Apoptosome: An up-and-coming therapeutical tool

Apoptosome: An up-and-coming therapeutical tool


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Product Details

ISBN-13: 9789400790902
Publisher: Springer Netherlands
Publication date: 11/24/2014
Edition description: 2010
Pages: 322
Product dimensions: 6.10(w) x 9.25(h) x 0.03(d)

Table of Contents

1 Physiological and Pathological Role of Apoptosis Virve Cavallucci Marcello D' Amelio 1

2 Apoptosome Structure and Regulation Elisabetta Ferraro Claudia Fuoco Flavie Strappazzon Francesco Cecconi 27

3 Chemical Regulation of the Apoptosome: New Alternative Treatments for Cancer Kelvin Cain 41

4 Molecules That Bind a Central Protein Component of the Apoptosome, Apaf-1, and Modulate Its Activity Laura Mondrag?n Mar Orz?ez Anna Gortat Monica Sancho Angel Messeguer Mar?a Jes?s Vicent Enrique P?rez-Pay? 75

5 Regulation of Cell Death and Survival by RNA Interference - The Roles of miRNA and siRNA Paul Lingor 95

6 Beneficial Role of Taurine Against Myocardial Apoptosis During Ischemic Injury Takashi Ito Stephen W. Schaffer Junichi Azuma 119

7 BAG3 Protein: Role in Some Neoplastic Cell Types and Identification as a Candidate Target for Therapy Maria Pascale Alessandra Rosati Michelina Festa Anna Basile Morena d' Avenia Antonia Falco Gaetano Torino Maria Caterina Turco 137

8 Targeting Survivin in Cancer Therapy: Pre-clinical Studies Marzia Pennati Marco Folini Nadia Zaffaroni 147

9 Hsp 70 and Hsp 27: Emerging Targets in Cancer Therapy Anne Laure R?role Anne Laure Joly Dominique Thuringer Carmen Garrido 169

10 Role of the RNA-Binding Protein HuR in Apoptosis and Apoptosome Function Yuki Kuwano Imed-Eddine Gallouzi Myriam Gorospe 203

11 Acetylcholinesterase as a Pharmacological Target in Cancer Research Sang Eun Park Young Hyun Yoo 221

12 Putative Role of HCA66, A New Apaf-1 Interacting Protein, in the Physiopathology of NF1 Microdeletion Syndrome Patients Patricia Rigou Audrey Faye Jean-Luc Poyet 237

13 Cristae Remodeling and Mitochondrial Fragmentation: A Checkpoint for Cytochrome c Release and Apoptosis? Luca Scorrano 253

14 Apoptosome Pharmacological Manipulation: From Current Developments in the Laboratory to Clinical Implications Marcello D' Amelio Francesco Cecconi 271

15 The Therapeutic Role of Taurine in Ischaemia-Reperfusion Injury Ross Kingston 283

16 Targeting Survivin in Cancer Therapy: Clinical Considerations Tetsuhiro Tsuruma Hidekaz Kameshima Yuji Iwayama Toshihiko Torigoe Yoshihiko Hirohashi Noriyuki Sato Koichi Hirata 305

Index 321

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