Cell Cycle Deregulation in Cancer

Cell Cycle Deregulation in Cancer

by Greg H. Enders (Editor)


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Product Details

ISBN-13: 9781461425694
Publisher: Springer New York
Publication date: 05/04/2012
Series: Current Cancer Research
Edition description: 2010
Pages: 206
Product dimensions: 6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Starting the cell division cycle

Elena Sotillo and Xavier Graña

Escape from cellular quiescence

Jun-Yuan Ji and Nicholas J. Dyson

Interplay between Cyclin-dependent Kinases and E2F-dependent Transcription.

A. Kathleen McClendon, Jeffry L. Dean, and Erik S. Knudsen
Regulation of pre-RC assembly: A complex symphony orchestrated by CDKs

Proliferation under duress

Haomin Huang and Timothy J Yen

Mitotic checkpoint and chromosome instability in cancer

Jeremy P.H. Chow and Randy Y.C. Poon

Mitotic catastrophe

Robert D. Hontz and Maureen E. Murphy

p53, ARF and the control of autophagy

Long-term proliferation

Andrea Viale and Pier Giuseppe Pelicci

Regulation of self-renewing divisions in normal and leukaemia stem cells

Eros Lazzerini Denchi

Maintenance of Telomeres in Cancer

Peter D. Adams

The senescence secretome and its impact on tumor suppression and cancer

Applications in preventing and treating cancer

Pierre Lao-Sirieix and Rebecca C Fitzgerald

Cell cycle deregulation in pre-neoplasia: case study of Barrett’s esophagus

Neil Johnson and Geoffrey I. Shapiro

Targeting cyclin dependent kinases for cancer therapy

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