Veterinary Hematology and Clinical Chemistry / Edition 2

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Veterinary Hematology and Clinical Chemistry, Second Edition is a well-illustrated, user-friendly reference on veterinary laboratory diagnostic techniques and interpretation. Covering both hematology and chemistry for a wide range of species, including birds, reptiles, amphibians, and fish, the book provides an overview of these critical veterinary skills. This Second Edition includes many revisions and additions, including new chapters on molecular diagnostics of hematologic malignancies and lipid pathology, updates to reflect advances in diagnostic instrumentation and capabilities, significant revisions to the data interpretation chapter to provide introductory guidance, and current information on immunodiagnostics and laboratory diagnostics of renal, endocrine, and calcium metabolic pathologies.

Beginning with the basic principles of laboratory testing and diagnosis, the book moves into in-depth information on hematology and chemistry of common domestic and non-domestic species. Clinical case presentations, supplying case data and offering narrative discussions to promote skills, have been expanded and incorporated into the body of the book. Packed with useful information for veterinary students, technicians, pathologists, and researchers, Veterinary Hematology and Clinical Chemistry is an essential addition to any veterinary library.

"Written by twelve leading experts in veterinary pathology, this book provides a core introduction to lab medicine and clinical chemistry including sample collection techniques, recognition of pathology, and interpretation of findings."

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Editorial Reviews

Doody's Review Service
Reviewer: Anne Barger, DVM, MS (University of Illinois College of Veterinary Medicine)
Description: This veterinary clinical pathology book uses excellent figures and a good number of relevant clinical cases in its presentation of the material.
Purpose: The purpose is to provide a readable resource for veterinary laboratory diagnostics.
Audience: The audience is veterinary practitioners and veterinary students, but the book is also an excellent reference for veterinary clinical pathology residents and clinical pathologists. The authors are highly respected in the field.
Features: This is a thorough review of all aspects of clinical hematology and chemistry, including laboratory methods and current technology. The book has an extensive collection of clinical cases along with images, data, and thorough explanations of pathophysiology.
Assessment: Most other general clinical pathology books use an outline format, while this one presents the information in text format, along with many color images. This edition includes new sections on molecular diagnostics of hematologic malignancies and lymphoproliferative disorders and has expanded some topics, such as acid-base disorders, into their own chapters.
From the Publisher

“It will also prove to be of benefit for clinical pathology residents and specialists who deal with nondomestic and exotic species.”  (Journal of The American Veterinary Medical Association, 15 March 2013)

“I found the self-study part really useful . . . A great investment to help you decipher the mysteries of the lab reports.”  (Tomorrow's vets, 1 September 2013)

“This book cannot be highly recommended enough to the vet student, and I believe it is just as indispensable for the veterinary surgeon in practice – no mean feat for a textbook.”  (Veterinary Practice News, 1 September 2013)

“In summary, this is a comprehensive text with a strong practical and clinical focus and. It’s clearly written and supplemented by generous numbers of quality images . . . This book has a small animal bias and as such will be of greatest interest to small animal clinicians, but will also be valuable to clinicians seeing mixed practice, or delving into providing small mammal or exotic pet clinical pathology.”  (Australian Veterinary Journal, 9 September 2013)

“The second edition certainly fulfils its stated objective and is a valuable resource for its targeted audience.  It will also prove be benefit for clinical pathology residents and specialists who deal with nondomestic and exotic species.”  (Journal of the American Veterinary Medical Association, 15 March 2013)

“Overall, I think this book is well written and beautifully presented.  It appears to bridge the gap between undergraduate and postgraduate readers and covers all the species likely to be encountered in mixed veterinary practice.”  (Veterinary Record, 16 March 2013)

"Mary Anna Thrall,'s VETERINARY HEMATOLOGY AND CLINICAL CHEMISTRY, 2ND EDITION (9780813810270, $99.99) offers a key to understanding veterinary laboratory diagnostic techniques and interpretation and covers hematology and chemistry for a range of species to include fish, amphibians and birds. This second edition includes many revisions and additions, from new chapters on molecular diagnostics of hematologic malignancies to updates in advancements on diagnostic technology and revisions to data interpretation. Both elementary basics and advanced laboratory techniques are covered in a guide that offers over seventy case studies to help readers understanding the entire laboratory process, making for a top recommendation for veterinary reference collections."  (Midwest Book Reviews, 1 December 2012)

"It's a powerful reference packed with practical applications and should be considered a 'must' for any veterinary reference library."  (Midwest Book Reviews, 1 November 2012)

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Product Details

  • ISBN-13: 9780813810270
  • Publisher: Wiley
  • Publication date: 9/25/2012
  • Edition number: 2
  • Pages: 776
  • Sales rank: 249,966
  • Product dimensions: 8.90 (w) x 10.90 (h) x 1.30 (d)

Meet the Author

Mary Anna Thrall, DVM, MS, DACVP, is a Professor and Section Chief, Department of Pathobiology at Ross University School of Veterinary Medicine in Basseterre, St. Kitts, West Indies.

