Pub. Date:
Hogrefe Publishing
Allergy Frontiers and Futures: Proceedings of the 24th Symposium of the Collegium Internationale Allergologicum

Allergy Frontiers and Futures: Proceedings of the 24th Symposium of the Collegium Internationale Allergologicum

by J. B. Bienenstock, J. Ring, A. G. T. Togias


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Product Details

ISBN-13: 9780889372795
Publisher: Hogrefe Publishing
Publication date: 03/01/2004
Pages: 368
Product dimensions: 6.60(w) x 9.60(h) x 1.10(d)

Table of Contents

Genes and Environment
Functional Genomics of Allergic Disease: Lessons from IL-131
Pollen-Associated Lipid Mediators in the Elicitation of Allergic Reactions5
Epithelial Cell Innate Immune Responses to Rhinovirus Infection11
Release of Respirable Allergens into the Outdoor Air15
Influence of Pertussis/Pertussis Vaccination on Asthma and Allergy Prevalence in East and West Germany17
Relationship of the Cytokine SNPs and Clinical Characteristics in Children with Atopy25
The 3D Structure of the Calcium-Binding Pollen Allergen Phl p 729
Cas s 1, the Major Allergen from Castanea sativa Pollen31
Characterization of High and Low Molecular Weight Allergens from Celery34
The Major Allergen from Mugwort Pollen is a Defensin-like Glycoprotein37
Ana o 1 and Ana o 2, Major Cashew Allergens of the Vicilin and Legumin Families40
Der p 2 Contains a Universally Immunogenic T-Cell Epitope44
The Protein Families of Plant Food Allergens48
T-Cell Responses to the Allergens of the House Dust Mite51
Recombinant Allergens for the Diagnosis and Treatment of House Dust Mite Allergy55
Reconstructing the Repertoire of Storage Mite Allergens by Recombinant DNA Technology60
In-planta Production of Pollen Allergens63
T-Cells, Dendritic Cells
A Role for NKT Cells in the Regulation of Ongoing Type 2 Immune Responses?67
Notch Signaling in the Functional Differentiation of Peripheral CD4[superscript +] T-Cells71
Healthy Immune Response to Allergens76
The Role of CD8 T-Cells in Allergic Lung Inflammation79
The Role of Histamine in the Regulation of T-Cell and Antibody Responses82
Histamine Receptors on Human Monocyte-Derived Dendritic Cells87
Differential Expression of Transporter Proteins Involved in Drug Export in Human Macrophages Compared to Liver Cells91
Phenotype Differences in Monocyte-Derived Dendritic Cells from Nickel-Allergic and Nonallergic Donors upon Nickel Exposure93
Th1 Cytokine-Like Properties of Osteopontin on T-Cells, Macrophages, and Dendritic Cells in Type 1 Immune Responses97
Mast Cells, Basophils
Hemopoietic Mechanisms as Targets of Therapy in Rhinitis and Asthma103
MITF Mutants as the Third Mast Cell-Deficient Mice107
2-Arachidonyl Glycerol Inhibits the Immunological Activation of Human Basophils and of Guinea Pig Mast Cells110
Mast Cell Activation by Glycosphingolipids and Cholesterol113
Role of Mast Cells in Intestinal Inflammation Induced by Bacteria116
Spontaneous Development of Human Mast Cell Lines120
Inhibition of Mast Cell Activation by gp49B1123
Human Mast Cell Responses to Toll-Like Receptor Activators126
Expression and Function of Siglec-8 Isoforms in Human Eosinophils, Basophils, and Mast Cells130
Selective Downregulation of Fc[gamma]RI and Fc[epsilon]RI133
Increased Immunogenicity of Mast Cell-Associated Antigens138
Production of Nitric Oxide by Mast Cells and Effects on Their Activity142
Inhibition of Mast Cell Activation and Cytokine mRNA Expression by Nitric Oxide and Reactive Oxygen Species145
UV-Light Suppresses Histamine Release in Human Skin Mast Cells149
Functional Coupling of Fc[epsilon]RI Employs Two Proximal Src Family Kinases152
