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This book focuses on the recent surge in research into the pathogenesis and treatment of bipolar disorder, and critically analyses the evidence supporting many of the conventional opinions about the disease. Chapters by leading basic science and clinical researchers from North America and Europe address issues including the very nature of the disease (psychological disorder or brain disease), the role of genetics, the role of cortisol, and the effects of long-term treatment. Based on lectures presented as part of the second European Foundation for Psychiatry at the Maudsley (EFPM) meeting, this book will stimulate discussion and debate on novel views and will question the dogmas of existing practice.
|Publisher:||Taylor & Francis|
|Product dimensions:||6.12(w) x 9.25(h) x 0.80(d)|
Table of Contents
1. The Positive Aspects of Bipolar illness
2. A 40 year study of First Onset Mania in South London.
3. Brain Changes: do they Exist and do they Change?
4. Is the Amygdala too Expansive in Bipolar Disorder?
5. The Maudsley Bipolar Disorder Project: Insights into Pathophysiology
6. Is Any of this Real? The Word from the Grave
7. Transgenic mouse models for affective disorders
8. Now that we have some genes (in Toronto at least)
9. Is there a genetic basis to the brain abnormalities?
10. How Can Bipolar Disorder be Genetically Related to both Schizophrenia and Unipolar Depression
11. Is the HPA Axis at last Paying Dividends?
12. Neuropathology in BPD and Cortisol dysregulation
13. Cortisol in Chicago (from crime of passion to celebrity headline)
14. The biological factors sustaining HPA overactivation in affective disorder
15. Are Neuropsychological Abnormalities in Bipolar Disorder Cause or Consequence of Mood Disorder?
16. Psychological Treatments: Does the evidence stack up?
17. The brain basis of cognitive function in bipolar disorder
18. Lithium, the forgotten drug
19. What are the advantages and disadvantages of atypical antipsychotics or valproate?
20. Is ECT given in Bipolar Disorder and does TMS offer more?
21. Do drugs work for bipolar disorder?
22. Improving outcome by selecting effective long-term treatment
23. The long-term functional outcome of bipolar disorder.
24. Is what we offer to patients half-acceptable?