Wall and Melzack's Textbook of Pain e-dition: Text with Continually Updated Online Reference / Edition 5

Hardcover (Print)
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Now available as a multimedia e-dition, the new 5th Edition of Wall and Melzack's Textbook of Pain, revised under new editorial leadership, and with a host of new, multidisciplinary international contributors covers virtually every aspect of pain. Read all the latest about the neurophysiology, psychology, and assessment of every type of pain syndrome. Describes today's full range of pharmacologic, surgical, electrostimulative, physiotherapeutic, and psychological management options. The e-dition offers the book plus a website. All drug information is linked to Mosby's Drug Consult, all references are linked to PubMed, and all illustrations and tables can be downloaded into PowerPoint slides for presentations.

• Covers all aspects of the physiology, psychology, assessment, and management of pain.
• Features contributions from a "who's who" of authorities in pain medicine, ensuring that the book is the most current, reliable, and complete core reference in the field.

• Features the expertise of two highly respected new editors—Stephen McMahon, PhD and Martin Koltzenburg, MD, PhD—as well as many new contributors, for a completely fresh look at the subject.
• Uses a new, consistent format to present therapeutic options in an easy-to-review manner.
• Provides increased coverage of anesthetic techniques.
• Incorporates the most recent pharmacologic developments involving drug categories such as anticonvulsants, antidepressants, muscle relaxants, and cannabinoids.
• Several new chapters, including the one on addiction to pain medication, clinical trials, and evidence-based medicine in pain, extended headache section (1 chapter in 4/e vs. 4 chapters in 5/e).
• Offers many new illustrations to provide a colorful and graphic representation of important concepts.
• Reflects all of the changes that have taken place in this rapidly moving field.

Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

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Editorial Reviews

Doody's Review Service
Reviewer: Tariq M. Malik, MD (University of Chicago Pritzker School of Medicine)
Description: This is a complete textbook of pain that keeps its focus and wastes no time discussing issues that have no clinical utility like billing or establishing a pain clinic. The last edition was published in 1999 and this edition was certainly needed in view of the changes that have occurred in the field.
Purpose: The main theme of this book has always been the synthesis of basic and clinical science because of the personal experience of the original editors in bench and bedside research, and the current editors have continued that tradition. Chronic pain is still not fully understood and hence it is poorly controlled. Only when pain is better understood at molecular level are new and improved therapies discovered. This book continues to be the source of that missing link between the basic and clinical aspects of pain that is readily available to pain physicians.
Audience: This is best suited for practitioners who deal with pain in any form: acute or chronic, somatic or visceral. In that respect, it is useful for every practitioner, including neurologists, pain physicians, urologists, gastroenterologists or even gynecologists, etc. It is intended to improve the understanding of pain. The contributing authors are well known authorities in their fields.
Features: The book covers the topic of pain in a very logical way. It starts with pain physiology and anatomy in the peripheral and central nervous system. Then it goes on to discuss different pharmacological methods to target different pain conditions based on abnormal physiology. This is followed by discussions of different clinical conditions of pain, namely headache or cancer pain, and their management. The most outstanding features of the book, other than its content, are the color illustrations and the print, which are very pleasing to the eye. Most pain books I am familiar with are very dull, particularly in the discussion of the basic science. The best part of this edition is the online version which is continually updated, so one can always rely on this source. One drawback is the limited material on interventional pain techniques. Interventional pain physicians may find this book less than complete. Another shortcoming is the limited amount of time the book spends on chronic back pain, which consumes 80 percent of the clinical practice of an interventional pain physician.
Assessment: This book does a lot to improve the understanding of pain, but it is not meant to teach procedures in pain management. There are quite a few books available on pain management, including Bonica's Management of Pain, 3rd edition, Loeser et al. (Lippincott Williams & Wilkins, 2001), Practical Management of Pain, 3rd edition, Raj et al. (Mosby, 2000), and Principles and Practice of Pain Medicine, 2nd edition (McGraw-Hill, 2004), by Warfield and Bajwa. These all serve different purposes, whether as a quick read for an exam or just to learn procedures. No book works more at improving the understanding of pain than this one. The book has one theme — applying basic knowledge to clinical situations. It is not based on personal experience or case reports, everything is a scientific fact. The previous edition was six years old and certainly needed to be updated. No less important is the decision to have an online version so that the book never loses its up-to-date quality.
From the Publisher
"It goes without saying that Wall and Melzack's work is the preemptive text on pain...Required reading for all pain specialists."
Journal of Neurosurgical Anesthesia

"An indispensable resource...A masterpiece."

