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Human Kinetics, Inc.
Biochemistry Primer for Exercise Science-4th Edition / Edition 4

Biochemistry Primer for Exercise Science-4th Edition / Edition 4


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Product Details

ISBN-13: 9780736096058
Publisher: Human Kinetics, Inc.
Publication date: 05/01/2012
Edition description: New Edition
Pages: 312
Sales rank: 494,959
Product dimensions: 8.40(w) x 10.90(h) x 0.90(d)
Age Range: 18 Years

About the Author

Peter M. Tiidus, PhD, is a professor and former chair of the department of kinesiology and physical education at Wilfrid Laurier University in Waterloo, Ontario, Canada. For more than 30 years, he has focused his research on the physiological mechanisms of and practical interventions in muscle damage and repair, employing both animal models and human subjects.

Tiidus has authored more than 80 publications and presented his research in multiple lectures and conference presentations on estrogen and muscle damage, inflammation, and repair and the influence of treatment interventions on muscle recovery from damage and physiological responses. He currently serves as an editorial board member for Medicine & Science in Sports & Exercise. He is also a former member of the board of directors of the Canadian Society for Exercise Physiology.

A. Russell Tupling, PhD, is an associate professor in the department of kinesiology at the University of Waterloo in Ontario, Canada. His research program, which is funded by the Natural Sciences and Engineering Research Council of Canada and the Canadian Institutes of Health Research, is dedicated to the understanding of the regulation of sarcoplasmic reticulum (SR) function in muscle and understanding how defects in the function of SR proteins that occur with oxidative stress contribute to fatigue, weakness, and disease. In 2009, he received an Early Research Award from the Government of Ontario to conduct research examining a potential link between Ca2+ pump energetics in muscle and metabolic disorders.

Tupling has 49 peer-reviewed publications in scholarly journals and over 70 conference abstracts based on his research. In 2010, he won the Award of Excellence in Graduate Supervision, which was established by the University of Waterloo in recognition of exemplary faculty members who have demonstrated excellence in graduate student supervision. Tupling is a member of the American Physiological Society and the Canadian Society for Exercise Physiology (CSEP). He was invited to give the inaugural Mike Houston Tutorial Lecture in Skeletal Muscle at the CSEP conference in 2009.

Michael E. Houston, PhD, received his undergraduate training in biochemistry from the University of Toronto and his PhD in biochemistry from the University of Waterloo. A superb athlete and lifelong exercise fanatic, he was able to integrate his training in biochemistry with his love of exercise sciences and to forge a career as a teacher and scientist in the field of kinesiology. For almost 40 years during his career, he authored more than 100 refereed publications and taught courses on the biochemistry of exercise to many undergraduate and graduate students. In 2003, he was presented with the Honour Award from the Canadian Society for Exercise Physiology in acknowledgment of his lifetime contribution to research and education in exercise science.

Houston was the author of the first three editions of Biochemistry Primer for Exercise Science. This fourth edition, which is built on his body of work, still incorporates a major portion of his third edition. Dr. Houston passed away in 2008.

Table of Contents

Part I: Proteins and Enzymes: The Basis of Biochemistry

Chapter 1: Amino Acids, Peptides, and Proteins

Nature of Amino Acids

Characteristics of Peptides

Structure of Proteins

Next Stage: Proteomics


Review Questions

Chapter 2: Enzymes

Enzymes as Catalysts

Rates of Enzymatic Reactions

Enzyme Cofactors

Classification of Enzymes

Protein Transporters

Oxidations and Reductions

Regulation of Enzyme Activity

Measurement of Enzyme Activity

Next Stage: Redox Regulation of the SERCA Pump in Vascular Physiology and Disease


Review Questions

Chapter 3: Gene Transcription and Protein Synthesis



Posttranscriptional Modifications of RNA


Posttranslational Processing of Polypeptides

Protein Degradation

Regulation of Gene Expression in Exercise and Training

Next Stage: MicroRNAs and the Adaptive Response to Exercise Training


Review Questions

Part II: Metabolism: Regulation and Adaptation to Exercise and Training

Chapter 4: Energy Systems and Bioenergetics

Energy Requirements of Skeletal Muscle

Energy-Rich Phosphates

Energy Systems


Next Stage: Epigenetic Control of Skeletal Muscle Fiber Type and Metabolic Potential


Review Questions

Chapter 5: Oxidative Phosphorylation

Overview of Metabolism


Citric Acid Cycle

Electron Transport Chain

Coupled Phosphorylation

Regulation of Oxidative Phosphorylation

Quantification of Redox Reactions

Oxidants and Antioxidants

Next Stage: Effects of Aging and Exercise Training on Muscle Mitochondria


Review Questions

Chapter 6: Carbohydrate and Related Metabolism


Cellular Uptake of Glucose

Phosphorylation of Glucose


Glycogen Metabolism

Lactate Metabolism

Oxidation of Cytoplasmic NADH


Pentose Phosphate Pathway

Signaling Pathways

Next Stage: Carbohydrate, Exercise Performance, and Fatigue


Review Questions

Chapter 7: Lipid Metabolism

Types of Lipids

Fat Storage and Metabolism

Oxidation of Fatty Acids

Oxidation of Ketone Bodies

Synthesis of Fatty Acids

Fat as Fuel for Exercise

Metabolism During Exercise: Fat Versus Carbohydrate

Adipose Tissue as an Endocrine Tissue


Next Stage: Exercise, 24-Hour Fat Oxidation, and Weight Loss


Review Questions

Chapter 8: Amino Acid and Protein Metabolism

Overview of Amino Acid Metabolism

Degradation of Amino Acids

Urea Cycle

Fate of Amino Acid Carbon Skeletons

Amino Acid Metabolism During Exercise

Additional Roles for Amino Acids

Next Stage: Effects of Diet and Exercise on Protein Degradation and Synthesis


Review Questions

What People are Saying About This

From the Publisher

"This welcome update of the previous edition includes the most recent peer-reviewed literature that examines exercise science in conjunction with the basic sciences. The authors are well-respected scientists in the field and their expertise, in combination with the updated literature, results in a current and trusted information source for this area.”

--Doody’s Book Review (5-star review)


A supplementary course text for upper-undergraduate and graduate students in exercise physiology, exercise biochemistry, and sport nutrition; a reference for professionals in those fields.

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