Chronic Hepatitis B And C: Basic Science To Clinical Applications

Chronic Hepatitis B And C: Basic Science To Clinical Applications

by Chiaho Shih (Editor)


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The scope of the book is very broad, covering a wide range of areas in HBV/HDV and HCV research, including both basic and clinical science. The selected topics range from epidemiology, immunology, molecular virology and oncology, to clinical therapy.Chronic Hepatitis B and C consists of 14 chapters, each being a review of a special topic on HBV or HCV. While review articles on a special topic can be found in periodical journals, they tend to be more restricted in presentation. Therefore, this book will provide more in-depth coverage of what are presented as “unpublished results” and “data not shown” in journal articles. Furthermore, several authors in this book do not write review articles regularly. Some authors wrote reviews on a specific topic regularly, but they tried a new topic in this book (e.g., Dr. YF Liaw on “natural course,” Dr. Shih on “virion release,” Dr. Michael Lai on “lymphotropism of HCV,” etc. ⋯). Overall, the book will offer useful information at the cutting age.Sample Chapter(s)

Product Details

ISBN-13: 9789814299787
Publisher: World Scientific Publishing Company, Incorporated
Publication date: 11/14/2012
Pages: 416
Product dimensions: 6.00(w) x 9.00(h) x 0.90(d)

Table of Contents

Foreword v

Preface ix

Contributors xiii

Hepatitis B Virus 1

Chapter 1 Natural Course of Chronic Hepatitis B Virus Infection Chia-Ming Chu Yun-Fan Liaw 3

Chapter 2 Immune Response and Viral Hepatitis B David R. Milich 35

Chapter 3 Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma Katherine A. McGlynn Alison A. Evans W. Thomas London 71

Chapter 4 Molecular Biology of HBV-related Hepatocellular Carcinoma Amanda J. Hodgson Betty L. Slagle 99

Chapter 5 Treatment of Chronic Viral Hepatitis B and Drug Resistant Variants Tin Nguyen Paul Desmond Stephen Locarnini 133

Chapter 6 Virion Secretion of Naturally Occurring Core Antigen Variants of Human Hepatitis B Virus Chiaho Shih 167

Chapter 7 Recent Developments in Hepatitis Delta Virus Camille Sureau 197

Hepatitis C Virus 229

Chapter 8 Development of an HCV Cell Culture System Takanobu Kato Takaji Wakita 231

Chapter 9 Regulation of Innate Immunity and Interferon Defenses by Hepatitis C Virus Stacy M. Horner Michael Gale Jr 245

Chapter 10 Expression and Functions of Hepatitis C Virus F Protein Kamile Yuksek Jing-hsiung James Ou 271

Chapter 11 Lymphotropism of Hepatitis C Virus Keigo Machida Michael M.C. Lai 293

Chapter 12 Host Genetic Factors Control Hepatitis C Virus Infection Yasuhito Tanaka Masashi Mizokami 325

Chapter 13 Treatment of Hepatitis C Virus Infection: Past, Present and Future Chun-Jen Liu Ding-Shinn Chen 341

Chapter 14 Individualized Therapy for Chronic Hepatitis C Ming-Lung Yu Wan-Long Chuang 373

Index 395

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