Affords researchers ready access to a vast body of information on identifying and isolating natural anticancer agents The authors open this valuable text/reference with an in-depth exploration of the vast potential of plant, animal, microorganism constituents as sources for new and effective anticancer, antiviral drugs. They update the literature on cancer-causing and related viruses with an emphasis on HIV. And they summarize the better known tumor promoters and carcinogens, and point out the fine line between antineoplastic and carcinogenic activity. The lion’s share of the book consists of an exhaustive compilation, in tabular form, of terrestrial and marine products. The first section covers terrestrial and marine plant and animal antineoplastic and cytotoxic constituents, organized by source. Within each chapter, entries are listed in order of molecular formula. Included are the more active synthetic and some semi synthetic analogs, with indications of which modifications are most likely to be useful. Also as an aid to quick reference, indexes provide access to entries by way of compound name, molecular weight, and species name. In the second section, the authors offer an exhaustive survey of marine plant and animal products, including both those with known biological activity and those without. As in the previous section, entries are listed according to molecular formula.
|Product dimensions:||7.28(w) x 10.24(h) x 1.38(d)|
About the Author
George R. Pettit, PhD, is Dalton Professor of Cancer Research, Regent’s Professor of Chemistry, and Director of the Cancer Research Institute of Arizona State University. He has received numerous awards for his research into anticancer drugs, including an Outstanding Investigator Award from the National Cancer Institute and a Chemical Pioneer Award from the American Institute of Chemists. Fiona Hogan Pierson, PhD, is Assistant Research Specialist with the Cancer Research Institute of Arizona State University. She holds degrees in organic chemistry from University College Dublin, Ireland. Cherry L. Herald, PhD, is Research Professor and Associate Director of the Cancer Research Institute of Arizona State University. Dr. Herald holds degrees in chemistry and organic chemistry from Arizona State University.
Table of Contents
Partial table of contents:
Cancer Causing and Related Lethal Viral Diseases.
Tumor Promoters and Carcinogens.
NEW BIOSYNTHETIC ANTINEOPLASTIC AND/OR CELL GROWTH INHIBITORY AGENTS.
Higher Plant Steroids.
Fungi and Other Lower Plant Biosynthetic Products.
Marine Algae Biosynthetic Products.
MARINE ANIMAL BIOSYNTHETIC PRODUCTS.
Hydrocarbons, Alcohols, and Esters.
Phenols, Quinones, and Related Compounds.
Amines and Nitrogen Heterocyclic Compounds.
MARINE PLANT BIOSYNTHETIC PRODUCTS.
Marine Plant Constituents.