Vaccines: Expert Consult / Edition 5

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Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination—from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety…recommendations for vaccine use, with rationales…data on the impact of vaccination programs on morbidity and mortality…and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most!

• Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues.
• Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage.
• Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies.
• Analyses the cost-benefit and cost-effectiveness of vaccines.
• Discusses the proper use of immune globulins and antitoxins.
• Illustrates concepts and objective data with approximately 600 tables and figures.

• Includes access to a companion web site offering the complete contents of the book – fully searchable – for rapid consultation from anyplace with an Internet connection.

Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Archana NMI Chatterjee, MD PhD(Creighton University)
Description: This is arguably the world's best book on vaccines. Beginning with general aspects of vaccination, it provides comprehensive, authoritative information on individual vaccine-preventable diseases, licensed vaccines, vaccines in development, new vaccination strategies, vaccination of special populations such as healthcare workers, and public health and regulatory issues. The previous edition was published in 2004.
Purpose: It is intended as a reference for all who are interested in vaccines for the prevention of disease. It is sorely needed as the field of vaccinology constantly evolves with new vaccines being developed for emerging infections and vaccination strategies being deployed against noninfectious diseases.
Audience: As a reference, it may be used by anyone interested in learning more about vaccines in general or in obtaining detailed information about a specific vaccine. The book could potentially be of value to graduate and postgraduate students in the health sciences, medical residents, fellows in immunology and infectious diseases, practitioners in primary care, infectious diseases, immunology, public health, occupational health, travel medicine, and healthcare epidemiology. The authors are renowned experts in the field.
Features: All aspects of vaccination are covered: history; vaccine development; details of clinical features, microbiology, pathogenesis, diagnosis, treatment, epidemiology and public health ramifications of each vaccine-preventable disease; an in-depth discussion of licensed vaccines and those in development, including immunogenicity, efficacy, safety, stability, duration of immunity, recommendations for use, and public health impact; and vaccination of special populations such as the immunocompromised. The book is richly populated with tables, graphs, maps, and color illustrations that complement the text. This edition comes with access to an online version. The appendix of web sites with information about immunization has been updated. It is hard to find any shortcomings.
Assessment: In the rapidly evolving field of vaccinology, this new edition is invaluable. There are truly no comparable books. The closest, perhaps, is Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book), 11th edition, by the National Immunization Program, Centers for Disease Control and Prevention (Public Health Foundation, 2009), but it does not provide much of the detailed information that is available in Vaccines. This is the premier reference for all aspects of vaccinology.
From the Publisher
BMA Book Awards 2008 - Highly Commended "With a broad view, this book draws together the many strands relevant to Immunisation and is a worthy addition to a library and specialist users who already have knowledge of country specific policy."

"For anyone wishing to know everything important about existing vaccines, this book provides an indispensable source of authoritative information" Immunology News - February 2009

