Williams Textbook of Endocrinology / Edition 10

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Philadelphia, PA 2002 Hard cover 10th ed. New. BRAND NEW(NEVER OPENED)! ! /minor bumping on cover edge-No international, No expedite shipping avilable[GL5] Sewn binding. Cloth ... over boards. 1968 p. Contains: Illustrations. Williams Textbook of Endocrinology. Audience: General/trade. Read more Show Less

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Overview

The state-of-the-art, tenth edition of endocrinology's classic text bridges the gap between basic science and endocrinology clinical practice. Thoroughly revised and updated, it includes new material on the thyroid and diabetes mellitus to reflect today's explosive increase in knowledge. Written by an outstanding team of authors, the 10th edition features numerous new authors who provide fresh perspectives.

• Presents a wealth of clinical information in a manageable size and format
• Contributors are at the forefronts of their disciplines
• Serves as a bridge between basic science and clinical endocrinology

• Diabetes mellitus and it complications has been greatly expanded and now includes 3 separate chapters.
• 4 new chapters
• Two new editors provide a fresh perspective on the material
• Figures have been added to the Diabetes Mellitus chapters
• Much of the art has been revised and includes new algorithms in many chapters
• Access to abstracts is available through Medline

With 71 expert contributors

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Jennifer M. Cunningham, MD (University of Chicago Medical Center)
Description: This updated edition of a general endocrine textbook presents normal endocrine function at both the molecular and clinical levels, as well as states of endocrine pathology. It is a significant update from the prior version published in 1998.
Purpose: The purpose is to update the previous edition using a fresh approach to the presentation of the essentials of clinical endocrinology. The stated goal is to incorporate molecular and physiological science into scholarly yet practical presentations on disease management. New authors were invited to prepare many of the chapters, so this work is more than just adding new information to previously written chapters. Overall, the book is successful in achieving its goals, although there certainly is variability from chapter to chapter in the practical use of the extensive knowledge.
Audience: The authors do not specify an audience, but clearly it is appropriate for a wide range of readers, from students to practitioners of endocrinology. For students, it would be particularly beneficial in its presentation of basic endocrine physiology, as well as a reference for different disease states. For endocrine practitioners, it is useful for the details it gives regarding many of the disease states as well as the controversies and pitfalls in testing for these. For non-endocrine practitioners, however, the details may obscure the basics of the endocrine evaluations for specific disease states and they may find this book less user-friendly.
Features: Most chapters begin with an explanation of the physiology and/or pathophysiology of the endocrine organ and its disease states. The authors then discuss the clinical characteristics, including treatment and diagnosis, of endocrine disease states. The scope of topics is excellent, including chapters on such subjects as endocrinology and aging and endocrine responsive cancer as opposed to organization simply by individual endocrine organs. The book differs from others in the length of its chapters, which are broken down into smaller sections and subsections. The purpose seems to be to locate all items related to a given subject within the same chapter. However, this can make it somewhat cumbersome to use, and readers in search of a particular topic will find the index far more helpful than the table of contents, which lists only the major chapter headings. The figures and illustrations are of good quality and are given adequate emphasis. Inexplicably, there is a large section of color photographs and figures after chapter 12. These are of good quality but unlikely to be appreciated by most readers due to their seemingly random location in the book. They should be placed, with appropriate notation in the table of contents, at the back or front of the book. Despite the book's stated goals, there is a lot of variability among chapters regarding clinical utility. The thyroid neoplasia section of Chapter 13 seems to focus on guiding a practitioner in patient management, with subsections labeled follow-up strategy. The section on menopause, on the other hand, fails to comment on any of the very relevant nonhormonal treatments available for menopausal symptoms.
Assessment: Overall, this is a quality book and provides a good update in the major areas of endocrinology. Its presentation of the science of endocrinology is excellent. The clinical application of this science is excellent in some chapters but difficult to distinguish in others. It is certainly a worthwhile contribution to the field, but those in search of practical direction regarding disease management may need to consult other books as well, depending on the subject matter.
Monica C. Skarulis
This ninth edition text is a concise, definitive clinical resource that provides a comprehensive overview of the entire discipline. Two new editors joined the team to reorganize contents, add new chapters, and reassign nine existing chapters to new contributors. The result is an extensively revised text from the previous edition published in 1992. The goal of the current editors echoes the commitment of their predecessors since the first edition, published in 1950: to provide a condensed authoritative reference bridging the rapidly advancing knowledge acquired in basic science with clinical endocrinology. Today, the challenge looms larger and the goal is-more elusive, particularly in achieving a condensed product that is meaningful. Clinicians and students will find this 1819-page, single volume text convenient to use for a quick overview of topics, which are extensively referenced and illustrated with many instructive figures. The editors have created a ""supersaturated"" text with calculated concessions in both basic science and clinical arenas. The ratio of basic science to clinical endocrinology varies throughout the chapters of the text. For example, the chapter on adrenal cortex covers diagnostic testing and treatment of disorders. In contrast, diabetes mellitus is divided evenly between molecular and clinical topics in a very brief and informative chapter on an enormous topic. The first section boasts updated topics in molecular endocrinology, genetics, and cell biology written by authorities in these fields. Two new chapters include discussion of the pathogenesis of endocrine neoplasm and the fundamentals of autoimmunity for endocrinologists. The strength of thistextbook (comprehensive and condensed) arguably leads to its limitation. While most clinical pertinent topics are covered, they are dealt with tersely. Despite this, this is an important textbook that should be required reading for all students of endocrinology.

