The Treatment of Opioid Dependence

Overview

The successor to Strain and Stitzer's Methadone Treatment for Opioid Dependence (Johns Hopkins, 1999), this expanded and updated volume reflects new developments in treatment protocols.

Methadone is still the most widely used medication for the treatment of opioid dependence, and the authors provide an extensive section on methadone treatment. Three chapters cover the pharmacology and clinical use of buprenorphine as well as the latest research on Naltrexone, Clonidine, and ...

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Overview

The successor to Strain and Stitzer's Methadone Treatment for Opioid Dependence (Johns Hopkins, 1999), this expanded and updated volume reflects new developments in treatment protocols.

Methadone is still the most widely used medication for the treatment of opioid dependence, and the authors provide an extensive section on methadone treatment. Three chapters cover the pharmacology and clinical use of buprenorphine as well as the latest research on Naltrexone, Clonidine, and Lofexidine. The volume also includes chapters on pain and prescription opioids as well as medication-free treatment and medically supervised alternatives to opioid substitute treatments, including withdrawal.

The Treatment of Opioid Dependence will be a valuable resource for methadone counselors, psychiatrists, psychologists, social workers, mental health nurses, and addiction counselors, as well as physicians interested in office-based buprenorphine treatment.

Johns Hopkins University Press

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Editorial Reviews

Doody's Review Service
Reviewer: Steve C. Lee, MD (Rush University Medical Center)
Description: This is an update of a book published in 1999 that provides a comprehensive review of the treatment of opioid dependence.
Purpose: The purpose is to review the extensive body of literature regarding opioid dependence to support clinical recommendations. There is also an aim to influence public policy by exhibiting the extensive body of research that supports the treatment of opioid dependence. The toll on society of opioid dependence, as with other substances of abuse, is substantial. Thus, a review of information regarding its treatment is warranted. This book does a superb job fulfilling this goal.
Audience: The main audience is the treatment community that works with patients suffering from opioid dependence and researchers interested in shedding more light on this disorder. As noted above, another target audience is government agencies that may potentially allocate support for opioid dependence treatment. The editors have conducted research in this area at Johns Hopkins for over two decades.
Features: The book provides a history of opioids and focuses on the emergence of methadone and naltrexone. Epidemiological data is presented well. There are chapters devoted to the various pharmacological therapies, namely methadone, buprenorphine, and naltrexone. Nonpharmacological treatments are also reviewed. The book covers treatment of adolescents and women, and comorbid medical and psychiatric disorders.
Assessment: This is an excellent resource. It is incredibly thorough and well organized. It is written with consistent clarity. The quality of the prose surpasses most books I've reviewed in the mental health arena. I recommend this book as the first resource to refer to for anyone with any questions or interest in the treatment of opioid dependence.
Journal of Addictive Diseases
A most welcome update of the 1999, Methadone Treatment of Opioid Dependence.

— Robert Maslansky

American Journal of Psychiatry

A clearly written book that deftly covers a wide array of issues. It belongs on the shelves of all clinicians who work with opioid dependent individuals.

Journal of Nervous and Mental Disease

This excellent volume... is written in clear language throughout and meant to be accessible to a wide range of readers—clinicians from counselors to academic physicians subspecializing in addictions, as well as students, administrators, and legislators... This book should be required reading for members of Congress.

Annals of Pharmacotherapy

An excellent source of information for practitioners whose primary focus is in the treatment of opioid-dependent patients as well as practitioners who are involved in the ancillary treatment of such patients.

British Journal of Psychiatry
This book is a mine of information and is extensively referenced... the single best book I have read on the treatment of opioid dependence and I have no hesitation in recommending it.

— Michael J. A. K. Kelleher

Annals of Pharmacotherapy - Robert C. Wolf

The clinical expertise of the authors is reflected in the detailed, yet highly practical, information presented.

British Journal of Psychiatry - Michael J. A. K. Kelleher

This book is a mine of information and is extensively referenced... the single best book I have read on the treatment of opioid dependence and I have no hesitation in recommending it.

Journal of Addictive Diseases - Robert Maslansky

A most welcome update of the 1999, Methadone Treatment of Opioid Dependence.

American Journal on Addictions - Mark J. Albanese

This well-written, easy-to-read book, with an unassuming title, is truly a tour-de-force. Analogous to the porridge in the Goldilocks story, it is neither too little nor too much, but just right!

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Product Details

  • ISBN-13: 9780801883033
  • Publisher: Johns Hopkins University Press
  • Publication date: 1/31/2006
  • Edition description: second edition
  • Edition number: 2
  • Pages: 576
  • Product dimensions: 6.00 (w) x 9.00 (h) x 1.18 (d)

Meet the Author

Eric C. Strain, M.D., and Maxine L. Stitzer, Ph.D., are professors in the Department of Psychiatry and Behavioral Sciences at the Johns Hopkins School of Medicine.

Johns Hopkins University Press

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Table of Contents

1 Introduction and historical overview 3
2 Regulatory, cost, and policy issues 18
3 Epidemiology of opioid use, abuse, and dependence 43
4 Pharmacology of methadone 59
5 Beginning and ending methadone dosing : induction and withdrawal 77
6 Methadone dose during maintenance treatment 89
7 Counseling and psychosocial services 119
8 Contingency management therapies 151
9 Practical issues of program organization and operation 178
10 Pharmacology of buprenorphine 213
11 Clinical use of buprenorphine 230
12 Office-based treatment with buprenorphine and other medications 253
13 Pharmacology and clinical use of LAAM, clonidine, and lofexidine 277
14 Pharmacology and clinical use of naltrexone 295
15 Medication-free treatment of opioid dependence 323
16 Medically supervised withdrawal as stand-alone treatment 346
17 Other substance use disorders : prevalence, consequences, detection, and management 365
18 Comorbid medical disorders 398
19 Comorbid psychiatric disorders 421
20 Specialty treatment for women 455
21 Treatment of persons under legal restrictions 485
22 Treatment of adolescents 497
23 Prescription opioid nonmedical use and abuse 508
24 Pain management in addicted patients 527
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