Animal Transgenesis and Cloning is a concise, balanced introductionto this dynamic subject, covering key issues and current techniquescurrently used in animal transgenesis and cloning. Whilst providingthe reader with the essentials of the subject, from the molecularbasis of gene structure and function to therapeutic gene cloning inhumans, social and ethical implications of this important area ofresearch are also considered.Written in a clear, accessible style, the book starts with anintroduction to key molecular biology techniques and in particular,considers techniques used specifically for cloning animals andgenerating transgenic animals. Later chapters examine the diversetheoretical, technical and ethical issues raised by cloning andtransgenesis in both animals and humans.Animal Transgenesis and Cloning:* Is an accessible, concise introduction to this dynamicfield* Discusses biological, technical and ethical issues related tocloning and transgenesis* Provides an up-to-date account of the latest research methods andapplications.Reviews'This is a proposal for a book translation in a field that isclearly of importance and very topical. The idea of the book, fromgene to transgenic animal, to its uses and abuses is sound andlogical ...... It is probable that I would suggest (using) a booksimilar to the one proposed' Dr Janet Smith, University ofBirmingham.'Chapter one was a tour de force! Very concise and admirably clear...... I was particularly impressed with the author's 2-pagesummary of eukaryotic gene regulation, which is no meanachievment!' Dr David de Pomerai, University of Nottingham.'...... I felt that this is a well written, topical book. It coversa lot of ground ...... in my opinion the author manages to providea satisfying amount of detail and a well focussed treatment of eachtopic. I like the logic of the book, the fact that it pullstogether all of the issues into one readable and manageable text'Dr Brendan Curran, Queen Mary, University of London.
|Product dimensions:||6.20(w) x 9.09(h) x 0.85(d)|
About the Author
Professor Louis Marie Houdebine is currently Director of Research at INRA (Institut National de la Recherche Agronomique) in Paris. More specifically he heads the 'Cell Differentiation' team whose research includes, amongst other things, using transgenic rabbits for the study of atherosclerosis and aids, and looking at how transgenic mice and rabbits expressing human and sheep PrP genes can be used to aid further research into Creutzfeld-Jacob disease and scrapie.Transgenese Animale et Clonage was first published in French by Dunod earlier this year. The French edition was designed to be a concise, introductory book of no more than 150 pages providing the reader with the essentials of the subject, i.e current research and applications of transgenesis and cloning, with limited technical details and references.
Table of Contents
Abbreviations and Acronyms.
1. FROM THE GENE TO THE TRANSGENIC ANIMAL.
The number of genes in genomes.
The major techniques of genetic engineering.
The systematic description of genomes.
Classical genetic selection.
Experimental mutation in genomes.
2. TECHNIQUES FOR CLONING AND TRANSGENESIS.
Techniques of animal transgenesis.
3. APPLICATIONS OF CLONING AND TRANSGENESIS.
Applications of animal cloning.
Applications of animal transgenesis.
4. LIMITS AND RISKS OF CLONING, GENE THERAPY ANDTRANSGENESIS.
Limits and risks of cloning.
Limits and risks of gene therapy.
Limits and risks of transgenesis.
Conclusion and Perspectives.