Tuberculosis / Edition 2

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This comprehensive clinical reference is edited by experts from the NYU-Bellevue Chest Service, which through its influence in tuberculosis care and education has been an integral part of the formation of the entire specialty of pulmonary medicine. The book draws on this extensive experience to present an authoritative account of the history, epidemiology, microbiology, immunology, clinical treatment, pharmacology, and prevention or control of tuberculosis. The book will serve as a definitive reference for specialists in pulmonary medicine, infectious disease, and public health. New to the Second Edition are more concise and focused chapters, new information on molecular biology from the genome project, and updated information especially for the epidemiology section.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Krista K. Graven, M.D.(University of Minnesota Medical School)
Description: This is a comprehensive review of the clinical, public health, and basic science aspects of tuberculosis. The first edition was published in 1996.
Purpose: The purpose is to provide a complete book on the topic by assembling chapters by leading authorities on every aspect of the disease. The second edition includes much needed updates on the changing epidemiology, basic research discoveries, and treatment options for resistant tuberculosis. These are worthy objectives and well met in this edition.
Audience: This book will serve as an excellent reference for both basic scientists and clinicians, including residents and fellows with a special interest in TB, and pulmonary, public health, and infectious disease specialists. The editors are leading authorities on this disease and have compiled an impressive group of authors to review each aspect of the disease.
Features: The book covers all aspects of the disease, including epidemiology, genomics and microbiology, the entire clinical spectrum, therapy and prevention. New to this edition are chapters reviewing directly observed therapy especially in relation to multidrug resistant TB, the newly sequenced genome of M. tuberculosis, updates on recent research pertaining to mechanisms of disease and the host response and discussion of current and future public health issues. The best aspects of this book are the extensiveness of the review and the new discussions related to treatment and epidemiology in light of emerging resistance and HIV disease. As with any book that attempts to cover basic science information, new data emerges quickly, making even new editions somewhat outdated.
Assessment: This book provides an excellent and complete review of tuberculosis and will serve as a definitive reference for anyone interested in this disease. The new information in this second edition justifies replacing the previous edition.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780781736787
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 9/28/2003
  • Edition description: Second Edition
  • Edition number: 2
  • Pages: 790
  • Sales rank: 1,355,519
  • Product dimensions: 8.80 (w) x 11.30 (h) x 1.70 (d)

Table of Contents


  2. The Writer’s Voice: Tuberculosis in the Arts 3
    Joan Reibman and Thomas Lennon
  3. Global Epidemiology of Tuberculosis 13
    Donald A. Enarson, Chen-Yuan Chiang, and John F. Murray
  4. Epidemiology of Tuberculosis in the United States 31
    C. Robert Horsburgh, Jr., Marisa Moore, and Kenneth G. Castro
  5. Molecular Epidemiology of Mycobacterium tuberculosis 47
    Barun Mathema and Barry N. Kreiswirth


  6. Comparative Genomics of the Mycobacterium tuberculosis Complex: Evolutionary Insight and Applications 65
    Roland Brosch, Sayera Banu, and Stewart T. Cole
  7. Genetic Diversity of the Mycobacterium tuberculosis Complex 75
    Marcel A. Behr
  8. Tuberculosis Latency in Humans 85
    Charles L. Daley
  9. Persistence and Drug Tolerance 101
    James E. Gomez and John D. McKinney
  10. The Cell Wall of Mycobacterium tuberculosis 115
    Dean C. Crick, Patrick J. Brennan, and Michael R. McNeil
  11. Mycobacterium tuberculosis Virulence: A Genetic Analysis 135
    Issar Smith
  12. Laboratory Diagnosis 163
    Bruce A. Hanna
  13. Novel Approaches to the Rapid Diagnosis of Tuberculosis 177
    Neil W. Schluger


  14. Immunodiagnosis 185
    Suman Laal
  15. The Role of the Nramp1 Gene in Mycobacterial Infections 193
    Ellen Buschman, Emil Skamene, and Erwin Schurr
  16. Phagocytosis and Toll-Like Receptors in Tuberculosis 203
    Larry S. Schlesinger
  17. Nitric Oxide in Tuberculosis 215
    Carl F. Nathan and Sabine Ehrt
  18. Animal Models of Tuberculosis 237
    JoAnne L. Flynn and John Chan
  19. Cell-Mediated Immune Response 251
    Timo Ulrichs and Stefan H. E. Kaufmann
  20. CD1 Response 263
    Peter A. Sieling and Robert L. Modlin
  21. Dendritic Cells 269
    Ralph M. Steinman and Thomas M. Moran
  22. Cytokine Response in Tuberculosis 285
    Rany Condos and William N. Rom
  23. Molecular Mechanisms of Human Immunodeficiency Virus/Tuberculosis Interaction in the Lung 301
    Yoshihiko Hoshino, Bindu Raju, and Michael Weiden
  24. Programmed Cell Death in Tuberculosis 309
    Joseph Keane and Hardy Kornfeld


  25. Pathology and Insights into Pathogenesis of Tuberculosis 323
    Jaishree Jagirdar and David Zagzag
  26. Pulmonary Tuberculosis 345
    Stuart M. Garay
  27. Imaging of Thoracic Tuberculous Infections 395
    Georgeann McGuinness and Ami N. Rubinowitz
  28. Miliary Tuberculosis 427 Stephen K. Baker and Jeffrey Glassroth
  29. Tuberculosis of the Brain, Meninges, and Spinal Cord 445
    Michael Henry and Robert S. Holzman
  30. Ocular Complications 465
    Dorothy Nahm Friedberg and Monica Lorenzo-Latkany
  31. Tuberculosis of the Head and Neck 477
    Andrew G. Sikora, Stephen G. Rothstein, Kenneth F. Garay, and Ruth Spiegel
  32. Mycobacterial Lymphadenitis 489
    Mark F. Sloane
  33. Pleural Tuberculosis 497
    Stephan L. Kamholz
  34. Cardiovascular Tuberculosis 509
    June E. S. Abadilla and Albert E. Heurich
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