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Lung Cancer

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Lung Cancer

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Overview

Lung cancer is a major cause of cancer-related deaths in men and women. However, since the first edition of Lung Cancer was published 14 years ago, rapid progress in the biology, prevention, diagnosis, and treatment of the disease has been made.

This outstanding team from the M.D. Anderson Cancer Center takes an evidence-based approach to lung cancer management and explains these advances in depth. Comprehensive treatment guidelines are provided, the third edition of Lung Cancer explores vital issues such as: Lung cancer susceptibility and risk assessment, The pathology and pathogenesis of peripheral lung adenocarcinoma including bronchioloalveolar carcinoma, Screening for early detection, Advances in molecular and genetic markers, The detection and treatment of pre-neoplastic lesions and screening for lung cancer, Novel therapies such as angiogenesis and multi-tyrosine kinase inhibitors. Lung Cancer is a concise summary of advances in lung cancer clinical research and treatment for the clinician and is an invaluable reference for respiratory physicians, medical oncologists, clinical and surgical oncologists.

Product Details

ISBN-13:	9781444358667
Publisher:	Wiley
Publication date:	08/26/2011
Sold by:	JOHN WILEY & SONS
Format:	eBook
Pages:	480
File size:	6 MB

About the Author

Jack A. Roth, MD FACS, Professor and Chairman, Bud Johnson Clinical Distinguished Chair, The University of Texas M.D. Anderson Cancer Center, Department of Thoracic & Cardiovascular Surgery and Professor of Molecular and Cellular Oncology, Director, W.M. Keck Center for Cancer Gene Therapy, Houston, Texas, USA.

James D. Cox, MD, Professor and Head, Division of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

Waun Ki Hong, MD, American Cancer Society Clinical Research Professor, Charles A. LeMistre Distinguished Chair in Thoracic Oncology and Professor and Chairman, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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Contributors     vii
Preface     xi
Smoking Cessation   Alexander V. Prokhorov   Kentya H. Ford   Karen Suchanek Hudmon     1
Lung Cancer Susceptibility Genes   Joan E. Bailey-Wilson     20
Lung Cancer Susceptibility and Risk Assessment Models   Xifeng Wu   Hushan Yang   Jie Lin   Margaret R. Spitz     33
The Molecular Genetics of Lung Cancer   David S. Shames   Mitsuo Sato   John D. Minna     61
Molecular Biology of Preneoplastic Lesions of the Lung   Ignacio I. Wistuba   Adi F. Gazdar     84
Detection of Preneoplastic Lesions   Stephen Lam     99
Treatment of Preneoplastic Lesions of the Lung   Annette McWilliams     111
The Pathology and Pathogenesis of Peripheral Lung Adenocarcinoma Including Bronchioloalveolar Carcinoma   Wilbur A. Franklin     121
Treatment of Bronchioloalveolar Carcinoma   Ji-Youn Han   Dae Ho Lee   Jin Soo Lee     144
Molecular Profiling for Early Detection and Prediction of Response in Lung Cancer   Jacob M. Kaufman   David P. Carbone     153
The Role for Mediastinoscopy in the Staging of Nonsmall Cell Lung Cancer   Carolyn E. Reed     169
Minimally Invasive Surgery for Lung Cancer   Michael Kent   Miguel Alvelo-Rivera   James Luketich     180
Extended Resections for Lung Cancer   Philippe G. Dartevelle   Bedrettin Yildizeli   Sacha Mussot     194
Adjuvant Chemotherapy Following Surgery for Lung Cancer   Benjamin Besse   Thierry Le Chevalier     221
Induction Chemotherapy for Resectable Lung Cancer   Katherine M.W. Pisters     233
Image-Guided Radiation Therapy   Kenneth E. Rosenzweig   Sonal Sura     247
Stereotactic Body Radiation Therapy for Lung Cancer   Robert D. Timmerman   Brian D. Kavanagh     256
Proton Therapy   Joe Y. Chang   Alfred R. Smith   James D. Cox     271
Combinations of Radiation Therapy and Chemotherapy for Nonsmall Cell Lung Carcinoma   Zhongxing Liao   Frank V. Fossella   Ritsuko Komaki     283
New Chemotherapeutic Agents in Lung Cancer   Anne S. Tsao     315
Immunologic Approaches to Lung Cancer Therapy   Jay M. Lee   Steven M. Dubinett   Sherven Sharma     334
Epidermal Growth Factor Receptor Inhibitors   Lecia V. Sequist   Thomas J. Lynch     352
Tumor Angiogenesis: Biology and Therapeutic Implications for Lung Cancer   Emer O. Hanrahan   Monique Nilsson   John V. Heymach     369
Retinoids and Rexinoids in Lung Cancer Prevention and Treatment   Nishin Bhadkamkar   Fadlo R. Khuri     386
Proteasome Inhibition in Nonsmall Cell Lung Cancer Therapy   Minh Huynh   Primo N. Lara Jr     400
Targeted Genetic Therapy for Lung Cancer   Jack Roth     411
Screening for Early Detection   James L. Mulshine     421
Natural Agents for Chemoprevention of Lung Cancer   Amir Sharafkhaneh   Suryakanta Velamuri   Seyed Javad Moghaddam   Vladimir Badmaev   Burton Dickey   Jonathan Kurie     441
Index     457

