Windows to the Brain: Insights From Neuroimaging

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Overview

Windows to the Brain is the only book to synthesize neuroanatomical and imaging research as it pertains to selected neuropsychiatric diseases, containing all of the "Windows to the Brain" papers published from 1999-2006 in the Journal of Neuropsychiatry and Clinical Neurosciences. These reader-friendly summaries by more than sixty contributors present modern imaging techniques that assist in the diagnosis of neuropsychiatric illness, enhanced by easily understood color graphics of the neuroanatomical circuits of behavior, memory, and emotion. They provide a basic understanding of how to apply a variety of imaging techniques to the study of adult neuropsychiatric disease and how to use neuroimaging to assist in diagnostic work-ups for conditions ranging from sleep disorders to epilepsy to borderline personality.

Integrated, color-coded graphics present functional anatomical information in a manner that promotes understanding and use in clinical practice, while the text encompasses a wide range of diseases and injuries across the adult lifespan. The book is organized into four sections that will help readers increase their appreciation of the wide range of research and clinical applications for imaging in neuropsychiatry: chapters on imaging techniques discuss underlying principles, strengths and weaknesses, and applications; chapters on specific diseases demonstrate a range of investigative techniques; anatomy/circuit chapters focus on particular brain structures or functional neuropsychiatric circuits; and final chapters present image-based approaches to understanding or selecting treatment options. Some of the applications described are: • Use of fMRI in posttraumatic stress disorder to reveal the delicate balance between the structures of the emotion and memory tracks;• Use of high-resolution MRI and nuclear imaging to distinguish between panic disorder and simple partial seizure disorder;• Use of functional imaging studies to detect corticobasal degeneration, as a means of better understanding dementia;• Use of newer imaging techniques in identifying progressive multifocal leukoencephalopathy, to enable more rapid and reliable tailoring of individual therapy for HIV;• Use of functional neuroimaging in the study of fear, in order to better understand and treat anxiety-based psychiatric disorders;• Use of neuroimaging studies in conversion disorder, showing implications for the disruption of selfhood in dissociative identity disorder and schizophrenia;• Use of FDG-PET scans to look for predictors of treatment response in childhood-onset obsessive-compulsive disorder. Windows to the Brain can help bring less-experienced readers up to speed on advanced imaging and anatomical details that pertain to the modern practice of neuropsychiatry. It is must-reading for specialists in neuropsychiatry and cognitive/behavioral neurology, or for general psychiatrists with an interest in neuroimaging.

American Psychiatric Publishing

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Editorial Reviews

The Journal of Nervous and Mental Disease
This book is a" must have" collection of 32 chapters, each only 5 to 10 pages long, packed full if numerous colorful imaging that bring light different imaging techniques used ti answer specific questions related to understanding the pathophysiology, diagnostic specificity, and treatment of various neuropsychiatric disorders.
The journal of Nervous and Mental Disease

This book is a" must have" collection of 32 chapters, each only 5 to 10 pages long, packed full if numerous colorful imaging that bring light different imaging techniques used ti answer specific questions related to understanding the pathophysiology, diagnostic specificity, and treatment of various neuropsychiatric disorders.

