Wilson's Disease: A Clinician's Guide to Recognition, Diagnosis, and Management / Edition 1

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Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is referred to you, will you appropriately recognize the possibility that the underlying diagnosis may be Wilson's disease? Wilson's disease is both treatable and reversible, and commonly misdiagnosed. This book aims to change this with comprehensive coverage of every aspect of Wilson's disease, from well-catalogued, easy-to-use clinical diagnostic tools to treatment methods to molecular biology.
Dr. Brewer is the world's leading expert on Wilson's disease, seeing and caring for over 300 patients with the disease during the last 20 years. He is a professor of human genetics at the University of Michigan.

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Editorial Reviews

Doody's Review Service
Reviewer: Amarish A Dave', D.O.(University of Illinois at Chicago College of Medicine)
Description: The book presents an overall clinical approach to Wilson's disease, from recognition to management.
Purpose: The purpose is to provide a concise review of Wilson's disease. This is a treatable disease if caught early and increasing the clinician's awareness of its early signs is important. The book accomplishes this objective.
Audience: "The book is written so that it is easily read by students and clinicians. The author writes in a confident and competent manner and seems to be a credible authority on this topic. "
Features: The book addresses Wilson's disease from a clinician's standpoint. First, the author describes the early identifying clinical features and how to evaluate them. Then, he goes into the detailed workup of the disease and, finally, management. The book's strength is that it is clearly written and at a level that can be appreciated by students through attending neurologists. Illustrations of Kayser-Fleischer rings are valuable as well.
Assessment: This is a good quality, concise reference for Wilson's disease. The book could be strengthened by the inclusion of additional information on some of the other metabolic/inherited diseases that may mimic Wilson's disease, without going into great detail, but enough to provide the clinician with a more comprehensive understanding of mimickers.
From The Critics
Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, psychiatrists, and even general internists respected enough to have especially difficult diagnostic cases referred to them, are among the clinicians Brewer (human genetics, U. of Michigan) thinks should know more about the diagnosis and available treatments for the disease. Rather then a complete technical treatise on it, he provides them a simple outline to guide them through recognition, diagnosis, and treatment. He even suggests that clinicians not currently treating a patient with Wilson's can read just the recognition parts, then fill in the details if and when the occasion arises. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780792373544
  • Publisher: Springer US
  • Publication date: 5/31/2001
  • Edition description: 2001
  • Edition number: 1
  • Pages: 190
  • Product dimensions: 6.20 (w) x 9.20 (h) x 1.00 (d)

Table of Contents

List of Figures. List of Tables. Foreword. Preface. Acknowledgements. 1. Overview of the Disease for the Clinician. 2. The Clinician's Challenge: Recognizing Wilson's Disease. 3. Simple Approaches to Screening and Definitive Diagnosis. 4. Description of the Anticopper Drugs Which are Used in Wilson's Disease Therapy. 5. Overview of Management for the Clinician: What's Important and What's Not. 6. Initial Treatment of Patients Who Present with Liver Disease. 7. Initial Treatment of Patients Who Present with Neurologic and/or Psychiatric Disease. 8. Maintenance Therapy. 9. Therapy of the Presymptomatic, the Pediatric, and the Pregnant Patient. 10. Risk Factors During Maintenance Therapy and Prognosis. 11. Disease Pathogenesis and Genetics. 12. Disease Pathology. 13. History, Important Milestones, and the Future. Index.
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