Pub. Date:
Springer Netherlands
Bone Metastasis and Molecular Mechanisms: Pathophysiology / Edition 1

Bone Metastasis and Molecular Mechanisms: Pathophysiology / Edition 1

by Gurmit Singh, William Orr


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Product Details

ISBN-13: 9781402019845
Publisher: Springer Netherlands
Publication date: 03/31/2004
Series: Cancer Metastasis - Biology and Treatment , #6
Edition description: 2004
Pages: 308
Product dimensions: 8.27(w) x 11.69(h) x 0.03(d)

Table of Contents

List of Contributors Preface; Gurmit Singh
1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model; Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson
2 Quantitation of Bone Metastasis in Experimental Systems; Julie A. Sharp and Erik W. Thompson
3 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease; Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and Gurmit Singh
4 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases; Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard,
Martin Reed, James A. Thliveris and F. William Orr
5 Metastasis in the Bone Marrow Microenviroment; Paolo Bianco, Mara Riminucci and Pamela Gehron Robey
6 The Role of Tumor-Associated Macrophages in Metastasis-Associated Osteolysis; Nicholas. A. Athanasou
7 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease; Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William Orr and Andrew R. Belch
8 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking; Gabri Van Der Pluijm, and Jeroen Buijs
9 Prostate Cancer: Models for Developing Novel Therapeutic Approaches; Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar
10 Potential Therapeutic Targets for Bone Metastasis; Sadmeet Singh and Gurmit Singh
11 OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis; Paul L Kostnuik
12 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer; Wilhelmina C.M. Duivendoorden and Gurmit Singh
13 The Role of Bisphosphonates in Bone Metastasis; Mary Mackenzie and Pierre Major Index

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