Table of Contents
Contributors vii
Preface ix
Structure and Regulation of Type 2 Transglutaminase in Relation to Its Physiological Functions and Pathological Roles 1 Carlo M. Bergamini, Russell J. Collighan, Zhuo Wang, and Martin Griffin
Physiopathological Roles of Human Transglutaminase 2 47 Vittorio Gentile
Transglutaminase in Epidermis and Neurological Disease or What Makes a Good Cross-Linking Substrate 97 Guylaine Hoffner, Amandine VanHoutteghem, William Andre, and Philippe Djian
Transglutaminase 2: A New Paradigm for NF-B Involvement in Disease 161 Soo-Youl Kim
Transglutaminase 2 At the Crossroads between Cell Death and Survival 197 Mauro Piacentini, Manuela D’Eletto, Laura Falasca, Maria Grazia Farrace, and Carlo Rodolfo
Tissue Transglutaminase and Its Role in Human Cancer Progression 247 Bo Li, Richard A. Cerione, and Marc Antonyak
Transglutaminase 2 Dysfunctions in the Development of Autoimmune Disorders: Celiac Disease and TG2−/−Mouse 295 Zsuzsa Szondy, Ilma Korponay-Szabo, Robert Kiraly, and Laszlo Fesus
Effects and Analysis of Transglutamination on Protein Aggregation and Clearance in Neurodegenerative Diseases 347 Zoltan Nemes
Transglutaminase-Mediated Remodeling of the Human Erythrocyte Membrane Skeleton: Relevance for Erythrocyte Diseases with Shortened Cell Lifespan 385 Laszlo Lorand, S. N. Prasanna Murthy, Anwar A. Khan, Weihua XUE, Oksana Lockridge, and Athar H. Chishti
Irreversible Inhibitors of Tissue Transglutaminase 415 Jeffrey W. Keillor, Nicolas Chabot, Isabelle Roy, Amina Mulani, Olivier Leogane, and Christophe Pardin
Methionine Adenosyltransferase (S-Adenosylmethionine Synthetase) 449 María A. Pajares and George D. Markham
Index 523
