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More About This Textbook
Overview
Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic.
• Offers almost a 20% expansion over the first edition
• Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic
• Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology
• Now in four color throughout!
Editorial Reviews
From The Critics
Reviewer: Sue C. Kehl, PhD, D(ABMM)(Medical College of Wisconsin)Description: This book explores all aspects of viral infection in the animal host. The authors focus on mechanisms that explain complex host-virus interactions.
Purpose: "The book is intended to provide an introduction to viral pathogenesis, assuming the reader has a basic knowledge of the fundamentals of virology. The book focuses on basic principles of pathogenesis and immunity; it does not include a virus by virus listing of mechanisms. The book fills a major gap between basic virus structure and replication texts and the complex, all encompassing, virus by virus texts. "
Audience: The book is intended for students with a basic knowledge of virology who desire an introduction to the topic of viral pathogenesis. In addition to medical students, this book is also appropriate for undergraduate and graduate students studying virology. Residents and physicians may also find that this not-too-complex book will provide a good understanding of viral pathogenesis. The author, a recognized expert in the field of virology, partners with an expert in the specific field discussed in each chapter.
Features: The first section introduces the reader to the first events of viral infection and virus-cell interactions. The second section focuses on the host response. Section three is concerned with viral persistence and oncogenesis. Section four focuses on prevention of infection through vaccination. Each chapter includes references for review as well as references for further study. In many chapters, the classic papers for that subject are cited. The book includes many tables, charts and drawings. The drawings provide an excellent depiction of the mechanisms being discussed. The book does not include a discussion of antiviral agents. The development of resistant viruses is discussed only as it relates to HIV.
Assessment: "The book fills a major gap in virology texts. Many introductory virology books do not delve into the basic principles of pathogenesis while other complex texts assume this knowledge. It is an excellent addition to the library of students of virology. "
3 Stars from Doody
Product Details
Related Subjects
Table of Contents
ESSENTIALS OF PATHOGENESIS
Historical roots
The sequential steps in viral infection
Cellular receptors and viral tropism
Virus-cell interactions
HOST RESPONSE TO VIRAL INFECTION
Innate immunity
Immune responses to viral infection
Virus-induced immunopathology
Virus-induced immunosuppression
VIRUS-HOST INTERACTIONS
Viral virulence
Viral persistence
Viral oncogenesis: retroviruses
Viral oncogenesis: DNA viruses
Host susceptibility to viral diseases
HIV, SIV, and the pathogenesis of AIDS
ECOLOGY AND CONTROL OF VIRAL INFECTIONS
Emerging viral diseases
Antiviral therapy
Viral vaccines