Adjuvant Therapy of Breast Cancer

Adjuvant Therapy of Breast Cancer

by I. Craig Henderson (Editor)

Paperback(Softcover reprint of the original 1st ed. 1992)

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Product Details

ISBN-13: 9781461365501
Publisher: Springer US
Publication date: 11/05/2012
Series: Cancer Treatment and Research , #60
Edition description: Softcover reprint of the original 1st ed. 1992
Pages: 464
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

I. Rationale and Methods for Studying Adjuvant Systemic Therapy.- 1. Evolving concepts in the adjuvant systemic therapy of operable breast cancer.- 2. Statistical methods for early breast cancer trials.- II. Results of Clinical Studies.- 3. The nature of the benefit.- 4. Adjuvant endocrine therapy of breast cancer.- 5. Adjuvant chemotherapy of axillary lymph-node-positive breast cancer.- 6. The node-negative problem: To treat or not to treat.- III. Special Problems.- 7. Defining the high-risk breast cancer patient.- 8. Models for weighing benefits and toxicities.- 9. Financial considerations in the use of adjuvant chemotherapy.- 10. The use of adjuvant therapy in patients treated with conservative surgery and radiotherapy.- 11. Treating the relapsed patient.- IV. Future Directions.- 12. Unanswered questions in the adjuvant therapy of breast cancer.- 13. Neoadjuvant chemotherapy.- 14. Altering cell kinetics with endocrine therapy.- 15. Polypeptide growth factors: Their potential value in the management of breast cancer patients.- 16. Immunotherapy of breast cancer.- 17. Breast cancer chemoprevention.- Appendices.- I. Consensus statements from panels convened by The National Cancer Institute in 1980, 1985, 1990.- II. List of completed and ongoing randomized clinical trials addressing questions related to the use of adjuvant systemic therapy to treat resectable breast cancer.

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