Cardiac Rate and Rhythm: Physiological, Morphological and Developmental Aspects

Cardiac Rate and Rhythm: Physiological, Morphological and Developmental Aspects

Paperback(Softcover reprint of the original 1st ed. 1982)

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Product Details

ISBN-13: 9789400975378
Publisher: Springer Netherlands
Publication date: 10/12/2011
Series: Developments in Cardiovascular Medicine , #17
Edition description: Softcover reprint of the original 1st ed. 1982
Pages: 696
Product dimensions: 6.10(w) x 9.25(h) x 0.06(d)

Table of Contents

Section One: Fundamentals of Pacemaker Activity.- Pacemaker Mechanisms.- On the Ultrastructural Identification of Pacemaker Cell Types within the Sinus Node.- Pacemaker Mechanisms of Rabbit Sinoatrial Node Cells.- The Relative Contributions of Various Time-dependent Membrane Currents to Pacemaker Activity in the Sino-Atrial Node.- The Current IK2 in Purkinje Fibres Reinterpreted and Identified with the Current If in the SA node.- Implications of the Re-interpretation of IK2 for the Modelling of Electrical Activity of Pacemaker Tissues in the Heart.- Pacemaker Mechanisms in Myocardial Cells during Development of Embryonic Chick Hearts.- Section Two: Interaction of Pacemaker Cells.- Cellular Communication: Introductory Remarks.- On the Control of Cell Communication in Heart.- Electrical Cell Coupling in Rabbit Sino Atrial Node and Atrium: Experimental and Theoretical Evaluation.- Gap Junction Structure under Coupled and Uncoupled Conditions.- Formation and Growth of Myocardial Gap Junctions: In Vivo and In Vitro Studies.- Intercellular Coupling between Embryonic Heart Cell Aggregates.- Intercellular Coupling between Cardiac Cells and its Disturbances.- Ectopic Activity in the Early Phase of Regional Myocardial Ischemia.- Section Three: Establishment of Cardiac Rhythm.- In Vitro Models of Entrainment of Cardiac Cells.- Synchronization of Cardiac Pacemaker Cells by Electrical Coupling: a Study with Embryonic Heart Cell Aggregates and Pacemaker Cell Models.- Factors Influencing Regularity and Synchronization of Beating of Tissue Cultured Heart Cells.- Synchronization of Hodgkin-Huxley Type and Related Oscillators.- Dynamic Properties of Electrically Interacting Excitable Cells.- Fibrillation as a Consequence of Pacemaker Phase-resetting.- Section Four: Neural Control of Rate and Rhythm.- On the Intrinsic Cardiac Rhythm.- Mode of Action of Acetylcholine on the Rabbit SA Node Cell.- Interaction of Adrenaline and Acetylcholine on Sinus Node Function.- Conduction within the Sinus Node and its Modification by Autonomic Drugs.- The Effects of Brief Vagal and Sympathetic Stimulation on Rate and Rhythm Changes in the Sinus Node.- The Phase-dependent Effects of Repetitive Bursts of Vagal Activity on Heart Rate.- Entrainment of the SA Nodal Pacemaker by Brief Vagal Bursts in Relation to AV Conduction.- Properties of the Fast Sodium Channel and of the Muscarinic Receptor during Development of Embryonic Heart Cells In Ovo and In Vitro.- Initiation of Transmitter Secretion by Adrenergic Neurons and its Relation to Morphological and Functional Innervation of the Embryonic Chick Heart.- References.

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