What People are Saying About This

From the Publisher

“The current edition builds on the strength of the previous editions … .Overall, the book was well planned. Each chapter is a concise review of the recent literature, with detailed references. Where warranted, there are tables, black-and-white diagrams, and photographs that expand on the information provided in the text. This well-organized book will be useful to pulmonologists, thoracic surgeons, radiation oncologists, medical oncologists, and others with an interest in lung cancer.” (New England Journal of Medicine, December 2008)

“One of the most comprehensive and up-to-date treatises that I have surveyed … .I would recommend the book highly to anyone in allied disciplines.” (Doody's Book Reviews)

From the B&N Reads Blog

Page 1 of

Editorial Reviews

3 Stars from Doody

This book attempts to describe the important basic science and clinical aspects of lung cancer. This is done in a standard format with chapters on the biology, evaluation, management, and detection of lung cancer by a number of accomplished authors in the field. This book was originally published five years ago. The editors' goal is to provide a succinct summary of the recent advances, both in basic research and clinical management, of the widening field of lung cancer. The scope and management of lung cancer has evolved dramatically in the last five years and an up-to-date version of this text is welcome. This book appropriately subdivides these important areas of research with attention given to preneoplastic lesions, as well as advances in the preoperative evaluation, surgical management, radiation techniques, and new developments in chemotherapeutic agents for this disease. A significant portion is devoted to new methods of detection of lung cancer including molecular techniques and immunologic and biologic approaches. The target audience includes clinicians, basic researchers, and clinical researchers in the field of lung cancer. It certainly will be appropriate for specialists in surgical oncology, medical oncology, radiation oncology, and possibly pulmonary medicine. The editors are highly accomplished clinicians and researchers in the field of lung cancer. The book is well organized. It includes basic science research and then progresses through chapters dealing with different management techniques including surgery, radiation, chemotherapy, and combined modality therapy. The text is well written, but there is a relative paucity of pictures, drawings, and graphics. Thevarious graphs and tables included, many of which are reproductions of prior work, are effective in presenting relevant data. The information is quite up-to-date, as much as is possible for a textbook, with references from within approximately 18 months available for each chapter. This book provides a clear but very brief table of contents and lacks any subheadings. It is presented in a relatively easy-to-read format with an attractive cover and large type. The appendix gives adequate references to various topics in standard fashion. This is an excellent review of the relevant basic science and clinical topics in lung cancer and would be an appropriate choice for any medical or scientific library and/or bookstore. It would also be a good reference in an oncology office and perhaps appropriate for some clinicians who deal specifically with lung cancer including surgeons, radiotherapists, or medical oncologists as well as basic science researchers in the field of lung cancer. I believe that the subject areas incorporate the important major topics in lung cancer with a possible exception of adequate description of screening, imaging, and pathology sections. These are not individually represented in the text.

