The story of endorphinsthe body’s own morphine.
“Fascinating.” -- The New Yorker
The exciting story of the race to discover endorphinsopiate-like chemicals in the brainand their links to:
In late 1973, scientists John Hughes and Hans Kosterlitz spent the majority of their time in an underfunded, obscure, and cramped laboratory in Aberdeen, Sweden. While working on the brains of pigs, the duo discovered a nonaddictive narcotic chemical that they hoped to later find in human brains. If they could isolate this chemical in humans, perhaps they could find a way to help the world begin to heal itself. Hughes and Kosterlitz’s research would inevitably lead them to discover endorphins, the body’s own natural morphine and the chemical that makes it possible to feel both pain and pleasure.
Announcing their findings to the scientific world thrust Hughes and Kosterlitz in the spotlight and made them celebrities. Soon, scientists all over the world were hastily examining the human brain and its endorphins. In a few years’ time, they would use the team’s initial research to link endorphins to drug addiction, runner’s high, appetite control, sexual response, and mental illnesses such as depression and schizophrenia.
In Anatomy of a Scientific Discovery, Jeff Goldberg describes Hughes and Kosterlitz’s lives before, during, and after their historic and scientific breakthrough. He also takes a look at the bigger picture, revealing the brutal competition between drug companies to find a way to cash in on this monumental discovery.
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Table of Contents
Introduction to the Twenty-Fifth Anniversary Edition 1
Slaughterhouse Days 4
Brain Soup 11
Locks and Keys 22
Substance X 39
Breaking the Code 59
Alpha, Beta, Gamma 81
The Madness Factor 94
The Endorphin Business 115
Rats and Runners 144
The Symphony and the Orchestra 156