Type 1 Diabetes: Etiology and Treatment / Edition 1

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Overview

A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
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Editorial Reviews

Doody's Review Service
Reviewer: Robert Jay Sobel, M.D.(Northwestern University Feinberg School of Medicine)
Description: This book represents a remarkably complete overview of the state-of-the-art in both the clinical management of type 1 diabetes and the ongoing research working towards improved treatment, prevention, and cure.
Purpose: According to the author, the aim of this book is to make available a fusion of the contemporary investigational and practical issues of this disease. For those involved in the research and treatment of patients with type 1 diabetes, this represents a uniquely accessible way to make sure they have an up-to-date, working knowledge of a wide-ranging spectrum of issues.
Audience: This book is appropriate for endocrinologists both in practice and in training, and researchers involved in the many areas that interface with type 1 diabetes.
Features: The first section provides a sound discussion of our understanding of the etiology of the disease, providing the reader with an excellent working knowledge to assess possible future prevention strategies. The clinical chapters are well organized, authored by known experts, and provide excellent summaries of cutting edge management. The final chapters devoted to islet transplantation and the relevant scientific issues are timely and enlightening. All chapters are well referenced and overlap of issues is kept to a reasonable minimum. Minor typographical errors are present at low level.
Assessment: This entry in the Contemporary Endocrinology series represents a uniquely accessible overview of the current scientific and clinical frontiers relevant to type 1 diabetes mellitus. By providing an understanding of where immunological knowledge will likely lead and what current therapy should entail, this book provides an opportunity for both clinical and research specialists to better understand each other's fields.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780896039315
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 6/28/2003
  • Series: Contemporary Endocrinology Series
  • Edition description: 2003
  • Edition number: 1
  • Pages: 593
  • Product dimensions: 6.90 (w) x 10.10 (h) x 1.30 (d)

Table of Contents

1 Epidemiology of type 1 diabetes 3
2 Genetics of type 1 diabetes 23
3 Prediction and prevention of type 1 diabetes 55
4 Molecular biology of [Beta]-cell destruction by autoimmune processes 71
5 Type 1 diabetes in autoimmune syndromes 93
6 The metabolic basis of insulin secretion 115
7 Prevention and correction of hypoglycemia: relevance to type 1 diabetes 145
8 Nonautoimmune forms of diabetes: neonatal diabetes, DIDMOAD-Wolfram syndrome, and related syndromes 163
9 Diabetic ketoacidosis 183
10 Insulin regimens for type 1 diabetes 199
11 Relationship between metabolic control and complications in diabetes: therapeutic implications of the diabetes control and complications trial 215
12 Open- and closed-loop insulin delivery systems and glucose sensors 233
13 Living with diabetes: educating the patient and family with type 1 diabetes 249
14 Nutritional management in type 1 diabetes 261
15 Special problems and management of the child less than 5 years of age 279
16 The preadolescent child with type 1 diabetes 293
17 The adolescent with type 1 diabetes 307
18 Hypoglycemia in type 1 diabetes 321
19 Pregnancy and type 1 diabetes 345
20 Surgery for the patient with type 1 diabetes 361
21 Biochemistry and molecular biology of diabetic complications 375
22 The eye: diabetic retinopathy/ophthalmopathy 393
23 The kidney: diabetic nephropathy 409
24 Diabetic peripheral and autonomic neuropathy 437
25 The diabetic foot 463
26 Atherosclerosis in type 1 diabetes 473
27 Cutaneous complications of type 1 diabetes 485
28 Infection and diabetes 501
29 Pancreas transplantation 517
30 Islet transplantation 529
31 [Beta]-cell replacement therapy for type 1 diabetes 553
32 Islet growth factors 561
Index 579
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