Basic & Clinical Pharmacology / Edition 10

Basic & Clinical Pharmacology / Edition 10

by Bertram G. Katzung
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Pub. Date:
McGraw-Hill Companies, The

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Basic & Clinical Pharmacology / Edition 10

The current science of pharmacology — and its clinical applications — at your fingertips


"This remains the gold standard of useable texts for teaching pharmacology to medical students. In my opinion, this is the best edition.... continue to use this book as a required resource for all courses that I teach to medical and allied health professions students....I also use this as the major resource for an elective offering in Advanced Pharmacology for third and fourth year medical students. This book continues to be the standard that all other pharmacology books attempt to emulate."—Doody's Review Service

Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula.


•In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs
•Updated with dozens of new, recently approved drugs, including monoclonal antibodies
•Detailed review of the mechanism of action and toxicities of traditional and newer drugs
•Critical discussions of treatment strategies and recommendeddrugs for all major diseases
•Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient
•Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information
•Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements
•More than 500 concept-clarifying illustrations and tables throughout

Product Details

ISBN-13: 9780071451536
Publisher: McGraw-Hill Companies, The
Publication date: 11/24/2006
Series: LANGE Basic Science Series
Edition description: REV
Pages: 1088
Product dimensions: 7.30(w) x 9.10(h) x 1.67(d)

Table of Contents

Schedule of Controlled DrugsInside Front Cover
I.Basic Principles1
2.Drug Receptors & Pharmacodynamics11
3.Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action34
4.Drug Biotransformation51
5.Basic & Clinical Evaluation of New Drugs64
II.Autonomic Drugs75
6.Introduction to Autonomic Pharmacology75
7.Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs94
8.Cholinoceptor-Blocking Drugs109
9.Adrenoceptor-Activating & Other Sympathomimetic Drugs122
10.Adrenoceptor Antagonist Drugs142
III.Cardiovascular-Renal Drugs160
11.Antihypertensive Agents160
12.Vasodilators & the Treatment of Angina Pectoris184
13.Drugs Used in Heart Failure201
14.Agents Used in Cardiac Arrhythmias216
15.Diuretic Agents241
IV.Drugs With Important Actions on Smooth Muscle259
16.Histamine, Serotonin, & the Ergot Alkaloids259
17.Vasoactive Peptides281
18.The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds298
19.Nitric Oxide, Donors, & Inhibitors313
20.Drugs Used in Asthma319
V.Drugs That Act in the Central Nervous System336
21.Introduction to the Pharmacology of CNS Drugs336
22.Sedative-Hypnotic Drugs351
23.The Alcohols367
24.Antiseizure Drugs379
25.General Anesthetics401
26.Local Anesthetics418
27.Skeletal Muscle Relaxants428
28.Pharmacologic Management of Parkinsonism & Other Movement Disorders447
29.Antipsychotic Agents & Lithium462
30.Antidepressant Agents482
31.Opioid Analgesics & Antagonists497
32.Drugs of Abuse517
VI.Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout529
33.Agents Used in Anemias; Hematopoietic Growth Factors529
34.Drugs Used in Disorders of Coagulation543
35.Agents Used in Hyperlipidemia561
36.Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout576
VII.Endocrine Drugs604
37.Hypothalamic & Pituitary Hormones604
38.Thyroid & Antithyroid Drugs625
39.Adrenocorticosteroids & Adrenocortical Antagonists641
40.The Gonadal Hormones & Inhibitors661
41.Pancreatic Hormones & Antidiabetic Drugs693
42.Agents That Affect Bone Mineral Homeostasis716
VIII.Chemotherapeutic Drugs733
43.Beta-Lactam Antibiotics & Other Inhibitors of Cell Wall Synthesis734
44.Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, & Streptogramins754
45.Aminoglycosides & Spectinomycin764
46.Sulfonamides, Trimethoprim, & Quinolones773
47.Antimycobacterial Drugs782
48.Antifungal Agents792
49.Antiviral Agents801
50.Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants828
51.Clinical Use of Antimicrobial Agents836
52.Basic Principles of Antiparasitic Chemotherapy852
53.Antiprotozoal Drugs864
54.Clinical Pharmacology of the Anthelmintic Drugs886
55.Cancer Chemotherapy898
57.Introduction to Toxicology: Occupational & Environmental958
58.Heavy Metal Intoxication & Chelators970
59.Management of the Poisoned Patient982
X.Special Topics995
60.Special Aspects of Perinatal & Pediatric Pharmacology995
61.Special Aspects of Geriatric Pharmacology1007
62.Dermatologic Pharmacology1015
63.Drugs Used in the Treatment of Gastrointestinal Diseases1034
64.Therapeutic & Toxic Potential of Oyer-the-Counter Agents1064
65.Botanicals ("Herbal Medications") & Nutritional Supplements1076
66.Rational Prescribing & Prescription Writing1091
Appendix IVaccines, Immune Globulins, & Other Complex Biologic Products1101
Appendix IIImportant Drug Interactions & Their Mechanisms1110

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