Type 1 Diabetes: Etiology and Treatment

Overview

A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
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Paperback (Softcover reprint of hardcover 1st ed. 2003)
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Overview

A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
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Editorial Reviews

From the Publisher
"The first section provides a sound discussion of our understanding of the etiology of the disease, providing the reader with an excellent working knowledge to assess possible future prevention strategies. The clinical chapters are well organized, authored by known experts, and provide excellent summaries of cutting edge management. The final chapters devoted to islet transplantation and the relevant scientific issues are timely and enlightening...This entry in the Contemporary Endocrinology series represents a uniquely accessible overview of the current scientific and clinical frontiers relevant to type 1 diabetes mellitus. By providing an understanding of where immunological knowledge will likely lead and what current therapy should entail, this book provides an opportunity for both clinical and research specialists to better understand each other's fields." -Doody's Health Sciences Book Review Journal

"A highly recommended book that is hard to put down. It was easy to read, detailed, and extremely useful in a practical sense for clinicians." - E-Streams

"The complex interactions of genetics, autoimmunity, and insulin secretion are covered thoroughly and would gainfully challenge most experts in the field." -Annals of Internal Medicine

Doody's Review Service
Reviewer: Robert Jay Sobel, M.D.(Northwestern University Feinberg School of Medicine)
Description: This book represents a remarkably complete overview of the state-of-the-art in both the clinical management of type 1 diabetes and the ongoing research working towards improved treatment, prevention, and cure.
Purpose: According to the author, the aim of this book is to make available a fusion of the contemporary investigational and practical issues of this disease. For those involved in the research and treatment of patients with type 1 diabetes, this represents a uniquely accessible way to make sure they have an up-to-date, working knowledge of a wide-ranging spectrum of issues.
Audience: This book is appropriate for endocrinologists both in practice and in training, and researchers involved in the many areas that interface with type 1 diabetes.
Features: The first section provides a sound discussion of our understanding of the etiology of the disease, providing the reader with an excellent working knowledge to assess possible future prevention strategies. The clinical chapters are well organized, authored by known experts, and provide excellent summaries of cutting edge management. The final chapters devoted to islet transplantation and the relevant scientific issues are timely and enlightening. All chapters are well referenced and overlap of issues is kept to a reasonable minimum. Minor typographical errors are present at low level.
Assessment: This entry in the Contemporary Endocrinology series represents a uniquely accessible overview of the current scientific and clinical frontiers relevant to type 1 diabetes mellitus. By providing an understanding of where immunological knowledge will likely lead and what current therapy should entail, this book provides an opportunity for both clinical and research specialists to better understand each other's fields.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781617372582
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 11/9/2010
  • Series: Contemporary Endocrinology Series
  • Edition description: Softcover reprint of hardcover 1st ed. 2003
  • Edition number: 1
  • Pages: 593
  • Product dimensions: 7.00 (w) x 10.00 (h) x 1.23 (d)

Table of Contents

I. Etiology

Epidemiology of Type 1 Diabetes

Janice S. Dorman, Ronald E. LaPorte, and Thomas J. Songer

Genetics of Type 1 Diabetes

Massimo Pietropaolo and Massimo Trucco

Prediction and Prevention of Type 1 Diabetes

Aristides K. Maniatis and George S. Eisenbarth

Molecular Biology of b-Cell Destruction by Autoimmune Processes

Åke Lernmark and Choon Hee Chung

Type 1 Diabetes in Autoimmune Syndromes

Tiinamaija Tuomi and Jaakko Perheentupa

The Metabolic Basis of Insulin Secretion

Nicolai M. Doliba and Franz M. Matschinsky

Prevention and Correction of Hypoglycemia: Relevance to Type 1 Diabetes

Philip E. Cryer

Nonautoimmune Forms of Diabetes: Neonatal Diabetes, DIDMOAD-Wolfram Syndrome, and Related Syndromes

Timothy G. Barrett

II. Treatment of Type 1 Diabetes

Diabetic Ketoacidosis

Ram K. Menon and Mark A. Sperling

Insulin Regimens for Type 1 Diabetes

Baiju R. Shah and Bernard Zinman

Relationship Between Metabolic Control and Complications in Diabetes: Therapeutic Implications of the Diabetes Control and Complications Trial

Saul Genuth

Open- and Closed-Loop Insulin Delivery Systems and Glucose Sensors

John C. Pickup

Living with Diabetes: Educating the Patient and Family with Type 1 Diabetes

Jean Betschart Roemer and Linda Siminerio

Nutritional Management in Type 1 Diabetes

Christine A. Beebe

III. Special Management Issues in Type 1 Diabetes

Special Problems and Management of the Child Less than 5 Years of Age

Nadia Tubiana-Rufi and Paul Czernichow

The Preadolescent Child with Type 1 Diabetes

William V. Tamborlane, Elizabeth A. Boland, and Margaret Grey

The Adolescent with Type 1 Diabetes

George A. Werther, Fergus J. Cameron, and John M. Court

Hypoglycemia in Type 1 Diabetes

Stephanie A. Amiel and Krystyna Matyka

Pregnancy and Type 1 Diabetes

Erica M. Sommermann, Erin K. Van Meter, and Lois Jovanovic

Surgery for the Patient with Type 1 Diabetes

Adrian Vella and Robert A. Rizza

IV. Long-Term Complications of Type 1 Diabetes

Biochemistry and Molecular Biology of Diabetic Complications

Kenya Sakamoto and Michael Brownlee

The Eye: Diabetic Retinopathy/Ophthalmopathy

David Kent and Peter A. Campochiaro

The Kidney: Diabetic Nephropathy

Abhay Vats and Frederick DeRubertis

Diabetic Peripheral and Autonomic Neuropathy

Eva L. Feldman, Martin J. Stevens, and James W. Russell

The Diabetic Foot

David L. Steed

Atherosclerosis in Type 1 Diabetes

Wael Emad Eid, Siripoom McKay, Finnbogi Karlsson, and Alan J. Garber

Cutaneous Complications of Type 1 Diabetes

Jean L. Bolognia and Irwin M. Braverman

Infection and Diabetes

Nirmal Joshi

Pancreas Transplantation

R. Paul Robertson

Islet Transplantation

Thierry Berney, Norma Sue Kenyon, Rodolfo Alejandro, Luca Inverardi, Daniel H. Mintz, and Camillo Ricordi

b-Cell Replacement Therapy for Type 1 Diabetes

Shimon Efrat

Islet Growth Factors

Rupangi C. Vasavada, Adolfo Garcia-Ocaña, Karen K. Takane, Ana Cebrian, Juan Carlos Lopez-Talavera, and Andrew F. Stewart

Index

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