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Imperial College Press
Plenty of Room for Biology at the Bottom: An Introduction to Bionanotechnology / Edition 2

Plenty of Room for Biology at the Bottom: An Introduction to Bionanotechnology / Edition 2

by Anna Mitraki


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Plenty of Room for Biology at the Bottom: An Introduction to Bionanotechnology / Edition 2

Written by a leading nanobiologist actively involved at the forefront of the field both as a researcher and an educator, this book takes the reader from the fundamentals of nanobiology to the most advanced applications.

The book is written in such a way as to be accessible to biologists and chemists with no background in nanotechnology. It is reader-friendly and will appeal to a wide audience not only in academia but also in the industry and anyone interested in learning more about nanobiotechnology.

The book includes a glossary and a selected list of companies actively involved in nanobiotechnology and will be an important reference for those interested in the application aspects of the field.

Product Details

ISBN-13: 2901848169301
Publisher: Imperial College Press
Publication date: 09/08/2013
Edition description: NE
Pages: 197
Product dimensions: 6.50(w) x 1.50(h) x 9.50(d)

Table of Contents

Preface     xi
Introduction: Nanobiotechnology and Bionanotechnology     1
Classical Biotechnology: Industrial Production Using Biological Systems     2
Modern Biotechnology: From Industrial Processes to Novel Therapeutics     3
Modern Biotechnology: Immunological, Enzymatic, and Nucleic Acids-Based Technology     5
The Interface Between Nanotechnological and Biotechnology: Bionanotechnology     7
Supramolecular (Bio)Chemistry: The Theoretical Basis for Self-Assembly     9
The Next Steps for Self-Association at the Nano-Scale     10
Biology in Nanotechnology and Nano-Sciences in Biotechnology     11
The Combination of Bionanotechnology and Nanobiotechnology     13
Nanobionics and Bio-Inspired Nanotechnology     14
A Brief Introduction to Nanotechnology     17
The Emergence of Nanotechnology: "There's Plenty of Room at the Bottom"     17
Coining the Term "Nanotechnology" and Emergence of the Nanotechnology Concept     19
Manipulating Molecules: The Scanning Probe Microscopes     20
Carbon Fullerene: A New Form of Carbon     23
Carbon Nanotubes: Key Building Blocks for Future Nanotechnological Applications     26
Non-Carbon Nanotubes and Fullerene-Like Material: The Inorganic Nanomaterials     28
Quantum Dots and Other Nano-Particles     30
Nanowires, Nanorods, and Other Nanomaterials     31
Magnetic Nanoparticles     31
Natural Biological Assembly at the Nano-Scale     33
The Process of Self-Assembly and Self-Organization in Biology     33
Organization of Bacterial S-Layers     35
Self-Organization of Viruses     37
Self-Organization of Phospholipids Membranes     40
Fibrillar Cytoskeleton Assemblies     42
Nucleic Acids: The Genetic Information Media and a Template for Nanotechnological Applications     45
Oligosaccharides and Polysaccharides: Another Class of Biological Polymers     46
Amyloid Fibrils as Self-Assembled Nano-Scale Bio-Assemblies     47
Silk: Natural Fibrillar Supramolecular Protein Assembly     48
Ribosome: The Protein Assembly Line Instrument     49
Other Complex Machines in the Genetic Code Expression     50
Protein Quality-Control Machinery: The Proteosome     50
Biological Nano-Motors: Kinesin and Dynein     51
Other Nano-Motors: Flagella and Cilia     51
Ion Channels: Nano-Pores of High Specificity     52
Nanometric Biological Assemblies: Molecular and Chemical Basis for Interaction     55
Emergence of Biological Activity Through Self-Assembly     55
Molecular Recognition and Chemical Affinity     56
Affinity and Specificity of Biological Interactions     58
The Relation Between Thermodynamics and Kinetics of Dissociation     59
The Chemical Basis for Molecular Recognition and Specific Binding     60
The Formation Specific Complexes by an Increase in Entropy     62
Molecular Recognition and the Formation of Biological Structures     65
Antibodies as the Molecular Sensors of Recognition     65
Selection of Antibodies and Equivalent Systems in the Test Tube     67
Recognition Between Nucleic Acids by Proteins     69
Interaction Between Receptors and Ligands     70
Molecular Recognition Between Nucleic Acids     71
Self-Assembly of Biological and Bio-Inspired Nano-Materials     73
Formation of DNA-Based Materials     73
Peptide-Based Nanomaterials     76
The First Peptide Nanotubes     77
Amphiphile and Surfactant-Like Peptide Building-Blocks     79
Charge Complementary as a Driven Force for Self-Assembly     81
Conjugation of Peptides for Self-Assembly     81
Aromatic Interactions for the Formation of Nanostructures     83
The Formation of Aromatic Dipeptide Nanotubes (ADNT)     84
The Formation of Spherical Nanostructures by Short Peptides     87
Peptide Nucleic Acid (PNA)     87
Application of Biological Assemblies in Nanotechnology     89
The Use of S-Layer for Nanolithography     89
The Use of DNA for Fabrication of Conductive Nanowires     91
Amyloid Fibrils as Templates for Nanowires Fabrication     94
Metallization of Actin Filaments by Chemical Modification     95
The Use of Aromatic Peptide Nanotubes     97
Bacteriophages as Novel Biomaterials     98
The Use of Peptide Template for Biomineralization     98
Production of Inorganic Composite Nanomaterial     99
The Utilization of Biomineralization in Nanotechnology     100
Medical and Other Applications of Bionanotechnology     103
The Use of Drug Nanocrystals for Improved Application     103
The Use of Nano-Containers for Drug Delivery     104
The Use of Inorganic Nanowires for Biological Detection     106
The Use of Soft Lithography for Biotechnology     108
Contrast Agents by Nanomagnetic Materials     109
Nanoagriculture     110
Water Technology and Nanotechnology     111
Nanocosmetics      112
Solar Energy Applications     113
Future Prospects for Nanobiotechnology and Bionanotechnology     115
The Marriage of Molecular Biology and Nanotechnology     115
The Engineering of Modified Biological Systems for the Assembly of Nanostructures     116
Nanotechnology and Tissue Engineering     117
Engineering of the Brain Tissue     119
Making Artificial Biological Inorganic Composites     120
Nanobio Machines and Nanorobots     121
Concluding Remarks: The Prospects and Dangers of the Nanobiological Revolution     123
There's Plenty of Room at the Bottom: An Invitation to Enter a New Field of Physics - by Richard P. Feynman     129
List of Bionanotechnological and Nanobiotechnological Companies     147
Glossary     161
Bibliography     171
Index     181

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