Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 1 - Molecular Mechanisms

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 1 - Molecular Mechanisms

by M. A. Hayat

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Product Details

ISBN-13: 9780124055353
Publisher: Elsevier Science
Publication date: 07/29/2013
Sold by: Barnes & Noble
Format: NOOK Book
Pages: 360
File size: 4 MB

About the Author

Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.

Table of Contents

I. GENERAL DISEASES 1. INTRODUCTION 2. MECHANISMS OF REGULATION OF P62 IN AUTOPHAGY AND IMPLICATIONS FOR HEALTH AND DISEASES  3. MOLECULAR MECHANISMS UNDERLYING THE ROLE OF AUTOPHAGY IN NEURODEGENERATIVE DISEASES 4. ROLES OF MULTIPLE TYPES OF AUTOPHAGY IN NEURODEGENERATIVE DISEASES 5. AUTOPHAGY AND CROHN’S DISEASE: TOWARDS NEW THERAPEUTIC CONNECTIONS 6. THE ROLE OF AUTOPHAGY IN ATHEROSCLEROSIS 7. TREATMENT OF DIABETIC CARDIOMYOPATHY THROUGH UPREGULATING AUTOPHAGY BY STIMULATING AMP-ACTIVATED PROTEIN KINASE 8. HYPERGLYCEMIA-ASSOCIATED STRESS INDUCES AUTOPHAGY: INVOLVEMENT OF THE ROS-ERK/JNK-P53 PATHWAY 9. ROLE OF AUTOPHAGY IN THE CELLULAR DEFENSE AGAINST INFLAMMATION 10. MYTOPHAGY PLAYS A PROTECTIVE ROLE IN FIBROBLASTS FROM PATIENTS WITH COENZYME Q10 DEFICIENCY 11. PRESENCE OF DIOXIN KIDNEY CELLS INDUCES CELL DEATH WITH AUTOPHAGY II. CANCER 12. MOLECULAR MECHANISMS UNDERLYING THE ACTIVATION OF AUTOPHAGY PATHWAYS BY REACTIVE OXYGEN SPECIES AND THEIR RELEVANCE IN CANCER PROGRESSION AND THERAPY 13. INDUCTION OF AUTOPHAGIC CELL DEATH BY ANTICANCER AGENTS 14. IMMUNOGENICITY OF DYING CANCER CELLS - THE INFLAMMASOME CONNECTION. AUTOPHAGIC DEATH ARRIVES TO THE SCENE 15. SELENITE-MEDIATED CELLULAR STRESS, APOPTOSIS AND AUTOPHAGY IN COLON CANCER CELLS 16. ENHANCEMENT OF CELL DEATH IN HIGH GRADE GLIOMA CELLS: ROLE OF N-(4-HYDROXYPHENYL) RETINAMIDE-INDUCED AUTOPHAGY 17. CISPLATIN EXPOSURE OF SQUAMOUS CELL CARCINOMA CELLS LEADS TO THE MODULATION OF AUTOPHAGIC PATHWAY III. TUMORS 18. AUTOPHAGY, STEM CELLS AND TUMOR DORMANCY 19. DEATH- ASSOCIATED  PROTEIN  KINASE 1 SUPPRESSES TUMOR GROWTH AND METASTASIS VIA AUTOPHAGY AND APOPTOSIS 20. TRIM13, NOVEL TUMOR SUPPRESSOR: REGULATOR OF AUTOPHAGY AND CELL DEATH 21.HYPOXIA-INDUCED AUTOPHAGY PROMOTES TUMOR CELL SURVIVAL

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