Pub. Date:
Springer-Verlag New York, LLC
Atypical Parkinsonian Disorders: Clinical and Research Aspects / Edition 1

Atypical Parkinsonian Disorders: Clinical and Research Aspects / Edition 1

by Irene Litvan


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A comprehensive review of what is known not only about the cause and treatment of atypical parksonian disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors cover the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions.

Product Details

ISBN-13: 9781588293312
Publisher: Springer-Verlag New York, LLC
Publication date: 03/02/2005
Series: Current Clinical Neurology
Edition description: 2005
Pages: 512
Sales rank: 650,891
Product dimensions: 7.01(w) x 10.00(h) x 0.04(d)

Table of Contents

What is an Atypical Parkinsonian Disorder?

Irene Litvan

Historical Issues and Atypical Parkinsonian Disorders

Christopher G. Goetz

Epidemiology of Progressive Supranuclear Palsy and Multiple System Atrophy

Adam Zermansky and Yoav Ben-Shlomo

Neuropathology of Atypical Parkinsonian Disorders

Ian R. A. Mackenzie

Animal Models of Tauopathies

Jada Lewis and Michael Hutton

Neurodegenerative a-Synucleinopathies

Michel Goedert and Maria Grazia Spillantini

Computer Modeling in Basal Ganglia Disorders

José Luis Contreras-Vidal

Atypical Parkinsonian Disorders: Neuropathology and Nosology

Charles Duyckaerts

Genetics of Atypical Parkinsonism: Implications for Nosology

Thomas Gasser

Medical History and Physical Examination in Parkinsonian Syndromes: How to Examine a Parkinsonian Syndrome

Marie Vidailhet, Frédéric Bourdain, and Jean-Marc Trocello

Role of Neuropsychiatric Assessment in Diagnosis and Research

Dag Aarsland, Uwe Ehrt, and Clive Ballard

Added Value of the Neuropsychological Evaluation for Diagnosis and Research of Atypical Parkinsonian Disorders

Bruno Dubois and Bernard Pillon

Role of Praxis in Diagnosis and Assessment

Ramón Leiguarda

Role of Visuospatial Cognition Assessment in the Diagnosis and Research of Atypical Parkinsonian Disorders

Paolo Nichelli and Anna Magherini

Role of Ocular Motor Assessment in Diagnosis and Research

R. John Leigh and David S. Zee

Characterizing and Assessing Speech and Language Disturbances

Carol Frattali and Joseph R. Duffy

Quality of Life Assessment in Atypical Parkinsonian Disorders

Anette Schrag and Caroline E. Selai

Progressive Supranuclear Palsy

Irene Litvan

Corticobasal Degeneration: The Syndrome and the Disease

Bradley F. Boeve

Multiple System Atrophy

Felix Geser and Gregor K. Wenning

Clinical Diagnosis of Dementia With Lewy Bodies

David J. Burn, Urs P. Mosimann, and Ian G. McKeith

Clinical Diagnosis of Familial Atypical Parkinsonian Disorders

Yoshio Tsuboi, Virgilio H. Evidente, and Zbigniew K. Wszolek

Clinical Diagnosis of Vascular Parkinsonism and Nondegenerative Atypical Parkinsonian Disorders

Madhavi Thomas and Joseph Jankovic

Role of Electrophysiology in Diagnosis and Research in Atypical Parkinsonian Disorders

Josep Valls-Solé

Role of CT and MRI in Diagnosis and Research

Mario Savoiardo and Marina Grisoli

Role of Functional Magnetic Neuroimaging in Diagnosis and Research

Hartwig Roman Siebner and Günther Deuschl

PET and SPECT Imaging in Atypical Parkinsonian Disorders

Alexander Gerhard and David J. Brooks

Current and Future Therapeutic Approaches

Elmyra V. Encarnacion and Thomas N. Chase

Rehabilitation of Patients With Atypical Parkinsonian Disorders

Daniel K. White, Douglas I. Katz, Terry Ellis, Laura Buyan-Dent, and Marie H. Saint-Hilaire

Overview and Future Research

Andrew Lees


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