Williams Manual of Hematology, Eighth Edition / Edition 8

Williams Manual of Hematology, Eighth Edition / Edition 8

by Marshall Lichtman

ISBN-10: 007162242X

ISBN-13: 9780071622424

Pub. Date: 05/10/2011

Publisher: McGraw-Hill Professional Publishing

A convenient full-color reference distilled from the world’s leading hematology text – perfect when you need answers in the office, clinic, or on hospital rounds.

Williams Manual of Hematology, 8e is a concise and easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein

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A convenient full-color reference distilled from the world’s leading hematology text – perfect when you need answers in the office, clinic, or on hospital rounds.

Williams Manual of Hematology, 8e is a concise and easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, 8e, this handy, easily transported reference has been carefully edited to deliver only the most clinical point-of-care facts.

Covering both common and uncommon blood disorders, this complete guide includes sections on:

  • Disorders of red cells
  • Disorders of granulocytes
  • Disorders of monocytes and macrophages
  • The clonal myeloid disorders
  • The polyclonal lymphoid diseases
  • The clonal lymphoid and plasma cell diseases
  • Disorders of platelets and hemostasis
  • Disorders of coagulation proteins
  • Transfusion and hemapheresis

Now in full color for the first time, Williams Manual of Hematology, 8e is the fastest and most convenient way to access the unmatched clinical authority of Williams Hematology, 8e.

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Product Details

McGraw-Hill Professional Publishing
Publication date:
Edition description:
New Edition
Product dimensions:
4.80(w) x 8.30(h) x 1.10(d)