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: The brain is the organ of the mind and the final common pathway for all behavior. As such, all mental processes derive from brain processes and psychopathology, which are neuropsychiatric symptoms that are manifestations of brain dysfunction. This informative book is emblematic of this current conceptual paradigm in the understanding of brain-behavior relationships and their importance in the diagnosis and treatment of psychiatric disorders. Written and edited by nationally recognized clinicians, researchers, and educators, this is an outstanding contribution to the field of psychiatry.
Purpose: The purpose, according to the editors, "is to bring that excitement and new knowledge to our clinicians and to our patients." The editors note, "(M)ost practicing psychiatrists, at that point in time (when the series "Windows to the Brain" began in the Journal of Neuropsychiatry and Clinical Neurosciences), had limited training in and understanding of how to use radiologic tools in mental health. Thus the need to educate clinicians in order to apply this knowledge became imperative." Indeed the editors and chapter authors have produced an excellent educational tool for trainees and practicing psychiatrists.
Audience: Although the intended audience is mainly neuropsychiatrists, psychiatrists in all subspecialties as well as neurologists interested in cognition and behavior would benefit from reviewing this book. It would also be helpful to candidates for the board examination in behavioral neurology and neuropsychiatry.
Features: Part 1 covers imaging techniques with informative reviews on cerebral blood flow, functional MRI, neuroimaging of ecstasy, white matter proton conductivity with diffusion tensor imaging, cortical inhibition in alcohol dependence, magnetoencephalography in autism, xenon CT imaging in psychiatry, and brain imaging in Huntington disease. Part 2 focuses on specific illnesses seen by most neuropsychiatrists with helpful chapters on fit versus panic attack, state versus trait in bipolar disorder, blast related traumatic brain injury, mild traumatic brain injury, axonal injury as mechanism of deficits in TBI, corticobasalganglionic degeneration, metachromatic leukodystrophy and psychosis, HIV leukoencephalopathy, prion disease, carbon monoxide poisoning, Binswanger disease, normal pressure hydrocephalus, and multiple sclerosis. Anatomy and brain circuitry is detailed in part 3 with chapters on sleep, fear and anxiety, rabies and the cerebellum, conversion hysteria, the limbic thalamus, emotional dysregulation in borderline personality disorder, central pain and neuroanatomy, and estrogen and higher cognitive function. Part 4 contains excellent reviews of obsessive-compulsive disorder and predicting treatment response, schizophrenia, and neurosurgical interventions for psychiatric disorders. There are beautiful diagrams and images throughout the book. The detailed index is quite helpful.
Assessment: This is an outstanding book, taken from the "Windows to the Brain" series from the Journal of Neuropsychiatry and Clinical Neurosciences. No neuropsychiatrist should be without a copy.
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Product Details

  • ISBN-13: 9781585623020
  • Publisher: American Psychiatric Publishing, Incorporated
  • Publication date: 1/30/2008
  • Edition description: New Edition
  • Pages: 263
  • Product dimensions: 8.50 (w) x 11.00 (h) x 0.75 (d)

Meet the Author

Robin A. Hurley, M.D., is Associate Chief of Staff at the W.G. "Bill" Hefner VAMC in Salisbury, North Carolina, and Associate Professor in the Departments of Psychiatry and Radiology at Wake Forest University School of Medicine, Winston--Salem, North Carolina and Baylor College of Medicine in Houston, Texas.

Katherine H. Taber, Ph.D., is a Research Health Scientist at the W.G. "Bill" Hefner VAMC in Salisbury, North Carolina, and Research Professor in the Division of Biomedical Sciences at the Edward Via Virginia College of Osteopathic Medicine in Blacksburg, Virginia.

American Psychiatric Publishing

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Table of Contents

Foreword. Preface. Imaging Technique. Blood flow imaging of the brain: 50 years' experience. Functional magnetic resonance imaging: application to posttraumatic stress disorder. Ecstasy in the brain: a model for neuroimaging. The future for diffusion tensor imaging in neuropsychiatry. Cortical inhibition in alcohol dependence. Application of magnetoencephalography to the study of autism. Applications of xenon computed tomography in clinical practice: detection of hidden lesions. New techniques for understanding Huntington's disease. Specific Diseases. Sudden onset panic: epileptic aura or panic disorder? Bipolar disorder: imaging state versus trait. Blast-related traumatic brain injury: what is known? Mild traumatic brain injury: neuroimaging of sports-related concussion. Traumatic axonal injury: novel insights into evolution and identification. Functional imaging as a window to dementia: corticobasal degeneration. Metachromatic leukodystrophy: a model for the study of psychosis. Identification of HIV-associated progressive multifocal leukoencephalopathy: magnetic resonance imaging and spectroscopy. The expanding role of imaging in prion disease. Applications of functional imaging to carbon monoxide poisoning. Binswanger's disease: an ongoing controversy. Normal pressure hydrocephalus: significance of magnetic resonance imaging in a potentially treatable dementia. Neuropsychiatric presentation of multiple sclerosis. Anatomy and Circuitry. Functional neuroanatomy of sleep and sleep deprivation. Neural underpinnings of fear and its modulation: implications for anxiety disorders. Rabies and the cerebellum: new methods for tracing circuits in the brain. Conversion hysteria: lessons from functional imaging. The limbic thalamus. Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging. Functional anatomy of central pain. An update on estrogen: higher cognitive function, receptor mapping, neurotrophic effects. Treatment. Predicting treatment response in obsessive-compulsive disorder. Schizophrenia: what's under the microscope? Surgical treatment of mental illness: impact of imaging. Index.

American Psychiatric Publishing

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