Pub. Date:
Cambridge University Press
The Biology of Oligodendrocytes

The Biology of Oligodendrocytes

by Patricia Armati, Emily Mathey


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Product Details

ISBN-13: 9780521899659
Publisher: Cambridge University Press
Publication date: 12/31/2010
Pages: 304
Product dimensions: 6.00(w) x 9.00(h) x 0.70(d)

About the Author

Patricia Armati is Associate Professor of Neuroscience and co-director of the Nerve Research Foundation, Brain and Mind Research Institute at the University of Sydney, Australia. She has a long standing interest in the cells of the nervous system and the relationship to disease and is editor of The Biology of Schwann Cells (Cambridge University Press, 2007).

Emily Mathey is a postdoctoral scientist at the Brain and Mind Research Institute at the University of Sydney. She has a keen interest in both immunology and neurobiology with particular emphasis on pathogenic antibody responses in demyelinating disease of the peripheral and central nervous systems.

Table of Contents

Preface ix

Contributors xi

1 CNS oligarchs; the rise of the oligodendrocyte in a neuron-centric culture Emily K. Mathey Ariel Arthur Patricia J. Armati 1

2 Comparative biology of Schwann cells and oligodendrocytes Rudolf Martini Janos Groh Udo Bartsch 19

3 Control of oligodendrocyte development and myelination in the vertebrate CNS Robert H. Miller 49

4 Molecular organization of the oligodendrocyte and myelin Grahame Kidd Bruce D. Trapp 64

5 The genetics of oligodendrocytes Joseph A. Nielsen Pierre Lau Lynn D. Hudson 103

6 Immunobiology of the oligodendrocyte David Kremer Orhan Aktas Hans-Peter Hartung Patrick Küry 115

7 Oligodendrocytes and disease: repair, remyelination and stem cells Neil J. Scolding 137

8 Glial progenitor cells and the dynamics of the oligodendrocyte and its myelin in the aged and injured CNS Jurate Lasiene Philip J. Horner 154

9 Oligodendroglial pathology in multiple sclerosis Tanja Kuhlmann Wolfgang Brück 171

10 Glutamate receptors, transporters and periventricular leukomalacia Tara M. Desilva Paul A. Rosenberg 186

References 202

Index 278

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