Pub. Date:
Springer Netherlands
Calcium Signalling and Disease: Molecular pathology of calcium / Edition 1

Calcium Signalling and Disease: Molecular pathology of calcium / Edition 1

by Ernesto Carafoli, Marisa Brini


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Product Details

ISBN-13: 9781402061905
Publisher: Springer Netherlands
Publication date: 12/06/2007
Series: Subcellular Biochemistry , #45
Edition description: 2007
Pages: 592
Product dimensions: 6.10(w) x 9.25(h) x 0.05(d)

Table of Contents

Prologue.- Calcium sensor proteins and disease.- Calpains and human disease.- Gelsolin and diseases.- Guanylate cyclase activating proteins and retina disease.- Pathalogies involving the S100 proteins and RAGE.- The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics.- Physiological roles of the Ca2+/CaM-dependant protein kinase cascade in health and disease.- Calcium channelopathies.- TRP channels in disease.- Diseases associated with altered ryanodine receptor activity.- Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington’s disease.- Calcium pumps and disease.- The plasma membrane calcium ATPase and disease.- Diseases involving the Golgi calcium pump.- Calcium signalling and cancer cell growth.- Calcium misregulation and the pathogenesis of muscolar dystrophy.- Calcium and cell death.- Calcium and cell death: the mihondrial connection.- Role of calcium in the pathogenesis of Alzheimer’s disease and transgenic models.- Calcium and cardiomyopathies.- Calcium signalling and calcium transport in bone disease.

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