Trends and Future Perspectives in Peptide and Protein Drug Delivery / Edition 1

Trends and Future Perspectives in Peptide and Protein Drug Delivery / Edition 1

by Vincent Lee, Lee Lee
     
 

Peptide and protein drug delivery research has been moving at a brisk pace for over 10 years. Trends and Future Perspectives in Peptide and Protein Drug Delivery is a collection of snapshots of the major past and future developments in this exciting field as seen by over 20 invited speakers at a three-day conference on protein drug delivery held on September 2-4, 1993… See more details below

Overview

Peptide and protein drug delivery research has been moving at a brisk pace for over 10 years. Trends and Future Perspectives in Peptide and Protein Drug Delivery is a collection of snapshots of the major past and future developments in this exciting field as seen by over 20 invited speakers at a three-day conference on protein drug delivery held on September 2-4, 1993, in Kyoto, Japan. The wide-ranging topics covered included polymeric delivery systems for protein drugs, means of enhancement of protein drug transport, protein modification for improved pharmacokinetic/pharmacodynamic properties, targeting of peptide and protein drugs, and delivery of oligonucleotides and genes.

Product Details

ISBN-13:
9783718656417
Publisher:
Taylor & Francis
Publication date:
02/01/1995
Series:
Drug Targeting and Delivery Series
Edition description:
New Edition
Pages:
392
Product dimensions:
6.60(w) x 9.90(h) x 1.20(d)

Meet the Author

Table of Contents

Introduction to the Series
Preface
List of Contributors
Peptide and Protein Drug Delivery: Past, Present and Future3
Controlling Protein Diffusion in Hydrogels23
Poly(ortho esters) for the Pulsed and Continuous Delivery of Peptides and Proteins39
New Delivery Systems for Recombinant Proteins - Practical Issues from Proof of Concept to Clinic57
Penetration Enhancement of Peptide Drugs: Palmitoyl Derivatives of Insulin and a Transition-state Mimic Tripeptide Inhibitor of HIV Protease as a Potential Anti-AIDS Drug for Oral Administration71
Penetration Enhancement of Peptide and Protein Drugs by Electrochemical Means: Transdermal Iontophoresis83
Technological and Development Issues of Iontophoretic Transport of Peptide and Protein Drugs111
Enhancement of Transferrin Receptor-mediated Transcytosis for Transepithelial Protein Delivery135
Peptide Delivery across the Blood-Brain Barrier153
Improved Circulation Half-life of Proteins Using Deletion Mutants177
Pathophysiology of Reactive Oxygen Species: Analysis by Targeting SOD189
Targeting: From Proteins to Genes199
(Protein)-Targeted Delivery with Particulate Systems207
Vascular Targeting as a New Approach to the Therapy of Solid Tumors: Validation in a Mouse Tumor Model241
Recombinant DNA Vaccines: Use of Escherichia coli Envelope Proteins as Tools for Cellular and Molecular Targeting of Foreign Polypeptides in Bacteria and Protein Purification253
Targeting of Proteins in the Brain following Release from a Polymer273
Oligonucleotides as Potential Therapeutic Agents297
Liposomal DNA Delivery321
Gene Introduction into Animal Tissues337
Systemic Delivery of Recombinant Proteins by Genetically Engineered Myoblasts351
Index365

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