This volume summarizes how recent exciting advances in immunology have cast new light on autoimmune endocrine disease. These diseases range from relatively common disorders such as diabetes and thyroid diseases to much rarer conditions. All pose immense challenges for the scientist and clinician in their endeavors to link the immunological basis of the problem with its medical consequences. Anthony Weetman clearly introduces the etiology and pathogenesis of autoimmunity and explains new developments in immunology and immunogenetics. He then details the autoimmune disorders that can affect individual endocrine organs. This self-contained, accessible account is a vital resource for clinicians, endocrinologists, and immunologists.