Voltammetric Methods in Brain Systems / Edition 1

by Alan A. Boulton, Glen B. Baker, Ralph Adams

Overview

Voltammetric Methods in Brain Systems offers neuroscientists at all levels of expertise a combination of theory and practical how-to instructions for using in vivo and on-line neurotransmitter measurements in their experimental brain systems. Coverage includes the entire spectrum of applications for in situ, brain slices, transplant media, cell cultures, and single cells. Emphasis is on fast measurements that reveal release-reuptake information on transmitter systems. How-to information ranges from ample detail on the preparation of electrodes, to practical experimental details, to the interpretation of results.

Written by many of the world's leading experts-often those whose laboratories have spearheaded work in the area-Voltammetric Methods in Brain Systems provides insightful views on all the best approaches and experimental techniques, with sufficient introductory material and practical detail to satisfy both newcomers and experienced researchers.

Product Details

ISBN-13:	9781617370090
Publisher:	Springer-Verlag New York, LLC
Publication date:	11/09/2010
Series:	Neuromethods , #27
Edition description:	Softcover reprint of hardcover 1st ed. 1995
Pages:	349
Product dimensions:	5.98(w) x 9.02(h) x 0.35(d)

About the Author

Boulton, Alan A (Univ of Saskatchewan); Baker, Glen B (Univ of Alberta); Adams, Ralph N (Univ of Kansas)

The contributors represent the specialties of chemistry, neurosurgery, and anesthesiology. Most are from academic medical centers in the U.S., the U.K., Ireland, and France. Institutions prominently represented include Pennsylvania State, London Hospital, and New York Univ.

Table of Contents

Carbon Electrode Surface Chemistry.- Diffusion and Ion Shifts in the Brain Extracellular Microenvironment and Their Relevance for Voltammetric Measurements.- Fast Cyclic Voltammetry in Brain Slices.- Rapid Chronocoulometric Measurements of Norepinephrine Overflow and Clearance in CNS Tissues.- Monitoring Dopamine and Noradrenaline Release in Central and Peripheral Nervous Systems with Treated and Untreated Carbon-Fiber Electrodes.- Regional Differences in Dopamine Release, Uptake, and Diffusion Measured by Fast-Scan Cyclic Voltammetry.- The Measurement of Brain Ascorbate In Vivo and Its Link with Excitatory Amino Acid Neurotransmission.- Voltammetric and Amperometric Probes for Single-Cell Analysis.- Measurement of the Time-Resolved Kinetics of Biogenic Amine Release and Transporter Activity by Rotating Disk Electrode Voltammetry In Vitro.

Editorial Reviews

This book is a very useful guide to the different voltammetry "engines" currently in use...all research groups involved in vivo voltammetry would be well advised to have a copy of this book. It is an invaluble source for...the different techniques and research workers in the field.-Quarterly Review of Biology

From the Publisher

Offers neuroscientists at all levels of expertise a combination of theory and practical instructions for using in vivo and on-line neurotransmitter measurements in their experimental brain systems. Coverage includes the entire spectrum of applications for in situ, brain slices, transplant media, cell cultures, and single cells. Emphasis is on fast measurements that reveal release-reuptake information on transmitter systems. Practical information ranges from the preparation of electrodes, to experimental details, to the interpretation of results. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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