Pub. Date:
Elsevier Science
The Alkaloids: Chemistry and Biology

The Alkaloids: Chemistry and Biology

by Elsevier Science
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Product Details

ISBN-13: 9780124695610
Publisher: Elsevier Science
Publication date: 08/23/2005
Series: Alkaloids Series
Pages: 292
Product dimensions: 0.69(w) x 6.14(h) x 9.21(d)

About the Author

Professor Emeritus Geoffrey A. Cordell obtained his Ph.D. in synthetic natural product chemistry at the University of Manchester in 1970. After two years as a NATO postdoctoral fellow at the Department of Chemistry, M.I.T., he joined the College of Pharmacy, University of Illinois at Chicago (UIC). A Professor since 1980, he served as a Department Head for 12 years and as Interim Dean of the College of Pharmacy for almost three years, as well as holding several other senior academic and research administrative positions at the Department, College, and Campus levels. He was the Co-founder of the US - Thai Consortium for Pharmacy Education, which developed and trained faculty for six new schools of pharmacy in Thailand. He retired from the University of Illinois in 2007. Since 1983, he has served as President of Natural Products Inc., a consulting company.

He is the author of about 600 research publications, book chapters, comprehensive reviews and professional publications; is the author of two books, with three more in progress; the editor of 37 books, including 29 volumes in the series “The Alkaloids: Chemistry and Biology”; is Associate Editor-in-Chief of the Chinese Journal of Natural Medicines; and a member of the Editorial Advisory Board of 26 international scientific journals. He is a former President of the American Society of Pharmacognosy, and is also an Honorary Member.

In 1981, he was an Alexander von Humboldt Fellow at the University of Munich with Professor Hildebert Wagner. He is an elected Fellow of the Royal Chemical Society, the Linnean Society of London, the American Society of Pharmacognosy, and the American Association of Pharmaceutical Scientists. In addition to assisting international organizations and corporations in several countries around the world to develop their research and academic programs, he is an Honorary Professor at Sichuan University, Chengdu, China; and at Amity University, Noida, India. He is also a Visiting Professor at universities in Peru, Malaysia, and Brasil, and an International Collaborative Partner of the UTAR Global Research Network in Malaysia in the areas of biodiversity and cancer. In addition, he is a member of the International Advisory Board of several natural product research institutes. His interests include the chemistry and biosynthesis of alkaloids, the sustainability and quality control of medicinal agents, the remote detection of biologically active natural products, and the use of vegetables as chemical reagents.

Table of Contents

Contributors     vii
Preface     ix
Chemistry and Biology of Carbazole Alkaloids
Introduction     1
Occurrence, Isolation, and Structure Elucidation     3
Carbazole Alkaloids from Higher Plants     3
Carbazole Alkaloids from Other Sources     96
Biogenesis of Carbazole Alkaloids     159
Carbazole Alkaloids from Higher Plants     159
Carbazole Alkaloids from Other Sources     168
Biological and Pharmacological Activities of Carbazole Alkaloids     181
Anti-Tumor Active Carbazoles     181
Antibiotic Carbazoles     188
Anti-Viral Carbazoles     189
Anti-Inflammatory Carbazoles     190
Anti-Malarial Carbazoles     191
Diverse Pharmacologically Active Carbazoles     191
Chemistry of Carbazole Alkaloids     195
General Methods for Carbazole Construction     195
Total Syntheses of Carbazole Alkaloids     210
Addendum     385
References     391
Cumulative Index of Titles     411
Subject Index     419

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