5 Stars! from Doody
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Product Details

  • ISBN-13: 9780721691848
  • Publisher: Elsevier Health Sciences
  • Publication date: 12/12/2002
  • Edition description: REV
  • Edition number: 10
  • Pages: 1968
  • Product dimensions: 8.97 (w) x 11.18 (h) x 2.61 (d)

Table of Contents

SECTION I: HORMONES AND HORMONE ACTION

1. Principles of Endocrinology (Henry M. Kronenberg, Shlomo Melmed, P. Reed Larsen, and Kenneth S. Polonsky)
2. The Endocrine Patient (Daniel D. Federman)
3. Genetic Control of Peptide Hormone Formation (Joel F. Habener)
4. Mechanism of Action of Hormones that Act as Nuclear Hormone Receptors (Mitchell A. Lazar)
5. Mechanism of Action of Hormones that Act at the Cell Surface (Allen Spiegel, Christin Carter-Su, and Simeon I. Taylor)
6. Laboratory Techniques for Recognition of Endocrine Disorders (George G. Klee)

SECTION II: HYPOTHALAMUS AND PITUITARY

7. Neuroendocrinology (Roger D. Cone, Malcolm J. Low, Joel K. Elmquist, and Judy L. Cameron)
8. The Anterior Pituitary (Shlomo Melmed and David L. Kleinberg)
9. The Posterior Pituitary (Alan G. Robinson and Joseph G. Verbalis)

SECTION III: THYROID

10. THYROID physiology and Diagnostic Evaluation of Patients with Thyroid Disorders (P. Reed Larsen, Terry F. Davies, Martin-Jean Schlumberger, and Ian D. Hay)
11. Thyrotoxicosis (Terry F. Davies and P. Reed Larsen)
12. Hypothyroidism and Thyroiditis (P. Reed Larsen and Terry F. Davies)
13. Nontoxic Goiter and Thyroid Neoplasia (Martin-Jean Schlumberger, Sebastiano Filetti, and Ian D. Hay)

SECTION IV: ADRENAL

14. The Adrenal Cortex (Paul M. Stewart)
15. Endocrine Hypertension (Robert G. Dluhy, Jennifer E. Lawrence, and Gordon H. Williams)

SECTION V: REPRODUCTION

16. The Physiology and Pathology of the Female Reproductive Axis (Serdar E. Bulun and Eli Y. Adashi)
17. Fertility Control: Current Approaches and Global Aspects (Michael Kafrissen and Eli Y. Adashi)
18. Disorders of the Testes and the Male Reproductive Tract (James E. Griffin and Jean D. Wilson)
19. Sexual Dysfunction in Men and Women (Shalender Bhasin, Jennifer Berman, Laura Berman, and Wayne J.G. Hellstrom)

SECTION VI: ENDOCRINOLOGY AND THE LIFE SPAN

20. Endocrine Changes of Pregnancy (Glenn D. Braunstein)
21. Endocrinology of Fetal Development (Delbert A. Fisher)
22. Disorders of Sex Differentiation (Melvin M. Grumbach, Felix A. Conte, and Ieuan A. Hughes)
23. Normal and Aberrant Growth (Edward O. Reiter and Ron G. Rosenfeld)
24. Puberty: Ontogeny, Neuroendocrinology, Physiology, and Disorders (Melvin M. Grumbach and Dennis M. Styne)
25. Endocrinology and Aging (Steven W.J. Lamberts

SECTION VII: MINERAL METABOLISM

26. Hormones and Disorders of Mineral Metabolism (F. Richard Bringhurst, Marie B. Demay, and Henry M. Kronenberg)
27. Metabolic Bone Disease (Lawrence G. Raisz, Barbara E. Kream, and Joseph A. Lorenzo)
28. Kidney Stones (Rebeca D. Monk and David A. Bushinsky)

SECTION VIII: DISORDERS OF CAROHYDRATE AND LIPID METABOLISM

29. Type 2 Diabetes Mellitus (John B. Buse, Kenneth S. Polonsky, and Charles F. Burant)
30. Type 1 Diabetes Mellitus (George S. Eisenbarth, Kenneth S. Polonsky, and John B. Buse)
31. Complications of Diabetes Mellitus (Michael Brownlee, Lloyd P. Aiello, Eli Friedman, Aaron I. Vinik, Richard W. Nesto, and Andrew J.M. Boulton)
32. Glucose Homeostasis and Hypoglycemia (Philip E. Cryer)
33. Obesity (Samuel Klein and Johannes A. Romijn)
34. Disorders of Lipid Metabolism (Robert W. Mahley, Karl H. Weisgraber, and Robert V. Farese, Jr.)

SECTION IX: POLYENDOCRINE DISORDERS

35. Pathogenesis of Endocrine Tumors (Andrew Arnold)
36. Multiple Endocrine Neoplasias (Robert F. Gagel and Stephen J. Marx)
37. The Immunoendocrinopathy Syndromes (George S. Eisenbarth and Peter A. Gottlieb)

SECTION X: PARAENDOCRINE AND NEOPLASTIC SYNDROMES

38. Gastrointestinal Hormones and Gut Endocrine Tumors (Robin P. Boushey and Daniel J. Drucker)
39. Endocrine – Responsive Cancer (Richard Santen)
40. Humoral Manifestations of Malignancy (Gordon J. Strewler)
41. Carcinoid Tumors, Carcinoid Syndrome, and Related Disorders (Kjell E. Öberg)

INDEX

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Preface

Williams Textbook of Endocrinology is designed to serve as a bridge between basic science and clinical endocrinology. The main objective is to provide a condensed and authoritative discussion of the management of clinical endocrinopathies, based upon the application of fundamental information obtained from chemical and physiologic investigations.

The ninth edition of Williams Textbook of Endocrinology has been extensively revised to reflect the rapid change in endocrine science. Molecular genetics, cell biology, and molecular biology are integrated throughout. New chapters have been added on the pathogenesis of endocrine tumors and on autoimmunity, and nine chapters have new authors.

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