Gregory A. Masters

A broad reference updated from the 1993 edition to include new developments but also to reflect the shift of emphasis in studies of the biology to factors influencing predisposition and the development of pre-neoplastic lesions. The topics include familiar predisposition, lung-sparing operations, surgery for small-cell lung cancer, three- dimensional conformal radiotherapy in bronchogenic carcinoma, new chemotherapeutic agents, chemoprevention, photodynamic therapy and thoracic malignancies, and genetic manipulations for treating lung cancer. Annotation c. by Book News, Inc., Portland, Or.

Booknews

Reviewer: Gregory A. Masters, MD (Evanston Hospital)
Description: This book attempts to describe the important basic science and clinical aspects of lung cancer. This is done in a standard format with chapters on the biology, evaluation, management, and detection of lung cancer by a number of accomplished authors in the field. This book was originally published five years ago.
Purpose: The editors' goal is to provide a succinct summary of the recent advances, both in basic research and clinical management, of the widening field of lung cancer. The scope and management of lung cancer has evolved dramatically in the last five years and an up-to-date version of this text is welcome. This book appropriately subdivides these important areas of research with attention given to preneoplastic lesions, as well as advances in the preoperative evaluation, surgical management, radiation techniques, and new developments in chemotherapeutic agents for this disease. A significant portion is devoted to new methods of detection of lung cancer including molecular techniques and immunologic and biologic approaches.
Audience: The target audience includes clinicians, basic researchers, and clinical researchers in the field of lung cancer. It certainly will be appropriate for specialists in surgical oncology, medical oncology, radiation oncology, and possibly pulmonary medicine. The editors are highly accomplished clinicians and researchers in the field of lung cancer.
Features: The book is well organized. It includes basic science research and then progresses through chapters dealing with different management techniques including surgery, radiation, chemotherapy, and combined modality therapy. The text is well written, but there is a relative paucity of pictures, drawings, and graphics. The various graphs and tables included, many of which are reproductions of prior work, are effective in presenting relevant data. The information is quite up-to-date, as much as is possible for a textbook, with references from within approximately 18 months available for each chapter. This book provides a clear but very brief table of contents and lacks any subheadings. It is presented in a relatively easy-to-read format with an attractive cover and large type. The appendix gives adequate references to various topics in standard fashion.
Assessment: This is an excellent review of the relevant basic science and clinical topics in lung cancer and would be an appropriate choice for any medical or scientific library and/or bookstore. It would also be a good reference in an oncology office and perhaps appropriate for some clinicians who deal specifically with lung cancer including surgeons, radiotherapists, or medical oncologists as well as basic science researchers in the field of lung cancer. I believe that the subject areas incorporate the important major topics in lung cancer with a possible exception of adequate description of screening, imaging, and pathology sections. These are not individually represented in the text.

Doody's Review Service

The current edition builds on the strength of the previous editions … .Overall, the book was well planned. Each chapter is a concise review of the recent literature, with detailed references. Where warranted, there are tables, black-and-white diagrams, and photographs that expand on the information provided in the text. This well-organized book will be useful to pulmonologists, thoracic surgeons, radiation oncologists, medical oncologists, and others with an interest in lung cancer.” (New England Journal of Medicine, December 2008)
“One of the most comprehensive and up-to-date treatises that I have surveyed … .I would recommend the book highly to anyone in allied disciplines.” (Doody's Book Reviews)

From the Publisher

Lung Cancer

Lung Cancer

eBook

eBook

Related collections and offers

Overview

Product Details

About the Author

Read an Excerpt

Table of Contents

What People are Saying About This

Customer Reviews

Related collections and offers

Overview

Product Details

About the Author

Read an Excerpt

Table of Contents

What People are Saying About This

Related Subjects

Customer Reviews