"The most comprehensive of any of the books dealing with pain."

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780443067914
  • Publisher: Elsevier Health Sciences
  • Publication date: 9/21/2005
  • Edition description: REV
  • Edition number: 5
  • Pages: 1280
  • Product dimensions: 9.30 (w) x 11.50 (h) x 2.70 (d)

Table of Contents

Section 1. Neurobiology of pain

1. Peripheral mechanisms of cutaneous nociception

2. Cellular and molecular properties of primary afferent neurons

3. Inflammatory mediators and modulators of pain

4. Neuroanatomical substrates of spinal nociception

5. Plasticity and pain: role of the dorsal horn

6. Representation of pain in the brain

7. Central nervous system mechanisms of pain modulation

8. Development of pain pathways and mechanisms

9. The genetics of pain

10. Animal models of pain

11. Ascending projection systems

12. Autonomic-endocrine-immune interactions in acute and chronic pain

13. Itch

Section 2. Assessment and psychology of pain

14. Emotions and psychobiology

15. Cognitive and learning aspects

16. Psychiatric disorders and pain

17. Studies of pain in human subjects

18. Pain assessment in adult patients

19. Measurement and assessment of paediatric pain

20. Assessment of pain beliefs, coping, and function

21. Hypnotic analgesia

22. The cognitive-behavioural approach to pain management

23. Pain, opiates and addiction

24. Placebo analgesia

Section 3. Pharmacology and Treatment of Pain

25. Central pharmacology of nociceptive transmission

26. Methods of therapeutic trials

27. Opiates: basic mechanisms

28. Opioids: clinical use

29. Antipyretic analgesics: basic aspects

30. NSAIDs and Coxibs: clinical use

31. Antidepressant analgesics: a systematic review and comparative study

32. Anticonvulsant medications in neuropathic pain

33. Local anaesthetic blocks and epidurals

34. Cannabinoids

35. Analgesic drugs in development

36. Supratentorial neurosurgery for the treatment of pain

37. Spinal cord and brain stimulation

38. Transcutaneous electrical nerve stimulation and acupuncture

39. Peripheral and central nervous system surgery for pain

40. Physiotherapy and pain

Section 4. Clinical states: Deep somatic tissue

41. Basic mechanisms of deep somatic pain

42. Postoperative pain and its management

43. Osteoarthritis and rheumatoid arthritis

44. Myofascial pain and fibromyalgia syndrome

45. Surgical treatment for back and neck pain

46. Low back pain

47. Repetitive strain injury

Section 5. Viscera

48. Visceral pain: basic mechanisms

49. Thorax

50. A clinical perspective on abdominal pain

51. Genitourinary pain

52. Obstetric pain

Section 6. Clinical States: Headache and facial pain

53. Acute and chronic dental and orofacial pain

54. Headache

55. Primary neurovasuclar headache

56. Tension-type headache

57. Pain in and around the eye

Section 7. Clinical states: Neuropathic pain

58. Response of nerves to injury in relation to neuropathic pain

59. Mechanisms of experimental neuropathic pain: integration from animal models

60. Central consequences of peripheral nerve damage

61. Phantom limb

62. Painful peripheral neuropathies

63. Trigeminal and glossopharyngeal neuralgia

64. Complex regional pain syndromes

65. Root disorders and arachnoiditis

66. Pain following spinal cord injury

67. Central pain

68. Pharmacological therapy for neuropathic pain

Section 8. Clinical states: Cancer pain

69. Cancer pain: causes, consequences and therapeutic opportunities

70. The assessment of cancer pain

71. Analgesic therapy and palliative care in children

72. Cancer pain: treatment overview

73. Pain control in the care of the dying

Section 9. Clinical States: Special cases

74. Pain in the elderly

75. Sex and gender differences in pain and its relief

76. Epidemiology of pain


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