Pub. Date:
Oxford University Press, USA
Presynaptic Inhibition and Neural Control / Edition 1

Presynaptic Inhibition and Neural Control / Edition 1

by Pablo Rudomin
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This is a timely review of the mechanisms underlying the presynaptic control of synaptic transmission and the role they play in sensory and motor behavior. Early chapters offer a detailed account of the anatomy, biophysics, and physiology of synaptic transmission at the peripheral and central synapses, focusing on the presynaptic control of transmitter release. Later chapters explore the organization of neural pathways leading to the presynaptic inhibition of transmitter release in segmental reflex pathways. A final section provides examples of the operation of presynaptic control mechanisms during specific sensory and motor functions in mammals, including humans. Integrating synaptic transmission and CNS functions at the systems level, this volume will be of particular interest to researchers studying both areas.

Product Details

ISBN-13: 2900195105161
Publisher: Oxford University Press, USA
Publication date: 11/13/1997
Edition description: New Edition
Pages: 466
Product dimensions: 6.50(w) x 1.50(h) x 9.50(d)

Table of Contents

I. Basic Mechanisms of Presynaptic Control
1. Anatomical Basis for Presynaptic Inhibition on Primary Sensory Fibers, F.J. Alvarez (Wright State University)
2. Chloride Transport, Osmotic Balance and Presynaptic Inhibition, F.J. Alvarez-Leefmans and Andrés Nani (Instituto Mexicano de Psiquiatría, México), Sergio Márquez (University of Texas Medical Branch)
3. Mechanisms and Physiological Implications of Receptor-Mediated Inhibition of Voltage-Dependent Ca2+ Channels, K. Dunlap (Tufts University School of Medicine)
4. Presynaptic Inhibition and Facilitation of Transmitter Release, S.M. Thompson (University of Zurich, Switzerland), M. Capogna and M. Scanziani (University of California, San Francisco)
5. Primary Afferent Depolarization and Presynaptic Inhibition, L. Vyklicky and H. Urbancová (Academy of Science of Czech Republic)
6. Control of Action Potential Invasion into Terminal Arborizations, H.R. Lüscher (University of Bern, Switzerland)
7. Action Potential Propagation Along Primary Afferents and Presynaptic Inhibition in Clarkes's Column of the Spinal Cord, B. Walmsley and M.J. Nicol (University of Newcastle, Australia)
8. Two Types of Inhibition in the Spinal Cord, D.R. Curtis (John Curtin School of Medical Research, Australia)
9. The Relative Contributions of GABAA and GABAB Receptors to Presynaptic Inhibition of Group Ia EPSPs, S.J. Redman (John Curtain School of Medical Research, Australia)
10. Modulation of Transmitter Release From Ia Afferents by Their Preceding Activity- A 'Post-activation Depression', H. Hultborn (University of Copenhagen, Denmark) and J. Nielsen (Christian-Albrechts-Universitat zu Kiel, Germany)
11. Presynaptic Inhibition of Neuromuscular Transmission in Crayfish, D. Cattaert and F. Clarac (Laboratoire Neurobiologie et Mouvement, Marseille)
12. Regulation of Primary Eighth Nerve Synapses on the Mauthner Cell, D.S. Faber and A. Pereda (Medical College of Pennsylvania and Hahnemann University)
13. Some Unanswered Questions About the Mechanisms and Function of Presynaptic Inhibition, P.D. Wall (UMDS, St. Thomas' Campus, London)
II. Presynaptic Control of Segmental Inputs
14. Presynaptic Inhibition and the Anatomy of Group Ia Afferents, R.E. Burke (National Institutes of Health, Bethesda)
15. Ia Fiber Architecture: Implications for the Functional Role of Presynaptic Inhibition, L.M. Mendell (SUNY, Stony Brook)
16. Dynamic Aspects of Presynaptic Function in the Developing Mammalian Spinal Cord, A. Lev-Tov (The Hebrew University Medical School, Jerusalem)
17. Selectivity of the Presynaptic Control of Synaptic Effectiveness of Group I Afferents in the Mammalian Spinal Cord, P. Rudomin , I. Jiménez. and J. Quevedo (Centro de Investigación y de Estudios Avazados del Institito Politécnico Nacional, México)
18. Presynaptic Inhibition Can Act as a Filter of Input from Tendon Organs during Muscle Contraction, D. Zynicki and L. Jami (Univesité René Descartes, Paris)
19. Neuronal Systems Involved in Modulation Synaptic Transmission from Group II Muscle Afferents, E. Jankowska (Goteborg University, Sweden) and J.S. Riddell (University of Glasgow)
20. Presynaptic Inhibition of Synaptic Transmission from Sensory, Interneuronal and Supraspinal Neurons to Spinal Target Cells in Lamprey, A. El Manira, D. Parker et al. (Karolinska Institute, Sweden)
III. Contribution of Presynaptic Control Mechanisms to Sensory and Motor function
21. Differential Control of Presynaptic Inhibition of Ia Terminals during Voluntary Movement in Humans, E. Pierrot-Deseilligny and S. Meunier (Hôpital de la Salpétière, Paris)
22. PAD and Modulation of Evoked Group II Flexion Reflexes during MLR-Evoked Fictive Locomotion, D. McCrea and M.C. Perrault (University of Manitoba, Canada)
23. Presynaptic Mechanisms during Locomotion, S. Rossignol, I. Beloozerova, J.P. Gossard, and R. Dubuc (Université de Montréal, Canada)
24. Modulation of Excitatory Perineal Reflexes and Sacral Striated Sphincter Motoneuron during Micturition in the Cat, S.J. Shefchyk (University of Manitoba, Canada)
25. A Contribution of Dorsal Root Reflexes to Peripheral Inflammation, W.D. Willis, K.A. Sluka, H. Rees, and K.N. Westlund (University of Texas)
26. Modulation of Nociceptive Information at the Presynaptic Terminals of Primary Afferent Fibers, R.F. Schmidt and H.G. Schaible (Physiologisches Institut der Universitat, Würzberg)

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