Treatment-Resistant Depression


The first book devoted to a challenging disorder that affects millions of people around the world. Essential reading for all psychiatrists who manage these patients.

Read More Show Less
... See more details below
Other sellers (Paperback)
  • All (9) from $36.57   
  • New (8) from $36.57   
  • Used (1) from $49.94   


The first book devoted to a challenging disorder that affects millions of people around the world. Essential reading for all psychiatrists who manage these patients.

Read More Show Less

Editorial Reviews

From the Publisher
“After all, this book is recommended for the youngpsychiatrist, who wants to read an easy introduction to thefascinating world of treatment of resistantdepression.”  (Acta Psychiatrica Scandinavica, 9November 2013)

“This is a monograph, which could be of great interest topsychiatrists managing patients with TRD. The chapters are writtenclearly, and the references are comprehensive andup-to-date.”  (Human Psychopharmacology: Clinical& Experimental, 6 November 2013)

“The editors should be congratulated for accomplishing theamazing feat of presenting so much information in such a compactbook. With an investment of just a few hours, readers can beupdated on a very complicated subject . . . The editors should becommended on detailing a variety of treatment options, includingnonpharmacological options, which other books fail toemphasize.”  (Doody’s, 23 August 2013)

Doody's Review Service
Reviewer: Aaron Plattner, MD (Pine Rest Christian Mental Health Services)
Description: Acknowledging the enormous impact of clinical depression and the difficulties in treating it, the editors discuss how to identify and manage patients with treatment-resistant depression.
Purpose: They strive to summarize the most recent scientific research and its implications. With the great need for the successful treatment of depression, this book is a needed addition to the field of psychiatry and it fulfills its stated purpose.
Audience: The editors identify this as "essential reading for all psychiatrists managing patients." Although the book will be used most by psychiatrists, primary care providers also would benefit from it, especially in locations with a shortage of psychiatrists. Experts write each chapter.
Features: The book begins with a definition of treatment-resistant depression and possible changes in the terminology to describe this condition more precisely. The second chapter reviews the genetic risk factors and genetic variations that impact treatment-resistant depression. The final section reviews the pharmacological and nonpharmacological options for treating patients with this form of depression. Each chapter begins with a summary, contains helpful graphics, and ends with a conclusion and pertinent references.
Assessment: The editors should be congratulated for accomplishing the amazing feat of presenting so much information in such a compact book. With an investment of just a few hours, readers can be updated on a very complicated subject. The first part of the book, which presents the background information of definitions and genetics, is particularly helpful in building a solid foundation for the following section illustrating treatment options. The editors should be commended on detailing a variety of treatment options, including nonpharmacological options, which other books fail to emphasize.
Read More Show Less

Product Details

  • ISBN-13: 9781119952909
  • Publisher: Wiley
  • Publication date: 4/22/2013
  • Edition number: 1
  • Pages: 228
  • Product dimensions: 5.04 (w) x 7.86 (h) x 0.45 (d)

Meet the Author

Professor Dr Kasper is Professor of Psychiatry and Chairmanof the Department of General Psychiatry at the Medical Universityof Vienna, Austria. He is Honorary Professor at the University ofHong Kong, China.  He concentrates on the biological bases ofmental disorders and their possible treatment approaches. He hasconducted studies in psychopathological as well as clinical areas.Dr Kasper is a frequent national and international speaker and isactively involved in research programmes studying depression,anxiety, psychosis, and dementia, authoring over 800 researchreports and reviews. Dr Kasper serves on the editorial boards ofnumerous learned journals, including European Archives ofPsychiatry and Neuroscience, European Psychiatry, and EuropeanNeuropsychopharmacology. He is Co-editor in-chief of theInternational Journal of Psychiatry in Clinical Practice.

Professor Montgomery was Professor of Psychiatry atImperial College, University of London until his retirement in 1996when he became Emeritus Professor of Psychiatry. He has greatbreadth of experience in the field of psychotropic medicine withseminal work in depression, anxiety disorders, suicide preventionand schizophrenia. He has published 26 books and more than 400papers. Professor Montgomery is editor of International ClinicalPsychopharmacology and was editor of EuropeanNeuropsychopharmacology for 20 years. He also serves on theeditorial board of numerous scientific journals.

Read More Show Less

Table of Contents

List of Contributors vii

Foreword ix

1 Definitions and Predictors of Treatment-resistant Depression1
Daniel Souery and William Pitchot

2 Treatment-resistant Depression: A Separate Disorder – ANew Approach 21
Hans-Jürgen Möller, Florian Seemüller, RebeccaSchennach and Ramesh K. Gupta

3 Genetics of Treatment-resistant Depression 43
Chiara Fabbri, Stefano Porcelli and Alessandro Serretti

4 Is There a Role for Switching Antidepressants inTreatment-resistant Depression? 91
Stuart Montgomery

5 The Role of Atypical Antipsychotics in Inadequateresponse andTreatment-resistant Depression 107
Siegfried Kasper and Elena Akimova

6 Lithium, Thyroid Hormones and Further Augmentation Strategiesin Treatment-resistant Depression 129
Robert Haußmann and Michael Bauer

7 The Role of Nonpharmacological Interventions inTreatment-resistant Depression 159
Thomas E. Schläpfer and Sarah Kayser

8 The Role of Psychotherapy in the Management ofTreatment-resistant Depression 183
Michael E. Thase

Index 209

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)