Eosinophils, Neutrophils
Membrane Fusion Events During Human Eosinophil Exocytosis157
IL-5 Induces Functional IL-2 Receptors on Eosinophils161
Role of Eosinophils in Angiogenesis164
Effects of Human Eosinophils on Cytokine Production by Lung Fibroblasts166
Dose-Dependent Secretion of IL-4 from Human Blood Eosinophils Ligated with Lectins169
Primary Eosinophilic Esophagitis172
Isolation of a Serine Threonine Kinase Interacting with the Cytoplasmic Tail of mIgE177
The Membrane Proximal Region of Fc[epsilon]RI[alpha]182
Construction of a Reporter Mouse Strain189
The Free Form of the [alpha]-Subunit of the High-Affinity IgE Receptor Is Rapidly Degraded but Stabilized by IgE192
Differing Structural Requirements for Fc[gamma]RIIA-Mediated Signaling Events197
Role of T-Cell Costimulatory Signals for Allergen-Induced Immune Reactions201
The Central Role of the Epithelium in Immune and Inflammatory Responses in the Airways208
Mitogen-Activated Protein Kinase in Airway Inflammation212
Mechanical Stress216
Bronchial Epithelial Cell and Epidermal Keratinocyte apoptosis220
Neuroimmune Dysbalance in Bronchial Asthma223
Sensory C-Fiber Nerve Responses to Allergic Mediators in Guinea Pig Airways228
Deep Inspiration-Induced Airways Distensibility and Physiologic Responses in Asthma233
Food Allergy and Anaphylaxis
Government Study on the Prevalence of Immediate Food Allergy237
Anaphylaxis in Children242
Antacid Medication245
Use of Recombinant Latex Allergens249
Diagnosis and Therapy of Latex Allergy with Recombinant scFv Antibody Fragments252
FAST Test to Assess Basophil Activation in Patients Allergic to Different Allergens255
Atopic Eczema, Allergic Skin Diseases
Atopy Patch Test with Biologically Standardized Aeroallergens and Food Allergens in Petrolatum259
Role of Costimulatory Signals for Cytokine Production of T-Cells in Atopic Dermatitis263
Expression of CD30[superscript +] and CD45[superscript +] RO in Acute Atopic Dermatitis Skin Lesions266
Tacrolimus Ointment Is Safe and Effective in the Treatment of Atopic Dermatitis269
The Role of Helicobacter pylori in the Pathogenesis of Chronic Urticaria272
IgE Crossreactivity Between Exogenous and Autologous Antigens Investigated by Basophil Histamine Release275
CD63 Expression on Basophils as a Tool for the Diagnosis of Food Allergy: Sensitivity and Specificity279
The Management of Mucosal Dysregulation Using Lactobacillus acidophilus (Lavri-1)283
Inhibition of Airway Remodeling, Cell Infiltration, and Airway Hyper-responsiveness287
IgE-Mimotopes Are Safe for Immunizations when Displayed in a Monovalent Manner292
Effect of Anti-IL-5 (Mepolizumab) on Airway Eosinophils in Asthmatics298
Priming Effect of Cysteinyl Leukotriene D[subscript 4] on Human Lung Macrophages302
Levocetirizine Modulates the Cellular Network of Allergic and Inflammatory Processes306
Food Allergy and Liver/Intestines310
Inhibition of IL-4Ra or STAT6 as Experimental Strategies for the Therapy of Atopic Diseases317
Induction of Antigen-Specific T-Cell Regulation Through Peptide Immunotherapy320
Biodegradable Nanospheres as Bet v 1 Delivery System for Immunizations of BALB/c Mice324
Prevention and Therapy of Th2-Type Responses327
Possible Adjuvant Activity of Yellow Jacket (Vespula vulgaris) Venom330
Evaluation of Hypoallergenic Allergen Variants Using CD203c Expression as a Measure of Basophil Activation332
Tolerance to Cats335
Oligodeoxynucleotides Containing CPG Motifs339
Allergen Immunotherapy: Immune Deviation or Anergy?342
Author Index347
Keyword Index351

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