Calcium Signalling and Disease: Molecular pathology of calcium / Edition 1 available in Hardcover
- Pub. Date:
- Springer Netherlands
Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.
Table of Contents
Prologue.- Calcium sensor proteins and disease.- Calpains and human disease.- Gelsolin and diseases.- Guanylate cyclase activating proteins and retina disease.- Pathalogies involving the S100 proteins and RAGE.- The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics.- Physiological roles of the Ca2+/CaM-dependant protein kinase cascade in health and disease.- Calcium channelopathies.- TRP channels in disease.- Diseases associated with altered ryanodine receptor activity.- Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington’s disease.- Calcium pumps and disease.- The plasma membrane calcium ATPase and disease.- Diseases involving the Golgi calcium pump.- Calcium signalling and cancer cell growth.- Calcium misregulation and the pathogenesis of muscolar dystrophy.- Calcium and cell death.- Calcium and cell death: the mihondrial connection.- Role of calcium in the pathogenesis of Alzheimer’s disease and transgenic models.- Calcium and cardiomyopathies.- Calcium signalling and calcium transport in bone disease.