David I. Bernstein
In this third edition, the editors have provided an even more comprehensive review of the subject of vaccines than previously (the second edition appeared in 1994). The editors include everything from manufacturing processes to general immunization practices with additional discussions for each vaccine. The preface does not contain a description of the purpose, but this book is clearly meant to provide a comprehensive description of vaccines. This is definitely a worthy objective, especially in this era when biotechnology is churning out new candidate antigens, pharmaceutical interest is high, and vaccines have taken on a more political dimension. The objectives are certainly met and exceeded; timely discussions for each vaccine are provided, and excellent introductory chapters in immunology, vaccine manufacturing, and general immunization practices are included. The book is aimed at several audiences. The chapters are complete enough to provide an excellent introduction to each topic for the student, resident, or practitioner but also detailed enough to add to the knowledge of infectious disease experts. There is no doubt as to the qualification of the editor and most of the contributors. The book contains a comprehensive review of vaccines written by authorities in the field. Several chapters serve as an excellent introduction to the field of vaccinology. The inclusion of chapters on manufacturing process, quality assurance, regulatory issues, legal issues, and new technologies, in addition to reviews of all licensed vaccines, all contribute to make this an excellent text. Each chapter is well illustrated and referenced and provides an introduction to the pathogen and clinicaldisease manifestations preceding a comprehensive review of the vaccine. The average reference list must approach 300. This is a superbly written and illustrated review of vaccines. This edition is considerably enlarged with important new additions reviewing immunology, production practices, new technologies, etc., without compromising the in-depth discussion of each licensed vaccine. Chapters on immunization for healthcare workers, for foreign travel, and immunization of the immunocompromised further enhance the practical aspect of this edition. This book will be a valuable addition to the library of both the novice and the expert in the field of vaccinology. There is no other book that covers the field of vaccine as thoroughly or enjoyably as this one.
Mark R. Schleiss
This is the second edition of a useful book that describes the vaccines available in current clinical practice. Since the publication of the first edition 6 years ago, there has been considerable progress in the field, in particular in the development of new vaccines for H. influenzae disease. These new areas of vaccine development are nicely summarized in the new edition. The role of sociological and political influences on vaccine development, delivery, and utilization is intelligently considered. The purpose is to serve as a guide for the clinician. Scholarly in overview and detailed in historical perspective, the book nevertheless manages to retain a high degree of clinical relevance. There is some awkwardness as the book transitions from descriptions of those vaccines currently in routine use to those that have only recently been developed. Some sections of the book, particularly the sections detailing the development of poliomyelitis vaccines, also suffer from some repetitiveness. However, the overall impression is of a book that should serve as a comprehensive reference volume that not only chronicles the history of vaccine development to date, but also anticipates the imminent release and clinical use of new vaccines such as the hepatitis A vaccine and acellular pertussis vaccines. The authors suggest that this book is directed at the practitioner, and largely this is the case. A most helpful feature of the book is the appendix that provides ""at a glance"" summaries of current ACIP recommendations, individual state immunization requirements, and a guide to contraindications and precautions to immunizations. This book would make an outstanding and practical additionto the personal library of any provider of primary care. It will also have wide value to basic scientists interested in ""real-world"" clinical and political overviews of vaccine usage and development as well as to students of the history of medicine.
Journal of the American Medical Association
With its extensive index, this well illustrated book is an invaluable tool and reference text that belongs in all medical libraries. It will please all who work with vaccines, showing that, while vaccines account for only one percent of the drug market, they give much health to humankind.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781416036111
  • Publisher: Elsevier Health Sciences
  • Publication date: 2/7/2008
  • Edition description: Older Edition
  • Edition number: 5
  • Pages: 1748
  • Product dimensions: 9.00 (w) x 11.10 (h) x 2.70 (d)

Table of Contents

Section 1: General aspects of vaccination

1. A Short History of Vaccination, Stanley L. Plotkin, Susan L. Plotkin
2. The Immunology of Vaccination, Claire-Anne Siegrist
3. The Vaccine Industry, Gordon Douglas, Vijay Samant
4. Vaccine Manufacturing, James Robinson
5. Immunologic Adjuvants, Fred Vogel, Stanley Hem
6. Vaccine Additives and Manufacturing Residuals in the United States: Licensed Vaccines, Theresa Finn, William Egan
7. General Immunization Practices, William Atkinson, Larry Pickering, & Andrew Kroger

Section 2: Licensed vaccines

8. Anthrax Vaccine, Phillip S Brachman, Arthur M Friedlander, John Grabenstein
9. Cholera Vaccine, Carol Tacket, David Sack
10. Diphtheria Toxoid, Melinda Wharton
11. Haemophilus influenzae Vaccine, Aruna Chadran, James P Watt, Mathuram Santosham
12. Hepatitis A Vaccine, Beth Bell, Steve Feinstone & Tony Fiore
13. Hepatitis B Vaccine, Eric Mast, Susan Goldstein, John Ward
14. Human Papillomavirus (HPV) Vaccine, John T Schiller
15. Influenza Vaccine (Inactivated), Nancy Cox, Carolyn Bridges, Roland Levandowski, Jackie Katz
16. Influenza Vaccine (Live), Robert B Belshe, Robert E Walker, Jeffrey J. Stoddard, Paul Mendleman
17. Japanese Encephalitis Vaccines, Scott Halstead, Julie Jacobson
18. Measles Vaccine, Peter M Strebel, Mark Papania
19. Meningococcal Vaccines, Dan M Granoff
20. Mumps Vaccine, Stanley Plotkin, Steven Rubin
21. Pertussis Vaccine, Kathryn Edwards, Michael Decker
22. Plague, Diane Williamson, Richard Titball, A J Simpson
23. Pneumococcal Conjugate Vaccine, Steve Black, Henry Shinefield, Juhani Eskola, Cynthia Whitney
24. Pneumococcal Polysaccharide, Kathy Neuzil, Lisa Jackson
25. Poliovirus Vaccine (Inactivated), Stanley Plotkin, Emmanuel Vidor
26. Poliovirus Vaccine (Live), Roland Sutter
27. Rabies Vaccine, Stanley Plotkin, Hilary Koprowski, Charles Rupprecht
28. Rotavirus Vaccine, Paul Offit, Fred Clark, Dick Ward
29. Rubella Vaccine, Stanley Plotkin, Susan Reef
30. Smallpox and Vaccinia, Donald A. Henderson, Lu Borio, John Grabenstein
31. Tetanus Toxoid, Steve Wassilak, Walter Orenstein
32. Tick-Borne Encephalitis Virus Vaccine, Noel Barrett, Hartmut Josef Ehrlich
33. Tuberculosis, Kimberly C Smith, Jeffrey R Starke, Ian M Orme, James Kaper
34. Typhoid Fever Vaccine, Myron M Levine
35. Varicella Vaccine, Anne A. Gershon, Michiaki Takahashi, Jane Seward
36. Yellow Fever Vaccine, Tom Monath, Dirk Teuwen, Marty Cetron
37. Zoster Vaccine, Myron Levin
38. Combination Vaccines, Michael Decker, H. Bogaerts, K. Edwards

