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Treatment of Primary Glomerulonephritis / Edition 2

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Overview


Primary glomerulonephritis is a common renal disease which may eventually lead to chronic renal failure. Treatment of glomerulonephritis is difficult. In particular, the use of glucocorticoids and immunosuppressive drugs require expertise, knowledge of the drugs, and careful monitoring of the patient. Paradoxically, the treatment of glomerulonephritis has become even more complicated in the recent years, after the introduction of a number of newer immunosuppressive drugs.

Extensively updated since publication of the first edition in 1997, this comprehensive yet concise guide to the treatment of even the most complex patients with primary glomerular diseases is full of practical information collected and organized in an easy-to-read manner. It encompasses the possible treatments of the different types of primary glomerulonephritis, including diseases intrinsic to the kidney of unknown or uncertain aetiology. Each of the main chapters is devoted to a single primary glomerulonephritis and follows a similar format to allow easy access of information.

The book contains not only an evidence-based review of the topic, but also practical recommendations from internationally recognized experts in the field.

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Editorial Reviews

Doody's Review Service
Reviewer: Muhammad Rafi Ud Din, MD (University of Kentucky College of Medicine)
Description: Appearing 12 years after the first edition, this revised, second edition of a book on glomerulonephritis keeps the same format of multiple short chapters.
Purpose: The goals are to offer comprehensive information and detailed discussion on the rationale, specifics, efficacy, toxicity, and limitations of current therapy as there has been tremendous development in the area of immune-modulating treatment options for various forms of primary glomerulonephritis since the last edition. This book responds well to the continued need for updated, well-organized information in this area where most guidelines and recommendations are still based on opinion.
Audience: It is written primarily for nephrology and glomerular disease specialists, as well as general internists and trainees caring for patients with primary glomerular diseases. A fresh view is being offered by a large number of international authors (authorities in their fields) and the newly assigned section editors.
Features: The book uses a standard design of black-and-white print with a colorful atlas in the middle to describe salient features of different primary glomerulonephritis with some immunofluorescence and electron micrographs. It provides a brief introduction to pathogenesis, etiology, epidemiology, and clinical presentation of glomerular diseases. It then details medical management, based on a critical review of the best available randomized clinical trials. In controversial areas, or the ones lacking definitive clinical studies, the authors provide their personal views and approach to treatment. Also, the first three chapters of the book describe the symptomatic therapy, pharmacology of glucocorticoids, and newer immune-modulating agents. The last chapter covers the less common form of glomerular diseases and recurrent glomerular diseases in the transplanted kidney. It provides diagnostic and treatment algorithms and tables of commonly used drugs. There are plenty of updated references, but placing them in the middle of sentences is rather distracting. The index is good but not complete. There are a few new topics, including transplant immunology and immunosuppression.
Assessment: This is an excellent addition to the currently available publications on medical management of glomerular diseases. It has its own niche because it offers in-depth discussions, critiques, and referenced coverage of key trials that influence decision making. It is rather comprehensive in its coverage and easy to read. However, given the lengthy discussion and lack of specific recommendations, it would be difficult for busy clinicians to use it as a quick reference. What I personally appreciate is the fact that it specifically tackles issues that are either controversial or not well understood.
From The Critics
Reviewer:This is an excellent addition to the currently available publications on medical management of glomerular diseases. It has its own niche because it offers in-depth discussions, critiques, and referenced coverage of key trials that influence decision making. It is rather comprehensive in its coverage and easy to read. However, given the lengthy discussion and lack of specific recommendations, it would be difficult for busy clinicians to use it as a quick reference. What I personally appreciate is the fact that it specifically tackles issues that are either controversial or not well understood.
Description:
Purpose:Appearing 12 years after the first edition, this revised, second edition of a book on glomerulonephritis keeps the same format of multiple short chapters.
Audience:The goals are to offer comprehensive information and detailed discussion on the rationale, specifics, efficacy, toxicity, and limitations of current therapy as there has been tremendous development in the area of immune-modulating treatment options for various forms of primary glomerulonephritis since the last edition. This book responds well to the continued need for updated, well-organized information in this area where most guidelines and recommendations are still based on opinion.
Features:It is written primarily for nephrology and glomerular disease specialists, as well as general internists and trainees caring for patients with primary glomerular diseases. A fresh view is being offered by a large number of international authors (authorities in their fields) and the newly assigned section editors.
Assessment:The book uses a standard design of black-and-white print with a colorful atlas in the middle to describe salient features of different primary glomerulonephritis with some immunofluorescence and electron micrographs. It provides a brief introduction to pathogenesis, etiology, epidemiology, and clinical presentation of glomerular diseases. It then details medical management, based on a critical review of the best available randomized clinical trials. In controversial areas, or the ones lacking definitive clinical studies, the authors provide their personal views and approach to treatment. Also, the first three chapters of the book describe the symptomatic therapy, pharmacology of glucocorticoids, and newer immune-modulating agents. The last chapter covers the less common form of glomerular diseases and recurrent glomerular diseases in the transplanted kidney. It provides diagnostic and treatment algorithms and tables of commonly used drugs. There are plenty of updated references, but placing them in the middle of sentences is rather distracting. The index is good but not complete. There are a few new topics, including transplant immunology and immunosuppression.
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Product Details

  • ISBN-13: 9780199552887
  • Publisher: Oxford University Press
  • Publication date: 6/22/2009
  • Series: Oxford Clinical Nephrology Series
  • Edition number: 2
  • Pages: 480
  • Product dimensions: 6.10 (w) x 9.10 (h) x 1.00 (d)

Meet the Author

Claudio Ponticelli graduated in Medicine at the University of Milan in 1961 before specialising in Endocrinology, Urology, and Nephrology. He worked as an assistant nephrologist at the University of Milan, before becoming Vice-Director of the Unit of Nephrology at Ospedale Maggiore, Milan in 1968, after which he became director first of the Unit of Nephrology, then of the Division of Nephrology in 1974 and finally director of the Department of Nephro-Urology in 2001. He retired in October 2003 and now works as a consultant at Scientific Institute Auxologico in Milan. His main fields of interest are primary and secondary glomerular diseases, renal transplantation, and immunosuppressive therapy. He has written more than 600 articles, and edited 22 books, as well as contributing over 80 chapters for international books.
Richard J. Glassock is an internationally recognized expert in the field of Glomerular Diseases and Clinical Nephrology. He has published over 400 original papers, books, monographs, book chapters and reviews in nephrology. He is the past-President of the American Society of Nephrology and the National Kidney Foundation. He is also past-Chairman of the American Board of Internal Medicine. In 1999 he was elected to Mastership in the American College of Physicians. He is also a member of the American Association of Physicians. He is the former Chair of the Department of Medicine and the University of Kentucky and Harbor-UCLA Medical Center. From 1967 to 1992 he was the Chief of Nephrology at Harbor-UCLA Medical Center. He was continuously funded by the NIH for extra-mural research grants from 1967 to 1987. He has lectured in over 90 countries throughout the world and has been a visiting professor at over 120 distinguished academic institutions throughout the world.

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