Yeast Gene Analysis

Yeast Gene Analysis

by Elsevier Science
     
 

Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies

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Overview

Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.

New chapters on:
• strain construction
• genome-wide two-hybrid approaches
• use of microarrays for transcript analysis
• real-time analysis of chromosome behaviour and FRET
• synthetic gene array technology and protein arrays
• chemical genomics and yeast prions
• RNA gene analysis and mitochondrial gene function analysis
• phylogenetic footprinting
• discovering human gene function and predicting yeast gene function

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Editorial Reviews

From the Publisher
Praise for the Volume
"The book is far more than a cookbook: it seeks to place techniques and experimental strategies in some critical perspective, and expert investigators provide an overview of the state of the art in many areas... it is a compendium packed with information, insights, and discussions of potential pitfalls and limitations, all provided by experienced practitioners. The book successfully brings together a diffuse literature on sets of tools, technologies, and know-how in an accessible format and represents a sound investment for anyone interested in gene analysis."
—YEAST
"This is another excellent addition to the Methods in Microbiology Series... This is an outstanding resource for both investigators and graduate students working in the field of yeast gene function."
—DOODY'S PUBLISHING REVIEWS
Praise for the Series
"An invaluable resource for the detailed analysis of cellular gene function and genome architecture."
—NATURE

Product Details

ISBN-13:
9780123694799
Publisher:
Elsevier Science
Publication date:
09/04/2007
Series:
Methods in Microbiology Series
Pages:
730
Product dimensions:
6.60(w) x 9.60(h) x 1.40(d)

Meet the Author

Alistair Brown has led an active research group in yeast molecular biology for over 15 years. Having started at Glasgow University, his group is now based at Aberdeen University, studying gene function and regulation in Saccharomyces cerevisiae and the control of morphogenesis in Candida albicans. The Aberdeen Candida Group is now one of the largest academic groups studying the molecular physiology of C. albicans.

Mick Tuite is a Professor of Molecular Biology in the Department of Biosciences at the University of Kent, UK He has published over 100 research papers and reviews in the area of yeast molecular biology and genetics and is a member of the editorial board of the journals Yeast and Molecular Microbiology.

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