Reviewer: Michael Easton, MD (Rush University Medical Center)
Description: The second volume of a three-volume reference, this book covers key neurobiological and genetic elements in addictive disorders.
Purpose: The purpose is to provide a basic understanding of the neurobiological and genetic elements lending susceptibility to use, abuse, and dependence. The book considers the neurobiological mechanisms of drug use and drug addiction as well as the animal models developed to gain this knowledge.
Audience: The audience consists of readers familiar with both clinical and preclinical research in addiction, which includes individuals at all educational and clinical levels as well as those involved in public policy related to addictive disorders. The book can also serve as a valuable aid to instructors and students.
Features: The book's four sections cover preclinical animal models, neuroscience, genetics, and neuropharmacology and imaging as they relate to the addictive process. These sections look at how the focus has shifted toward a biological model to explain the development and course of use, abuse, and dependence through advances in technology, the development of animal models, the search for pharmacological treatments, and the growth in the field of genomics.
Assessment: This volume provides an in-depth, detailed review of the wide range of literature on the key neurobiological and genetic elements involved in the development of addictions. This is an exceptional comprehensive reference.