Understanding Breast Cancer Genetics

Overview

This book examines a fearsome disease that strikes one in eight women in the United States. A diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. In this book Barbara T. Zimmerman, a scientist whose background is in cellular and molecular biology, helps general readers understand the genetic bases of both sporadic and ...
See more details below
Other sellers (Paperback)
  • All (5) from $1.99   
  • Used (5) from $1.99   
Sending request ...

Overview

This book examines a fearsome disease that strikes one in eight women in the United States. A diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. In this book Barbara T. Zimmerman, a scientist whose background is in cellular and molecular biology, helps general readers understand the genetic bases of both sporadic and inherited breast cancers. In clear, concise language she guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. She describes how both forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. The issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling are covered too. Dr. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy.
Read More Show Less

Editorial Reviews

Doody's Review Service
Reviewer: Devanshi Patel, MS (Evanston Northwestern Healthcare)
Description: This title is a succinct 117-page book that provides readers with a brief summary of issues pertinent to understanding breast cancer. The book is made up of six chapters that offer a vast amount of information on epidemiology, etiology, genetics, prevention, treatment, and research related to breast cancer. It also includes an appendix that lists organizations involved with breast cancer, a glossary, and an index. There is also a section on notes where Dr. Zimmerman highlights key points that she was not able to make within the context of the book.
Purpose: Although it is important to keep in mind that breast cancer is a multifactorial disease that involves complex interactions between both genes and the environment, the current climate of genetic research has made it possible to achieve great strides in the elucidation of genetic factors related to breast cancer. These discoveries have put forth a plethora of information that warrants consolidation. With her book entitled, Understanding Breast Cancer Genetics, author Barbara T. Zimmerman, PhD attempts to do just this.
Audience: This book would be a valuable and quick read for any health care professional who is new to the field of clinical oncology.
Features: While I think this book has many strengths, one of which is the amalgamation of a breadth of information, I do have a couple of suggestions that I would like to offer. First, although the book does go into great detail about hereditary breast and ovarian cancer syndrome, and references Li-Fraumeni syndrome and ataxia telangiectasia, mention of the other hereditary syndromes that are associated with an increase risk of breast cancer should have also been included. Also, the title of the book should exclude the word genetics. This may be able to capture a wider audience and be more reflective of the content of the book. Even though Dr. Zimmerman dedicates two full chapters to genetics and highlights genetics throughout the book where it is relevant, this book contains a lot of non-genetic information that is quite worthwhile. It would be a shame if someone were to dismiss it based on the assumption that it is solely dedicated to the genetics of breast cancer.
Assessment: I think many authors that attempt this nature of summarization may have difficulty in enticing most readers to peruse their book from cover to cover. However, I think Dr. Zimmerman accomplishes this. She makes this book an easy read by not only offering complex information in simple terms but also by including historical information that keeps the reader captivated.

2 Stars from Doody
Read More Show Less

Product Details

  • ISBN-13: 9781578065790
  • Publisher: University Press of Mississippi
  • Publication date: 1/13/2004
  • Series: Understanding Health and Sickness Series
  • Pages: 128
  • Product dimensions: 5.40 (w) x 8.40 (h) x 0.50 (d)

Table of Contents

Acknowledgments
Introduction
1 Who Gets Breast Cancer? 3
2 What Is Breast Cancer? 9
3 The Roles of Genes Versus Inheritance 26
4 The Roles of BRCA1, BRCA2, and Other Cancer Genes 42
5 Issues in Prevention and Control of Breast Cancer 52
6 Breast Cancer Research 79
Appendix 91
Notes 97
Glossary 99
Index 111
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)