Related Subjects

Table of Contents

Ch. 1Initial approach to the patient : history and physical examination3
Ch. 2Examination of the blood11
Ch. 3Examination of the marrow21
Ch. 4Structure of the marrow and the hematopoietic microenvironment35
Ch. 5The lymphoid tissues73
Ch. 6Hematology of the newborn81
Ch. 7Hematology during pregnancy101
Ch. 8Hematology in older persons111
Ch. 9Genetic principles and molecular biology125
Ch. 10Cytogenetics and gene rearrangement137
Ch. 11Apoptosis151
Ch. 12Cell cycle regulation and hematological disorders159
Ch. 13Signal transduction pathways173
Ch. 14The cluster of differentiation (CD) antigens183
Ch. 15Hematopoietic stem cells, progenitors, and cytokines201
Ch. 16The inflammatory response221
Ch. 17Innate immunity231
Ch. 18Dendritic cells and the control of innate and adaptive immunity239
Ch. 19Pharmacology and toxicity of antineoplastic drugs249
Ch. 20Treatment of infections in the immunocompromised host275
Ch. 21Principles of antithrombotic therapy283
Ch. 22Principles of hematopoietic cell transplantation301
Ch. 23Principles of immune cell therapy323
Ch. 24Principles of vaccine therapy333
Ch. 25Principles of therapeutic apheresis : indications, efficacy, complications337
Ch. 26Principles of gene transfer for therapy345
Ch. 27Pain management355
Ch. 28Morphology of the erythron369
Ch. 29Composition of the erythrocyte387
Ch. 30Production of erythrocytes393
Ch. 31Destruction of erythrocytes405
Ch. 32Clinical manifestations and classification of erythrocyte disorders411
Ch. 33Aplastic anemia419
Ch. 34Pure red cell aplasia437
Ch. 35Anemia of chronic renal failure449
Ch. 36Anemia of endocrine disorders459
Ch. 37The congenital dyserythropoietic anemias463
Ch. 38Paroxysmal nocturnal hemoglobinuria469
Ch. 39Folate, cobalamin, and megaloblastic anemias477
Ch. 40Disorders of iron metabolism511
Ch. 41Anemia resulting from other nutritional deficiencies555
Ch. 42Anemia associated with marrow infiltration561
Ch. 43Anemia of chronic disease565
Ch. 44Disorders of the red blood cell membrane : hereditary spherocytosis, elliptocytosis, and related disorders571
Ch. 45Disorders of red cells resulting from enzyme abnormalities603
Ch. 46Disorders of globin synthesis : the thalassemias633
Ch. 47Disorders of hemoglobin structure : sickle cell anemia and related abnormalities667
Ch. 48Methemoglobinemia and other causes of cyanosis701
Ch. 49Hemolytic anemia resulting from physical injury to red cells709
Ch. 50Hemolytic anemia resulting from chemical and physical agents717
Ch. 51Hemolytic anemia resulting from infections with microorganisms723
Ch. 52Hemolytic anemia resulting from immune injury729
Ch. 53Alloimmune hemolytic disease of the newborn751
Ch. 54Acute blood loss anemia767
Ch. 55Hypersplenism and hyposplenism773
Ch. 56Primary and secondary polycythemias (erythrocytosis)779
Ch. 57The hematologic aspects of porphyria803
Ch. 58Hereditary and acquired sideroblastic anemias823
Ch. 59Morphology of neutrophils, eosinophils, and basophils831
Ch. 60Composition of neutrophils847
Ch. 61Production, distribution, and fate of neutrophils855
Ch. 62Eosinophils and their disorders863
Ch. 63Basophils and mast cells and their disorders879
Ch. 64Classification and clinical manifestations of neutrophil disorders899
Ch. 65Neutropenia and neutrophilia907
Ch. 66Disorders of neutrophil function921
Ch. 67Morphology of monocytes and macrophages961
Ch. 68Biochemistry and function of monocytes and macrophages971
Ch. 69Production, distribution, and fate of monocytes and macrophages979
Ch. 70Classification and clinical manifestations of disorders of monocytes and macrophages983
Ch. 71Monocytosis and monocytopenia987
Ch. 72Inflammatory and malignant histiocytosis993
Ch. 73Lipid storage diseases1009
Ch. 74Morphology of lymphocytes and plasma cells1023
Ch. 75Composition and biochemistry of lymphocytes and plasma cells1031
Ch. 76Lymphopoiesis1039
Ch. 77Functions of B lymphocytes and plasma cells in immunoglobulin production1051
Ch. 78Functions of T lymphocytes : T cell receptors for antigen1065
Ch. 79Functions of natural killer cells1077
Ch. 80Classification and clinical manifestations of lymphocyte and plasma cell disorders1083
Ch. 81Lymphocytosis and lymphocytopenia1087
Ch. 82Immunodeficiency diseases1099
Ch. 83Hematological aspects of human immunodeficiency syndrome1109
Ch. 84Mononucleosis syndromes1135
Ch. 85Classification and clinical manifestations of the clonal myeloid disorders1147
Ch. 86Myelodysplastic syndromes (clonal cytopenias and oligoblastic leukemia)1157
Ch. 87Acute myelogenous leukemia1183
Ch. 88Chronic myelogenous leukemia and related disorders1237
Ch. 89Idiopathic myelofibrosis (myelofibrosis with myeloid metaplasia)1295
Ch. 90Classification of malignant lymphoid disorders1315
Ch. 91Acute lymphoblastic leukemia1321
Ch. 92Chronic lymphocytic leukemia and related diseases1343
Ch. 93Hairy cell leukemia1385
Ch. 94Large granular lymphocytic leukemia1395
Ch. 95Pathology of lymphomas1399
Ch. 96The non-Hodgkin lymphomas1407
Ch. 97Hodgkin lymphoma1461
Ch. 98Plasma cell neoplasms : general considerations1483
Ch. 99Essential monoclonal gammopathies1491
Ch. 100Plasma cell myeloma1501
Ch. 101The amyloidoses1535
Ch. 102Macroglobulinemia1549
Ch. 103Heavy chain diseases1561
Ch. 104Megakaryopoiesis and thrombopoiesis1571
Ch. 105Platelet morphology, biochemistry, and function1587
Ch. 106Molecular biology and biochemistry of the coagulation factors and pathways of hemostasis1665
Ch. 107Control of coagulation reactions1695
Ch. 108Vascular function in hemostasis1715
Ch. 109Classification, clinical manifestations, and evaluation of disorders of hemostasis1741
Ch. 110Thrombocytopenia1749
Ch. 111Essential thrombocythemia and thrombocytosis1785
Ch. 112Hereditary qualitative platelet disorders1795
Ch. 113Acquired qualitative platelet disorders1833
Ch. 114The vascular purpuras1857
Ch. 115Hemophilia A and hemophilia B1867
Ch. 116Inherited deficiencies of coagulation factors II, V, VII, X, XI, and XIII and combined deficiencies of factors V and VIII and of the vitamin K-dependent factors1887
Ch. 117Hereditary fibrinogen abnormalities1909
Ch. 118Von Willebrand disease1929
Ch. 119Antibody-mediated coagulation factor deficiencies1947
Ch. 120Hemostatic dysfunction related to liver diseases and liver transplantation1953
Ch. 121Disseminated intravascular coagulation1959
Ch. 122Hereditary thrombophilia1981
Ch. 123The antiphospholipid syndrome2009
Ch. 124Antibody-mediated thrombotic disorders : idiopathic thrombotic thrombocytopenic purpura and heparin-induced thrombocytopenia2031
Ch. 125Venous thrombosis2055
Ch. 126Atherothrombosis : disease initiation, progression, and treatment2067
Ch. 127Fibrinolysis and thrombolysis2089
Ch. 128Erythrocyte antigens and antibodies2119
Ch. 129Human leukocyte and platelet antigens2137
Ch. 130Blood procurement and screening2151
Ch. 131Preservation and clinical use of erythrocytes and whole blood2159
Ch. 132Preservation and clinical use of platelets2175

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