Withrow and MacEwen's Small Animal Clinical Oncology / Edition 5

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With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology.

"I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK

  • Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist.
  • A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies.
  • A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients.
  • Nearly 500 color images provide accurate depictions of specific diseases and procedures.
  • Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment.
  • Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology.
  • Chemotherapy protocols are included when case studies prove clinical efficacy.
  • Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet’s pain and nutritional complications as well as the pet owner’s grief when treatment is not successful.
  • Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases.
  • NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development.
  • NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts.
  • NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Heidi Phillips, BA, VMD (University of Illinois College of Veterinary Medicine)
Description: This book provides up-to-date, state-of-the-art information on all aspects of comparative oncology, from the epidemiology and known causes of cancer in companion animals to the latest in diagnostic and therapeutic modalities. The previous edition was published six years ago.
Purpose: The purpose is to detail the most recently proposed and confirmed mechanisms of disease and treatment of disease. New information pertaining to cancer biology, cancer epidemiology, and clinical trials is especially helpful.
Audience: Written for students and practitioners of veterinary medicine, the book is a highly useful aid for the study and management of oncological disease by all who are engaged in the study or practice of veterinary medicine, from students and general practitioners to boarded specialists. The authors are authorities in the fields of veterinary oncology, pathology, and surgery.
Features: The book successfully covers all areas of cancer biology and treatment, and provides succinct and informative summaries of known epidemiology and risk factors for the development of many cancers. Of special note is the completeness of the chapter dedicated to paraneoplastic conditions, which is unique aspect to this book. Special attention also is given to supportive care of cancer patients and to client education, often the most difficult tasks faced by veterinarians treating cancer in companion animals.
Assessment: This is a timely and thorough update that provides an accurate, inclusive summary of clinical studies and recommendations for practitioners treating cancers of all kinds in companion animals. The attention paid to the peripheral aspects of cancer diagnosis and management, such as the recognition and treatment of paraneoplastic conditions, is noteworthy.
From the Publisher

"The book is nicely spilt into sections and then into chapters. It is easy to find what you are looking for, be it some background science and explanation regarding cancer therapies, or information on a more specific tumour type. The book begins with a discussion of the basic science and principles of oncology, including surgery, chemotherapy and radiotherapy. This is explained nicely but simply, and is well illustrated throughout...In summary, this book covers the main tumours in good depth; it is a useful reference for the basic principles of vetrinary oncology and is certainly recommended for the practice bookshelf. The new edition provides new material that enhances its usefulness."

Veterinary Record, May 2013

"This book is the ideal companion for the vet wishing to understand disease and the best way to deal with it including communication to the client, complementary and alternative medicine and developmental therapeutics. A large part of the book remains focused on specific malignancies according their location."

Royal Canin, Vet's - Today, December 2013

"This book is amazing! I find it very hard to be critical, so I have stopped trying and am just putting pen to paper and writing what I think. If you have an interest in oncology and some spare time to concentrate whilst reading, buy this book. If you are a resident studying oncology, learn this book and you will pass your exams. The amazing thing about this book compared to any other veterinary text book I have ever read is that not only is it an authoritative and extremely contemporary resource, it also manages to convey a critical appraisal of all of the relevant veterinary literature without lapsing into the language of critique. I have tried to find fault with this book by checking for popular misrepresentations of the veterinary oncology literature. Where there is a valid controversy, all sides are represented without bias and without necessarily giving air to the notion that a controversy exists. I cannot find fault.

One of the really striking things about this book is that it is so up to date. There is a significant time lag between starting a project, identifying editors, instructing chapter authors, giving deadlines, chasing authors, reviewing deadlines, editing text, proofing and publishing. I always used to say that any textbook is two years out of date by the time it reaches the shelves. However, this book is considerably more contemporary than I expected. This must, in part, be due to the excellent choices of author for the various chapters included. These individuals are known to be leaders in their fields. It must also be reflection of the hard work of the editorial and production teams.

You know a reviewer is reaching desperation point when they discuss the pictures in only the third paragraph (unless it is a book that is based upon illustrations). The diagrams in the early chapters are clear and are appropriate. Cytology images are clear and useful. Photographs add to the overall quality of the book and break up the words striking a victory for the production team. Graphs are used to illustrate outcomes in a manner that could not be achieved without them.

I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it."

Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK

Barbara E. Kitchell
This textbook of veterinary cancer medicine is a clinically oriented resource. The first 14 chapters are general overviews of selected topics; the remaining chapters deal with specific tumor types. The prior edition was published in 1989 with the title Clinical Veterinary Oncology. The objectives are to provide a textbook that corrects what they describe as historically...strong opinions based on weak data. In the second edition, the objectives are expanded to be ...a state of the art book with an emphasis on biologic behavior and treatment of cancer in small animals. These objectives are worthy, and this edition represents a much-needed resource for veterinarians. For the most part, the objectives are met. The emphasis on exclusion of protocols based on weak data, although important, leaves some treatment areas lightly covered. Veterinary students, practitioners, and veterinary oncologists are the intended audience, according to the authors. The book meets the needs of this audience, although oncology specialists may find some of the material superficial. The editors are highly respected in the field of veterinary oncology. The selection of contributing authors adds depth to the material. Illustrations are black-and-white photographs and line drawings, which are appropriate in amount and quality. The references included are excellent and current. The authors have done a fine job with regard to references. The table of contents and index are well organized and adequate. The book is larger than the previous edition, and the cover design is improved. This second edition represents a substantial improvement and a much-needed reference resource. The bookis well written and exceptionally well referenced. The initial chapters are insightful, well-written overviews of principles of cancer biology, diagnosis, and therapy. The disease-specific chapters present the most current reviews of treatment protocols available. This book is a worthwhile addition to any practicing veterinarian's library.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781437723625
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/29/2012
  • Edition description: New Edition
  • Edition number: 5
  • Pages: 768
  • Sales rank: 901,200
  • Product dimensions: 8.70 (w) x 11.00 (h) x 0.80 (d)

Table of Contents

Why Worry About Cancer in Pets?


1. The Etiology of Cancer

1A. Genetic Factors

1B. Chemical, Physical, and Hormonal

1C. Cancer-Causing Viruses

2. Tumor Biology and Metastasis

3. The Pathology of Neoplasia

4. The Epidemiology and Incidence of Cancer

5. Paraneoplastic Syndromes


6. Diagnostic Imaging in Oncology

7. Diagnostic Cytology in Clinical Oncology

8. Molecular Diagnostics

9. Biopsy Principles and Staging


10. Surgical Oncology

11. Cancer Chemotherapy

12. Radiation Therapy

13. Immunotherapy of Cancer

14. Molecular/Targeted Therapy of Cancer

14A. Gene Therapy for Cancer

14B. Signal Transduction and Cancer

14C. Anti-angiogenic & Metronomic Treatment

14D. Emerging Therapeutics

15. Miscellaneous Treatments for Solid Tumors

15A. Management of Chronic Cancer Pain

15B. Nutritional Management of the Cancer Patient

15C. Client Grief Support

16. Complementary and Alternative Medicine for Patients with Cancer

17. Clinical Trials NEW!


18. Tumors of the Skin and Subcutaneous Tissues

19. Melanoma NEW!

20. Mast Cell Tumors

21. Soft Tissue Sarcomas

22. Cancer of the Gastrointestinal Tract

22A. Oral Tumors

22B. Salivary Glanc Cancer

22C. Esophageal Cancer

22D. Exocrine Pancreatic Cancer

22E. Gastric Cancer

22F. Hepatobiliary Tumors

22G. Intestinal Tumors

22H. Perianal Tumors

23. Tumors of the Respiratory System

23A. Cancer of the Nasal Planum

23B. Canine Nasosinal Tumors

23C. Cancer of the Larynx and Trachea

23D. Pulmonary Neoplasia

24. Tumors of the Skeletal System

25. Tumors of the Endocrine System

26. Tumors of the Female Reproductive System

27. Tumors of the Mammary Gland

28. Tumors of the Male Reproductive System

29. Tumors of the Urinary System

30. Tumors of the Nervous System

31. Ocular Tumors

32. Hematopoietic Tumors

32A. Canine Lymphoma and Lymphoid Leukemia

32B. Feline Lymphoma and Leukemia

32C. Canine Acute Myeloid Leukemia, Chronic Myeloproliferative Diseases, and Myelodysplasia

32D. Plasma Cell Neoplasms

33. Miscellaneous Tumors

33A. Hemangiosarcoma

33B. Thymoma

33C. Canine Transmissible Venereal Tumor

33D. Mesothelioma

33E. Neoplasia of the Heart

33F. Histiocytic Diseases

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