Glade Weiser, DVM, DACVP, is a Professor, Special Appointment, in the Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine & Biomedical Sciences at Colorado State University in Fort Collins, Colorado.

Robin W. Allison, DVM, PhD, Dipl ACVP, is an Associate Professor in the Department of Veterinary Pathobiology, Center for Veterinary Health Sciences at Oklahoma State University in Stillwater, Oklahoma.

Terry W. Campbell, DVM, PhD is a Professor in the Department of Clinical Sciences at Colorado State University in Fort Collins, Colorado.

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Table of Contents

Contributors ix

Preface x

Preface to the First Edition xii

Section I General Principles of Laboratory Testing and Diagnosis 1

1 Laboratory Technology for Veterinary Medicine 3
Glade Weiser

2 Sample Collection Processing and Analysis of Laboratory Service Options 34
Glade Weiser

3 Perspectives in Laboratory Data Interpretation and Disease Diagnosis 40
Glade Weiser and Robin W. Allison

4 Immunodiagnostics: Current Use and Future Trends in Veterinary Medicine 51
Wayne A. Jensen

Section II Hematology of Common Domestic Species 59

5 Erythrocyte Morphology 61
Mary Anna Thrall

6 Classification of and Diagnostic Approach to Anemia 75
Mary Anna Thrall

7 Nonregenerative Anemia 81
Mary Anna Thrall

8 Regenerative Anemia 87
Mary Anna Thrall

9 Classification of and Diagnostic Approach to Polycythemia 114
Mary Anna Thrall

10 Introduction to Leukocytes and the Leukogram 118
Glade Weiser

11 Neutrophil Production Trafficking and Kinetics 123
Glade Weiser

12 Interpretation of Leukocyte Responses in Disease 127
Glade Weiser

13 Molecular Diagnostics of Hematologic Malignancies 140
Anne Avery

14 Laboratory Evaluation of Bone Marrow 150
Mary Anna Thrall and Glade Weiser

15 Lymphoproliferative Disorders and Myeloid Neoplasms 166
Mary Anna Thrall

16 Diagnosis of Disorders of Hemostasis 185
Dale C. Baker

17 Principles of Blood Transfusion and Crossmatching 205
Diane Brown and Linda M. Vap

Section III Hematology of Common Nondomestic Mammals Birds Reptiles Fish and Amphibians 223

18 Mammalian Hematology: Laboratory Animals and Miscellaneous Species 225
Terry W. Campbell

19 Hematology of Birds 238
Terry W. Campbell

20 Hematology of Reptiles 277
Terry W. Campbell

21 Hematology of Fish 298
Terry W. Campbell

22 Hematology of Amphibians 313
Terry W. Campbell

Section IV Clinical Chemistry of Common Domestic Species 321

23 Laboratory Evaluation and Interpretation of the Urinary System 323
Donald Meuten

24 Laboratory Evaluation of Electrolytes 378
Andrea A. Bohn

25 Laboratory Evaluation of Acid-Base Disorders 393
Glade Weiser

26 Laboratory Evaluation of the Liver 401
Robin W. Allison

27 Laboratory Evaluation of the Pancreas and Glucose Metabolism 425
Robin W. Allison

28 Laboratory Evaluation of Digestion and Intestinal Absorption 441
Dawn Seddon

29 Laboratory Evaluation of Plasma and Serum Proteins 460
Robin W. Allison

30 Laboratory Detection of Muscle Injury 476
Robin W. Allison

31 Laboratory Evaluation of Lipids 480
M. Judith Radin

32 Laboratory Evaluation of the Thyroid Adrenal and Pituitary Glands 497
Donald Meuten

33 Parathyroid Glands and Calcium and Phosphorus Metabolic Pathology 545
Donald Meuten

Section V Clinical Chemistry of Common Nondomestic Mammals Birds Reptiles Fish and Amphibians 569

34 Chemical Chemistry of Mammals: Laboratory Animals and Miscellaneous Species 571
Terry W. Campbell

35 Clinical Chemistry of Birds 582
Terry W. Campbell

36 Clinical Chemistry of Reptiles 599
Terry W. Campbell

37 Clinical Chemistry of Fish and Amphibians 607
Terry W. Campbell

Section VI Clinical Case Presentations 615

This section includes 74 cases with clinicopathologic data accompanied by an interpretive discussion and diagnostic summary.

Index 750

Extra PowerPoint presentations available online at

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