Section 3: Vaccines in development and new vaccine strategies

39. Adenovirus Vaccine, Greg Gray, Charlotte Gaydos
40. Biodefense and Special Pathogen Vaccines, LTC Philip R. Pittman, Stanley Plotkin
41. Therapeutic Cancer Vaccines, Neil Berinstein, David Spaner
42. Cytomegalovirus Vaccine, Stanley Plotkin
43. Dengue Vaccine, Scott Halstead, Duane Gubler
44. Diarrhea Caused by Bacteria, James P Nataro
45. Ebola Vaccine, Gary Nabel, Peter B. Jahrling
46. Epstein-Barr Virus Vaccine, Denis Moss, Joanne Davis
47. Hepatitis C Vaccine, Michael Houghton
48. Hepatitis E Vaccine, Robert Purcell, Suzanne Emerson
49. Herpes Simplex Virus Vaccine, Lawrence Stanberry
50. Human Immunodeficiency Virus (HIV), Marc Girard, Koff
51. Lyme Disease Vaccine, Allen C Steere
52. Malaria Vaccine, Filip Dubovsky, Elissa Malkin
53. Noninfectious Disease Vaccines, George Siber, A Fattom (NABI)
54. Parainfluenza and Respiratory Syncytial Virus Vaccines, Ruth Karron
55. Parasitic Disease Vaccines, Peter Hotez, Jeff Bethony
56. Severe Acute Respiratory Syndrome (SARS) Vaccine, Albert Osterhaus
57. Staphylococcus Vaccine, Robert Daum
58. Streptococcus Group A Vaccine, Karen Kotloff
59. Streptococcus Group B Vaccine, Carol Baker, C. Mary Healy
60. New Vaccine Strategies, Ronald W Ellis
61. Delivery Systems, Bruce Weniger, Mark Papania
62. Vectors, Gary Nabel

Section 4: Vaccination of special groups

63. Vaccination in the Immunocompromised Host, Per Ljungman
64. Vaccination of Human Immunodeficiency Virus-Infec ted Persons, William J Moss, Neal A Halsey
65. Vaccines for International Travel, Elizabeth Day Barnett, Phyllis E. Kozarsky, Robert Steffen
66. Vaccines for Health Care Workers, David J Weber, Ray Strikas, Mike Decker or Bill

Section 5: Public health and regulatory issues

67. Immunization in the United States, Walter Orenstein, Lance Rodewald, Alan Hinman, Anne Schuchat
68. Immunization in Europe, David Salisbury
69. Immunization in Asia, Theodore Tsai, Zhi Yi Xu
70. International Immunization, Steve Hadler, Felicity Cutts, Vance Dietz, Steve Wiersma
71. Community Immunity, Paul Fine, Kim Mulholland
72. Economic Analyses of Vaccine Policies, Mark Miller, Alan Hinman
73. Regulation and Testing of Vaccines, Norman Baylor, Karen Midthun
74. Safety of Immunizations, Paul Offit, Robert L Davis, Deborah Gust
75. Legal Issues, Emily Marcus Levine, Geoffrey S Evans, Elizabeth Saindon
76. Ethics, Arthur Caplan, Jason L Schwartz


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