Xenotransplantation

by Carolyn Wilson (Editor), Daniel R. Salomon (Editor)

Overview

Xenotransplantation could have an impact on at least three aspects of medicine. The first is as a means of overcoming a severe shortage of human donor organs for the treatment of organ failure. The second aspect relates to the possibility that a xenogeneic organ would not be susceptible to infection by a "human" virus and thus the xenograft might resist injury caused by such viruses. The third and, as of yet, unexplored aspect relates to a means of delivering genes for therapeutic purposes thus overcoming some of the limitations of "conventional" gene therapy.

Product Details

ISBN-13:	9783540002109
Publisher:	Springer Berlin Heidelberg
Publication date:	09/10/2003
Series:	Current Topics in Microbiology and Immunology , #278
Edition description:	2003
Pages:	257
Product dimensions:	6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Genetic Modification of Xenografts.- Public Health Risks — Patient vs. Society in an Emerging Field.- Cross-Species Infections.- Non-Human Primate Herpesviruses: Importance for Xenotransplantation.- Understanding Xenotransplantation Risks from Non-Human Primate Retroviruses.- Exogenous Porcine Viruses.- Swine Hepatitis E Virus: Cross-Species Infection and Risk in Xenotransplantation.- Molecular Cloning and Functional Characterization of Infectious PERVand Development of Diagnostic Tests.- Xenotransplantation — Federal Regulatory Considerations.