Viruses and Bone Marrow: Basic Research and Clinical Practice

Overview

This reference offers detailed descriptions of the interaction of viruses with human and animal haematopoietic cells, examines the role of viruses in human disease and important animal models, and elucidates the relationship of the immune reponse both in restricting infections and mediating organ damage.;Supplying rigorous, focussed discussions which should be of benefit to both clinicians and basic scientists, Viruses and Bone Marrow: gives a general overview of viral infection in haematopoietic cells, including...

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Overview

This reference offers detailed descriptions of the interaction of viruses with human and animal haematopoietic cells, examines the role of viruses in human disease and important animal models, and elucidates the relationship of the immune reponse both in restricting infections and mediating organ damage.;Supplying rigorous, focussed discussions which should be of benefit to both clinicians and basic scientists, Viruses and Bone Marrow: gives a general overview of viral infection in haematopoietic cells, including immune response and pathological mechanisms; describes human parvovirus and feline panleukopenia virus; presents the latest information on Epstein-Barr virus and cytomegalovirus; indicates the role of hepatitis viruses and flaviviruses in cytopenias; highlights HIV, Friend leukaemia virus, and feline leukaemia virus; reviews the use of viruses as molecular tools in gene therapy; and more.;With over 1300 literature citations, tables, figures, and micrographs, Viruses and Bone Marrow is intended as a resource for haematologists, oncologists, microbiologists, virologists, infectious disease specialists, cell biologists, and graduate and medical school students in these disciplines.

This book contains black-and-white illustrations.

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Editorial Reviews

Booknews
This volume provides an exposition of the state of the art of viruses and viral infections affecting the bone marrow. The coverage is broad, ranging from the discovery of the specific viruses and first recognition of their clinical manifestations to the characteristics of the viruses and cloning of their genes, with emphasis on pathogenetic mechanisms and therapeutic approaches. The volume is organized in six parts: general aspects of virus infection of hematopoietic cells, parvoviruses, herpesviruses, flaviviruses, retroviruses, and viruses as vectors for gene therapy. For infectious disease specialists who care for patients with viral infections, hematologists who treat blood diseases of viral origin, and basic scientists, especially virologists and immunologists. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780824788339
  • Publisher: Taylor & Francis
  • Publication date: 1/1/1993
  • Series: Hematology Series , #16
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 416
  • Product dimensions: 6.25 (w) x 9.25 (h) x 1.25 (d)

Table of Contents

Part 1 General aspects of virus infection of haematopoietic cells: mechanisms of viral pathogenesis, Raymond M. Welsh and Hugh I. McFarland; immune response to viral infection, Caroline I.B. Kurtz and Robert S. Fujinami. Part 2 Parvoviruses: B19 parvoviruses, Neal S. Young; feline panleukopenia virus, Gary Kurtzman. Part 3 Herpesviruses: Epstein-Barr virus, Bruce G. Baranski and Ian T. Magrath; human cytomegalovirus, Stephen St Jeor and Jaroslaw P. Maciejewski. Part 4 Flaviviruses: Dengue virus and haematopoiesis, Stephen J. Rosenfeld et al; hepatitis viruses and bone marrow depression, Pascal Bouffard and Jerome B. Zeldis. Part 5 Retroviruses: human immunodeficiency virus and the bone marrow, Jerry L. Spivak and Barbara Potts; friend spleen focus-forming virus, Sandra K. Ruscetti; feline leukaemia virus, Janis L. Abkowitz and Michael L. Linenberger. Part 6 Viruses as vectors for gene therapy: viruses as molecular tools, Arthur W. Nienhuis et al.

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