ISBN-10:
0199638497
ISBN-13:
9780199638499
Pub. Date:
06/28/2002
Publisher:
Oxford University Press, USA
Apoptosis: The Molecular Biology of Programmed Cell Death

Apoptosis: The Molecular Biology of Programmed Cell Death

by Michael Jacobson, Nicola McCarthy
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Overview

Apoptosis is a regulated form of cell demise that can be induced or blocked by groups of specific stimuli. Occurring in all living tissues, it is thought critical to the maintenance of homeostasis and is implicated in lowering susceptibility to tumour growth. Conversely, over-sensitivity to apoptotic triggers can cause cells to be lost inappropriately from tissues, as appears to occur in neurodegenerative diseases. This book examines the molecular pathways regulating apoptosis, progressing from the nematode worm through Drosphila to the more complex pathways evident in mammalian cells. Differences in the cell death pathway within specific tissues are addressed, as are the different genes that may act to regulate progressive steps.

Product Details

ISBN-13: 9780199638499
Publisher: Oxford University Press, USA
Publication date: 06/28/2002
Series: Frontiers in Molecular Biology Series , #40
Edition description: New Edition
Pages: 346
Product dimensions: 9.70(w) x 7.60(h) x 0.80(d)

Table of Contents

Abbreviations

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