This volume 64 in the Annual Review of Biochemistry series covers a broad diversity of subjects including mycobacterial envelopes, triplex DNA structures, protein domains, voltage-gated ion channels, oligonucleotide functions, and the nuclear pore complex. Included is an autobiography of Peter Reichard that details, in a very personal manner, his career accomplishments in the fields of pyrimidine synthesis and ribonucleotide reductase. Of particular interest to the biochemist will be his description of his role in the Nobel Institute. The book represents a continuing effort to publish current, high quality reviews by the top experts in their fields. Each chapter contains an abstract, introduction, and summary that should be helpful in assessing the most recent advances. The reviews are valuable to researchers in biochemistry and molecular biology as well as to teaching faculty presenting courses with content in these areas. Although the reviews concentrate on new data accumulated within the last few years, most contain earlier reviews in their literature cited. The comprehensive lists of reviews detail the historic perspective permitting a student to gain insight into the progress of researchers and an understanding of future directions for the research. The volume contains a cumulative index of contributing authors and chapter titles from Volumes 60-64 of the Annual Review as well as a list of related articles in other Annual Reviews. The book contains numerous tables and black-and-white figures that enhance the content of each review. The list of references is extensive and includes earlier reviews and current publications, many from 1994. The appearance of the book is consistent withformer volumes of Annual Reviews. The table of contents and index are adequate. This volume is a mandatory addition to libraries of biochemistry departments for a comprehensive understanding of the status of current research.
This volume 66 in this outstanding review series contains the contributions of 52 experts in diverse fields of biochemistry, molecular biology, and other related areas. Topics presented among others are: mitochondrial DNA maintenance in vertebrates, molecular basis for membrane phospholipid diversity, regulation of phosphoenolpyruvate carboxykinase gene expression, and the ATP synthase, to name only four. The purpose of this volume is to review the status of selected currently important areas of biochemistry and related areas as to assess what future directions might be. Audiences for this volume are active researchers, teachers, and advanced students in biochemistry, molecular biology, and related areas. This volume has an abundance of current references and a subject and author index. It also includes cumulative indexes of contributing authors and chapter titles of volumes 62 to 66. This is another outstanding volume in this series that reflects a careful selection of topics and contributors. The printing is clear and consistent and there is little if any redundancy. This is a carefully planned and edited volume attractive in appearance and a useful addition to a personal or institutional library.
This volume represents a compendium of articles in the most active research areas in the field of biochemistry. It is the 1998 edition of the well-known Annual Reviews in Biochemistry series. The purpose is to present ""cutting edge"" review articles in the biochemistry field. It has been a long-standing tradition to publish such volumes every year. As usual, the articles are written by experts in their respective fields, and are of the highest caliber and authority. The audience is professionals and students in all biomedical and agricultural research areas, especially persons interested in the molecular aspects of biomedical sciences. The articles are largely concerned with molecular biology/molecular genetics and proteins with various biological activities. Personally, I decry the absence of articles on intermediary metabolism; this area has been the mainstay of the field of biochemistry. However, now it has been relegated to publications in the nutritional sciences area. Since one cannot cover everything in a volume with 800-900 pages, priorities must be established. As usual, this volume is sparse on illustrations, and the index is not very helpful. This publication is a well-established tradition in the biomedical research area. The 1998 volume continues this tradition of excellence, where content is of greater importance than appearance and glitzy illustrations. This volume belongs on the shelves of all libraries that specialize in biomedical book collections.
The books in the Annual Reviews series have long been recognized as classic presentations in their respective fields, and that of biochemistry, now in its 62nd year, is no exception. (The present reviewer must declare his interest, having been a contributor to the Annual Review of Physiology in 1949.) There are 19 chapters on a broad range of topics of which something over a third emanate from, or have their scientific roots in, departments or the discipline of molecular biology. The reviews update knowledge in each of the selected fields, and the references are good to 1992. The readership, it goes almost without saying, is biochemists, molecular biologists, and workers in allied fields of cell biology. These volumes belong in general and medical libraries and in departmental libraries of the mentioned fields. These articles are generally above the level of the student, resident, or general practitioner. However, a distinction can be made between closely focused articles and those that cover broader interests. Thus, the general biochemist or general scientist may find his or her interests best served by the chapters on human gene therapy, membrane partitioning during cell division, cytoplasmic motors, structure-based inhibitors of HIV-1 protease (still, alas, a promise only), pathways of protein folding, and tumor suppressive genes. A useful feature is the list of references to articles of biochemical interest appearing in other volumes of Annual Reviews. It is nevertheless not quite true that there is something for everybody in these sometimes extremely detailed and densely written chapters. An exception must, ofcourse, be made for the custom of presenting the ""Life"" of a distinguished ""older"" biochemist, in this volume that of Esmond E. Snell, who reviews his career of 55 years in biochemistry ""From Bacterial Nutrition to Enzyme Structure."" These essays certainly present a broader view of biochemical advance than can annual summations. However, incremental progress relies heavily on such summations.
Reviewer: Eugene A Davidson, PhD (Georgetown University School of Medicine)
Description: This is volume 70 of a yearly series that presents a set of selected reviews written by authorities in their respective areas. A broad range of topics are covered and each chapter has a thorough bibliography.
Purpose: The goal of this series is to provide a set of authoritative reviews for scientists working in the areas covered. This is a useful objective, and the current volume fulfills these goals.
Audience: The book is intended for practicing scientists who wish to have a comprehensive, current reivew of a particular area. The editors have selected appropriately qualified authors who meet these objectives well.
Features: As with prior volumes in this series, there is not a single organizing theme but rather a set of individual reviews. A very broad range of topics is covered, ranging from aspects of membrane fusion to evolution of enzyme function. The arrangement of the chapters follows no particular order since it is not intended that this volume be read in any defined sequence. Rather, the detailed material presented offers a resource for any investigator who has an interest in the topic and, as such, the reader will select those topics of value. The accompanying bibliographies are extensive and provide an additional resource. A chapter of interest to all, especially students, is a reminiscence written by Charles Yanofsky detailing his career path. Forty years ago, a book titled Annual Review of Biochemistry could be just that. Regrettably, the dramatic expansion of this field has made this a task beyond the scope of one volume. Nevertheless, the high standard of this book makes it a necessity for those in the field.
Assessment: The reviews in this volume have a well established format that maintains their value. Many other review volumes are available but do not substitute.