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From The CriticsReviewer: Sue C. Kehl, PhD, D(ABMM)(Medical College of Wisconsin)
Description: This book explores all aspects of viral infection in the animal host. The authors focus on mechanisms that explain complex host-virus interactions.
Purpose: "The book is intended to provide an introduction to viral pathogenesis, assuming the reader has a basic knowledge of the fundamentals of virology. The book focuses on basic principles of pathogenesis and immunity; it does not include a virus by virus listing of mechanisms. The book fills a major gap between basic virus structure and replication texts and the complex, all encompassing, virus by virus texts. "
Audience: The book is intended for students with a basic knowledge of virology who desire an introduction to the topic of viral pathogenesis. In addition to medical students, this book is also appropriate for undergraduate and graduate students studying virology. Residents and physicians may also find that this not-too-complex book will provide a good understanding of viral pathogenesis. The author, a recognized expert in the field of virology, partners with an expert in the specific field discussed in each chapter.
Features: The first section introduces the reader to the first events of viral infection and virus-cell interactions. The second section focuses on the host response. Section three is concerned with viral persistence and oncogenesis. Section four focuses on prevention of infection through vaccination. Each chapter includes references for review as well as references for further study. In many chapters, the classic papers for that subject are cited. The book includes many tables, charts and drawings. The drawings provide an excellent depiction of the mechanisms being discussed. The book does not include a discussion of antiviral agents. The development of resistant viruses is discussed only as it relates to HIV.
Assessment: "The book fills a major gap in virology texts. Many introductory virology books do not delve into the basic principles of pathogenesis while other complex texts assume this knowledge. It is an excellent addition to the library of students of virology. "