination of Blood and Blood Products. An Underestimated Problem51
Parasites Transmitted by Blood Transfusion57
Prion Diseases and Blood Transfusion73
Tick-Borne Diseases: Recognized and Theoretical Risks Associated with Blood Transfusion83
Xeno-Transplantation and Xenozoonoses93
IIITransmissible Diseases
NAT Update: Where Are We Today?111
Cost-Effectiveness of Alternatives to Allogeneic Blood Transfusion; Reviewing the Available Evidence131
Hereditary Metabolic Diseases and Stem Cell Transplantation143
Detection of Disease: Possibilities and Limitations147
IVPreventative Aspects
Quantitative Real-Time PCR for Detection of Parvovirus B19 DNA in Blood Plasma for Plasma Screening167
Advances in Bacterial Detection Technology177
Pathogen Inactivated Blood Components: Advancing from Theory to Practice181
GCBS, ICBS and Other Initiatives - The Pars Pro Toto Phenomenon; Will There Ever Be a Totum Pro Parte?195
Index213

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